Ask Fabio

Ask Fabio Dr. Fabio Castiglione is a consultant andrologist at King's College Hospital in London

🎬 New Video Alert! 🎬What Is  Hypogonadism?What is Hypogonadism?Male hypogonadism is a term that refers to a condition in...
03/10/2025

🎬 New Video Alert! 🎬

What Is Hypogonadism?

What is Hypogonadism?
Male hypogonadism is a term that refers to a condition in which the testicles produce less testosterone than the body needs to function optimally. To fully understand it, it is essential first to understand the fundamental role of the testicles in the male body. The testicles are the primary male organs and are responsible for the production of testosterone, a key hormone for men's health and well-being. Testosterone plays a multifunctional role, influencing muscle growth, bone density, body fat distribution, s***m production, and even energy and s*xual desire. Male hypogonadism occurs when the testicles do not produce enough testosterone to meet the body's needs. This can result from a variety of causes and is a condition that can have a significant impact on men's physical and mental health.

Types of Hypogonadism
Male hypogonadism can be divided into two main categories: primary and secondary, or hypergonadotropic hypogonadism and hypogonadotropic hypogonadism, respectively. These two types differ in their underlying causes and hormonal dynamics involved.

Primary hypogonadism occurs when dysfunction of the testicles is the main cause of reduced testosterone production. This condition can be due to congenital factors, infections, trauma, or other problems directly related to the testicles themselves. In this form of hypogonadism, the body responds to low testosterone production by increasing the secretion of luteinizing hormone (LH). LH is a hormone produced by the pituitary gland and plays a crucial role in stimulating the testicles to produce testosterone. Despite this increase in LH, the testicles fail to respond appropriately, leading to inadequate testosterone production.

Secondary hypogonadism, on the other hand, is often caused by problems in the hypothalamus or pituitary, two glands in the brain that regulate hormonal production. In this case, the production of LH and follicle-stimulating hormone (FSH) is reduced, preventing adequate stimulation of the testicles. As a result, even if the testicles may be structurally healthy, they produce less testosterone than necessary due to the lack of appropriate hormonal stimulation.

These differences in the underlying mechanisms of primary and secondary hypogonadism affect the treatment and management of the condition. It is essential to identify the type of hypogonadism in a patient to determine the most appropriate and targeted treatment plan.

▶️Watch the video till the end and let me know your thoughts in the comments. If you like this video, please SUBSCRIBE and don’t forget to press the bell 🔔, like, comment and share. Stay safe and Love all. 😍 Fabio Castiglione MD PhD is a urologist and andrologist on youtube to educate people about all things urology including erectile dysfunction, how to increase testosterone, problems with s*x, premature ej*******on, urinary leakage, or incontinence, overactive bladder, urinary tract infections, prostate issues and more.
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▶️DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Fabio Castiglione Md PhD will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.

📺 Watch now: https://www.youtube.com/watch?v=fxCGUhSoRkY

- Dr Fabio Castiglione

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