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London Hormone Clinic

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London Hormone Clinic

At London Hormone Clinic we specialise in treating a wide range of hormonal conditions. Jan and Amalia have worked together for several years.

At LHC we have expertise in treating a wide range of hormonal conditions. We aim for hormonal optimization to restore women’s health and wellbeing. We firmly believe that women should not suffer in silence and strive to help our patients recover and achieve their full potential. They had in fact been at the same school (though not quite at the same time). Their passion for promoting bio-identical hormone therapy has inspired them to set up LHC, where they can combine their extensive knowledge with experience. LHC allows them to adopt an integrated approach to optimum health, greatly enhanced by their shared ideology and approach to patient care

14/11/2025

The biggest study of its kind in the United States has found a connection between breast cancer cases and air pollution. The findings, from five large studies across America, reinforce the critical connection between the environment and women’s health, highlighting the need for stronger action and public health policy across the world.

In almost 30,000 cases, exposure to nitrogen dioxide was linked to increased risk of breast cancer. Nitrogen dioxide mainly comes from vehicles emissions and the burning of fossil fuels but can also come from indoor sources such as unvented gas stoves and heaters. Fine particulate matter (particles that are too small to be seen by the naked eye) were also linked to increased incidence. This type of pollution comes from vehicle emissions, power plants and burning fuel, as well as from dust, ash and sea spray. Ozone levels were also seen to have an impact on the presence of tumours.

13/11/2025

“Why did my GP insist on changing my HRT? I feel good and have been on it for years.” It’s a question we’re being asked on an almost daily basis and unfortunately, we don’t have the answers.

What we do know is that GPs are over-stretched, there’s more demand for hormone replacement therapy than ever before and a distinct lack of training and support for front-line health workers when it comes to hormones. We also know that it can’t be for financial reasons, as HRT prescriptions are relatively low cost.

There’s another issue and it’s something we hear time and time again from patients – that they’re just not being listened to and that their symptoms are being ignored or misunderstood.

We know from our years of experience that listening and understanding should come before anything else, and that there can’t be a one-size-fits-all approach to HRT.

To find out more about HRT, our team and the way we work, head to www.londonhormoneclinic.com and contact us with any questions.

12/11/2025

At London Hormone Clinic, we make it a priority to understand each of our patient’s individual requirements, and tailor their treatment plans accordingly. There is no one-size-fits-all approach here – just evidence-based medicine, combined with a personalised, patient-focused approach, delivered with thought and compassion.

We strongly believe that no one should suffer the effects of hormone imbalance, when life changing symptoms are often easy to treat and we do all we can to empower patients with knowledge and understanding so they can take back control of their own health and wellbeing.

If you’d like to know more about our outstanding team of highly experienced hormone specialists, and the way we work, take a look at our website: www.londonhormoneclinic.com

11/11/2025

We’re often asked how GLP-1 medications like Ozempic, Wegovy and Mounjaro work and whether they’re safe. Here is a simple guide…

When we eat food, appetite receptors in the brain are triggered. These release hormones that make us feel full – one of which is GLP-1.

These medications mimic that hormone, making patients feel full when they eat very little, or nothing at all. They also slow the stomach emptying which decreases appetite, allowing people to make better food choices, lose weight and reverse insulin resistance.

As for whether they’re safe. Yes. They can be incredibly helpful for people with diabetes, heart disease and underlying insulin resistance. And those who are at high risk of developing those conditions. But they are being widely misused – taken for weight loss alone and without medical supervision. This is resulting in almost all of people (85% say recent studies) regaining the weight lost when they come off the drugs, and many suffering side effects, which can be serious.

At London Hormone Clinic, we medically prescribe these drugs, carefully and continually monitor patients when they’re on them and support them nutritionally and psychologically. Our approach is different, and it works.

To find out more about weight loss medications, how we use them and why, please contact us. You may also find the articles in the journal section of our website useful: www.londonhormoneclinic.com/journal

10/11/2025

Actress Jennifer Lawrence wants all mothers to know about Zuranolone - a new treatment for post-natal depression that’s approved for use in the US and Europe but is still under review by the NHS.

