Evolve - Physical and Mental Longevity Clinic

14/08/2025

Mounjaro users, brace yourselves: prices are set to jump by 170% starting 1 Sept—
but NHS access stays unchanged. Is this just ‘fair global pricing’ or pressure applied at our expense? What are your plans if costs surge—stick, switch, seek support? And will the next newcomer, Retatrutide, be any better? Share your thoughts …

Mounjaro (tirzepatide) used for diabetes and weight-loss—from about £92–£122 per month to £133–£330, depending on dose. That’s up to a 170% hike in private pay pricing. The NHS price, however, remains protected under existing agreements.

Why the steep increase?
Eli Lilly initially priced Mounjaro lower in the UK to ensure fast NHS access. Now, they’re aligning it with European markets to ensure “fair global contributions to the cost of innovation.”


This move also follows pressure from the U.S. government. President Donald Trump has issued an executive order / MFN policy pushing pharma companies to lower drug prices in the U.S.—and raise them abroad to rebalance the system with US costs as high as $1600 per pen.

Will this price out those who need it the most? What do you think of the price increase? Comment below and let’s chat

08/08/2025

Here we are again..

The joy and the pain of having adult children is vastly different from one day to the next. I’m proud of all 3 of my boys but this one is the first to test my view of life for my kids.

He’s the first try my patience and sanity but I can’t imagine another amazingly clever, confident and beautiful young man have me worry about him 24/7 (usually because he speeds up to drive around corners - who does that?!).

The stars will always shine for you .evans1 you are a force and we believe in you and the good you will do ######

24/07/2025

🧬 The Rise of Peptides in UK Longevity Medicine

There’s a clear upward trend in peptide use across the UK—with more people exploring these powerful biomolecules for anti‑aging, recovery, metabolism, and overall wellbeing. A 2024 netnographic study analysed nearly 15,000 UK forum posts across 493 unique threads, showing a sharp rise in synthetic peptide use (notably BPC‑157, TB‑500, CJC‑1295) for wellbeing and post‑injury recovery, especially among older men seeking anti‑aging and gym performance enhancements.

➤ What are peptides?
Peptides are short chains of amino acids (2–50 units), much smaller than proteins. They function as biological messengers—hormones, enzymes, neurotransmitters—that influence processes like metabolism, immune response, and tissue repair . Famous examples include insulin, oxytocin, and newer therapies like semaglutide (Ozempic) and tirzepatide (Mounjaro)—all peptide‑based .

➤ Why the growing interest in longev­i­­ty?

Peptides are increasingly used by UK clinics specialising in longevity and regenerative medicine to target cellular ageing pathways and tissue repair.
• Growth hormone peptide analogues (e.g. CJC‑1295, Ipamorelin): may help increase lean muscle, reduce fat, support sleep, and improve metabolic health.
• Tissue‑repair peptides (e.g. BPC‑157, TB‑500): support healing and recovery from injury, especially musculoskeletal.
• Mitochondrial and immune‑health peptides (e.g. MOTS‑c, Thymosin Alpha‑1): boost energy, repair mitochondria, and modulate inflammation.

💡 Health benefits (according to current research)
• Faster recovery & tissue repair: Peptides such as BPC‑157 and TB‑500 support healing of muscles, ligaments, and tendons via regenerative pathways and angiogenesis .
• Improved body composition & metabolism: Growth hormone‑releasing peptides may support fat loss, lean mass retention and better sleep .
• Anti‑aging skin & collagen support: Peptides like GHK‑Cu stimulate collagen production, bolster elasticity, and reduce inflammation for a youthful complexion .
• Cognitive & immune support: Some peptides are being explored for enhancing brain function and immunity—though clinical data is still limited

22/07/2025

📉 **GLP-1 Non-Responder? Let’s Talk About It.**⁠
⁠
Two clients recently just aren’t responding to treatment on two different GLP-1s and so I decided to delve into the evidence……

GLP-1 medications like semaglutide or tirzepatide have transformed the weight loss landscape — but they’re not magic. For some, they may not deliver the expected results.⁠
⁠
💡 So when do we consider someone a “non-responder”?

Clinical guidelines suggest:⁠
📆 12 weeks on a therapeutic dose⁠
⚖️

05/07/2025

🧬 Are You Deficient and Don’t Even Know It?
Vitamin D and B12 deficiencies are silent disruptors of your health — and they’re more common than you think.

