29/08/2025
https://www.allergycliniclondon.co.uk/allergy-or-parasites. 🔬 IgE Allergies & Parasites
IgE’s Dual Role:
Immunoglobulin E (IgE) is a key antibody involved in both defending against parasitic infections (like helminths) and triggering allergic reactions (e.g., asthma, food allergies).
Key Insights:
· Parasite Interaction: Helminth infections can either suppress or exacerbate allergies via immune modulation or cross-reactive allergens.
· Diagnosis Challenges: In parasite-endemic areas, IgE tests may show false positives due to cross-reactivity.
· Treatment Advances:
· Omalizumab (anti-IgE therapy) helps manage severe allergies.
· Allergen immunotherapy (AIT) induces long-term tolerance.
Takeaway:
Understanding IgE’s role in parasites and allergies improves diagnostics and personalised treatments, especially in regions with high parasite prevalence.
💡 For deeper insights, check out the full article!