It has long been known that the hormonal cause of post-natal depression is low progesterone. Giving new mothers high-dose progesterone soon after giving birth can help prevent and reverse even the most severe post-natal depression.

But, as with many hormonal issues, the medical profession and ‘Big Pharma’ are not motivated by these inexpensive and safe treatments. They prefer to make novel synthetic medications which make a profit and release money that can fund large scale studies.

This new drug Zuranolone is such a medication. It’s a synthetic version of a metabolite of progesterone Allopregnanolone, and its aim is to mimic some of what progesterone does.

Why not then use the actual hormone, rather than a derivative?

That said - it seems so far to be effective in the women that have used it.

If it can be of any help to women with PND which can be distressing and dangerous and proves to be safe, then it is certainly an improvement in the current regimes available to women.

To find out more about post-natal depression, and how we treat it, head to the website: www.londonhormoneclinic.com or contact us with any questions.

And you can read the full article here: https://www.thetimes.com/article/bef89a69-e8de-451a-9313-87502bddcc7c?shareToken=cb7f151a7477e2ffd5b3e2851e82f53d

04/11/2025

Perimenopause is very confusing and is often misunderstood by women and many in the medical profession.

It usually happens around the age of 48 and it’s when there are fluctuating levels of oestrogen in the body and low levels of progesterone.

At this stage, periods change, they can be irregular, and become very heavy, often coming on without much warning. Women also experience night sweats, insomnia and increased anxiety. This is all completely normal. It’s hormonal.

It’s useful at this stage to have a blood test, but if you can’t get one (most GPs won’t offer one) and you’re having periods, then you are making enough oestrogen and don’t need any more. What you do need is progesterone. And only progesterone.

Very often GPs prescribe both oestrogen and progesterone together, but by adding in more oestrogen when a woman doesn’t need it, symptoms can be made worse. Women can have even heavier bleeding and experience cravings and weight gain. In some cases, they can even end up having a hysterectomy when they don’t need it, all because they were put on oestrogen too early.

To find out more about perimenopause, what it is and when it
happens: www.londonhormoneclinic.com/journal

27/10/2025

Tens of thousands of pens waiting to be filled with unlicensed, unregulated and untested weight-loss drugs have been seized in Northampton.

It’s the largest haul of trafficked weight loss drugs recorded by any law enforcement agency in the world and a stark warning to those buying medicines online and not from registered pharmacies.

The products found are, the UK’s medicines regulatory agency says, "potentially deadly".

This is further evidence that, as we have said many times before, these medications are being hugely misused – simply for weight loss and without medical supervision. As a result, many are experiencing significant side effects and there are lots of cases of, particularly young women, ending up in A&E with serious complications from misusing them.

Mounjaro, Ozempic and Wegovy, when bought from registered pharmacies, prescribed by doctors and used in the way we use them at LHC are safe and there is never a need for side effects.

If you’d like to know more about how we work with weight-loss medications, contact us. This article we write may also be of interest: www.londonhormoneclinic.com/journal/weight-loss-drugs-like-ozempic-arent-for-everyone
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24/10/2025

Dr Jan Toledano spoke to The Guardian's Rose Stokes about the worrying trend for new mothers to start taking GLP-1 medications in a bid to ‘snap-back’ to their pre-pregnancy weight, some even doing so whilst breastfeeding.

“There is”, says Jan, “very little human data on whether GLP-1 medications are absorbed into breast milk and passed onto the baby, but there are animal studies which show that there could be a possible effect on the growth of the baby. Other areas of concern would include the development of normal appetite regulation and gut hormone pathways.”

Jan also points out that there are other potential health risks of taking weight-loss drugs in the postnatal period. “Rapid weight loss could impact milk production, energy levels may decrease which could predispose postnatal depression, and periods could stop which would mask the return to fertility, meaning that women would need to be really careful about contraception if their intention is not to fall pregnant again.”

The women quoted in the article talk of the ease of accessing these medications online without medical intervention and supervision and believe new mothers are being targeted by private companies.
You can read the full article here:
www.londonhormoneclinic.com/in-the-press
And if you’d like to know more about weight-loss medications, please contact us.