🔍 Why It Matters:
Low levels of Vitamin D or B12 can lead to:
• Chronic fatigue
• Mood changes & brain fog
• Weak immunity
• Bone & muscle pain
• Nerve damage & memory issues

❗These deficiencies don’t just affect older adults — they impact every age group, often with subtle signs that go unnoticed.

👩‍⚕️ At Evolve Longevity Clinic, we specialise in identifying and treating deficiencies before they impact your long-term wellness. Whether you’re in your 20s or 70s, regular monitoring of your vitamin levels is essential to optimize energy, focus, and resilience.

🧪 It’s a simple blood test. The results can change your life.

📅 Book your comprehensive micronutrient screening today. Your future self will thank you.

26/06/2025

✨ Big changes are coming to the aesthetic industry in Scotland — and they could set the standard for the rest of the UK.

From who can perform injectables to mandatory clinic registration with HIS, these new proposals are all about raising safety, transparency, and trust in the industry.

💉 Non-medics can continue offering treatments — but under tighter regulation and medical supervision.

🏥 Clinics will need to be HIS-registered.
🧑‍⚕️ Only qualified prescribers can oversee higher-risk treatments.
📅 Draft legislation is due by May 2026.

Scotland is leading the way — but will the rest of the UK follow?

👇 Tap through the carousel for what it means for practitioners, clients & clinic owners.

23/06/2025

📢 Important Update: Kenalog Injections at Evolve Clinic 💉🚫

We’re so grateful to our current and potential clients who reach out with thoughtful questions about treatments, especially regarding Kenalog injections for hay fever relief.

While Kenalog was once a popular option, we want to be fully transparent: Kenalog is no longer recommended under current UK NICE (National Institute for Health and Care Excellence) guidance. In fact, it was withdrawn from routine use in the UK in 2019 due to significant safety concerns.

⚠️ Why the change?
Kenalog contains a steroid (triamcinolone) that, when injected, suppresses the immune system for an extended period. This can lead to serious side effects, including:
• Reduced ability to fight infections
• Mood changes
• Hormonal imbalances
• Adrenal suppression
These risks are especially concerning when used for non-life-threatening issues like seasonal allergies.

✅ So, what are the safer alternatives?
At Evolve Clinic, we care deeply about your long-term health. That’s why we now focus on NICE-recommended treatments, which may include:
• Antihistamines (oral or nasal)
• Nasal corticosteroid sprays
• Allergy management plans tailored to you

🌸 Struggling with hay fever symptoms? Let’s talk! We are are happy to guide you toward evidence-based, safer solutions that work for you.

📩 DM or book a consultation to discuss your options today.

18/06/2025

🧬 Struggling with Low Energy, Mood Swings or Low Libido? It could be low testosterone.

Many men in the UK experience symptoms of hormonal imbalance, but don’t realise it’s a medical issue — not just “getting older.”

👇 Common symptoms of testosterone deficiency:
✅ Fatigue & brain fog
✅ Low s*x drive or erectile issues
✅ Mood changes, anxiety or irritability
✅ Increased body fat, decreased muscle
✅ Poor sleep & motivation

📊 Did you know?
Over 25% of men over 40 in the UK may suffer from low testosterone — yet it’s often underdiagnosed.

⸻

💉 Hormone Replacement Therapy (HRT) can help restore balance and change your life.
With Evolve, you can expect:

🔹 Medical-grade blood testing & analysis
🔹 Personalised HRT plans with UK prescribers
🔹 Ongoing support & optimisation
🔹 Safe, discreet & clinically backed care

⸻

📍 Based in the UK — We’re helping men nationwide take back control of their health, confidence, and vitality.

⚡️ You don’t have to feel “off” anymore.
📲 DM us or visit www.evolvelongevity.co.uk to book your consultation today.

16/06/2025

🌿✨ Booking Your Consultation at EVOLVE ✨🌿
⠀
We are so grateful for the growing interest in joining our EVOLVE community. 💛
⠀
To ensure your consultation request is received and responded to promptly, please use the contact form on our website to book all appointments.
⠀
🗓️ Kindly note: We are unable to manage bookings via DMs or through unavailable clinic dates. Submissions through the site are reviewed regularly to avoid missing anyone.
⠀
Your time and journey are deeply valued, and this helps us give each request the attention it deserves.

If you have tried to book in via DMs or any other method apologies if you have t had any luck and please fill out a contact form where we will aim to respond in 48 hours.

Note clinic will be closed 04-20 July inclusive so no bookings will be available in this time.
⠀
Thank you for your continued support and trust. We can’t wait to guide you on your path to physical and mental longevity. 🌕🌿
⠀
📍 Book via our website now — link in bio.
⠀

15/06/2025

10/06/2025

🧬 Live Longer, Live Stronger: The Longevity Stack You Should Know About 🧪

Want to age gracefully, stay energetic, and maybe even skip a few of those traditional meds (under expert guidance)? Here’s the evidence-backed supplement stack helping people do just that 👇

1. NMN (Nicotinamide Mononucleotide)
✨ The NAD+ booster your cells love.
As we age, NAD+ (vital for cell repair & energy) declines. NMN helps restore it — improving mitochondrial function, potentially slowing aging, and supporting metabolic health.
🔬 Linked to: increased insulin sensitivity, better brain function, and muscle endurance.

2. Prebiotics + Probiotics
🌿 Gut health = whole-body health.
Prebiotics feed the good bacteria; probiotics are their beneficial byproducts. Together, they reduce inflammation, support immunity, and even improve mood and cognitive health.
💪 May reduce the need for: long-term antacids, laxatives, or even some inflammatory meds (always consult your clinician first!).

3. Omega-3s (DHA/EPA)
💓 The heart-brain-longevity trifecta.
These healthy fats lower inflammation, support cardiovascular health, and may slow cognitive decline.
👋 Can sometimes replace statins or blood pressure meds — again, only with medical supervision.

4. Vitamin D + K2
☀️ The dynamic duo for bones, immunity & heart health.
Most UK residents are deficient — affecting everything from mood to fracture risk. K2 ensures calcium goes to bones, not arteries.
📉 Often reduces the need for calcium or bone medications in the long run.

5. Magnesium (Glycinate or Threonate)
🧠 Sleep, stress & cellular repair in one.
Magnesium supports over 300 processes in the body — and most people are unknowingly deficient.
😌 Helps reduce anxiety, migraines, high BP — and even some antidepressant or pain med reliance (always with guidance).

👩‍⚕️ The Bottom Line:
With the right guidance, these supplements can complement or even replace certain meds, improving quality of life with fewer side effects. Always work with a health professional — especially if you’re managing a health condition.

07/06/2025

🚨 FOLLOWING THE NMC BAN ON REMOTE PRESCRIBING IN AESTHETICS – HERE’S WHY IT MATTERS

The Nursing and Midwifery Council (NMC) has officially banned remote prescribing for aesthetic treatments. This pivotal change underscores the necessity of face-to-face consultations before prescribing prescription-only medicines (POMs) like botulinum toxin. At Evolve, we’ve always championed safe, ethical practice and are proud to support clinics requiring in-person prescribers. 💉👩‍⚕️

📊 The Reality of Aesthetic Complications in the UK:
• In 2022, Save Face, a UK register of accredited cosmetic practitioners, received 2,824 complaints related to dermal fillers and botulinum toxin treatments—a significant increase from previous years.
• A UK survey revealed that 79% of respondents experienced an adverse event following botulinum toxin injections, with anxiety being the most commonly reported issue.

These statistics highlight the critical need for thorough patient assessments and robust clinical oversight.

🧠 Why Face-to-Face Consultations Are Crucial:
Remote prescribing can miss vital red flags. In-person consultations enable comprehensive medical history reviews, physical assessments, and real-time discussions to identify contraindications, allergies, and other concerns that might otherwise be overlooked.

🚨 Beyond Botox – The Importance of Clinical Oversight:
Effective management of complications and emergencies requires immediate access to appropriate medications and interventions, including:
• Adrenaline for anaphylaxis
• Hyaluronidase to address vascular occlusion from dermal fillers
• Antibiotics for infection management
• Antivirals for herpes simplex virus flare-ups
• Steroids for certain inflammatory reactions

📍 It’s Not Just About Treatment – It’s About Comprehensive Care:
Face-to-face prescribers ensure patients have immediate access to care, accountability, and expert intervention, enhancing safety and outcomes.

🤝 Evolve Is Here to Support You:
Whether you’re an injector seeking a reliable prescriber or a clinic aiming to strengthen emergency support protocols, Evolve is committed to helping you deliver safe, compliant, and patient-centered care.