22/10/2025

There’s no official widescale research yet, but there is growing anecdotal evidence that taking GLP-1 medications may affect libido – not only reducing appetite for food, but also for intimacy. It’s been seen to be the case for both men and women.

Many in the media have been quick to give their opinions on the reasons why, and of course, it’s complex, but the main cause of reduced libido when on weight loss medications is this…

As weight declines, and insulin resistance improves, the liver produces more s*x hormone binding protein (SHBG). This is a protein that carries testosterone around the body. The more of this protein in the body, the more testosterone is bound to it, which leaves less unbound testosterone to do its job. The effect is relative low testosterone levels, causing low libido and reduced s*xual function, along with muscle loss and possibly other symptoms too.

At London Hormone Clinic, we monitor testosterone in the body and ‘top them up’ if levels become too low. It’s part of our full programme of health checks that we insist any patient on weight loss medications undertakes. And why we have such a high success rate.

If you’d like to know more about GLP-1 medications and the way we work with them, please contact us. You'll also find an interesting article on why weight loss drugs aren't for everyone here: https://www.londonhormoneclinic.com/journal/weight-loss-drugs-like-ozempic-arent-for-everyone

07/10/2025

Menopause care is ‘neglected and inequitable’ in the UK say researchers in the British Medical Journal after finding that hormone replacement therapy prescriptions vary across ethnic and socio-economic groups.

There are many reasons for this…

Despite huge advances in the way women’s health is viewed, women are still reluctant to admit, accept, and seek treatment for symptoms that stem from hormonal changes. The pressure to keep calm and carry on is all around.

Add to this ongoing misogyny in medicine, a lack of understanding about hormone replacement therapy amongst front-line health workers, and a cacophony of misinformation about what happens to our bodies as we age. It is clear to see why so many women are still suffering in silence.

HRT does not increase the risk of any disease, having depleted hormone levels after menopause does. HRT can guard against Alzheimer’s, osteoporosis, cardiovascular disease, macular degeneration, and so much more. And yet, so many women and many in the medical world are still unsure how to use it.

This needs to change and to change fast. More research is needed and an approach that promotes holistic, culturally sensitive and timely care.

And, of course, it’s about education and making sure that those who might benefit from hormone replacement therapy know when and where to access it and feel confident they will be listened to, their symptoms understood and ultimately, that they will receive the right course of treatment.

02/10/2025

You’re going to be hearing lots about menopause and lifestyle in the media over the coming weeks as the theme of World Menopause Month is lifestyle. Specifically, how food, exercise, sleep, stress-management and self-care can impact a woman’s menopause journey.

At London Hormone Clinic, we take a holistic approach to patient care and always consider lifestyle choices as part of the treatment we give. We partner with trusted nutritionists, health coaches and functional medicine specialists, who work with patients to better their health now and in the future.

This is a critical part of our approach, but there is much more to it than that. We know that the starting point in any course of treatment is to firstly replace the hormones that have been lost. This relieves common symptoms such as sleep deprivation, joint aches, anxiety and hair loss and helps to prevent chronic disease in later life, things like osteoporosis, Alzheimer’s, and heart disease.

We use body/bio-identical hormones - these are hormones with exactly the same chemical structure as the hormones the body makes, meaning they do exactly what they are supposed to do, without risks or side effects. And we always start with medications available at high street pharmacies.

We then go a step further, and because we treat the patient and not just the symptoms, we look at other hormones, the thyroid and possible insulin resistance and prediabetes.

So, whilst we understand the importance of a healthy and balanced lifestyle, we also know that it is just one part of the picture.
To find out more about the way we work and what makes us different, check out our website. Link in bio.

23/09/2025

You hear a lot of advice from us, so we thought you might want to see the faces behind the knowledge and find out about our years of expertise.

On the right, is Dr Jan Toledano, clinic founder and owner. An acclaimed expert and pioneer in the field of women's hormonal health. She read medicine at Oxford and UCL, graduating with a distinction in surgery. After training under some of the most renowned doctors in hormonal medicine, she established London Hormone Clinic in 2016. Jan is passionate about combining evidence-based medicine with a unique approach to patient care and is committed to personalised treatment plans.

Next to Jan, is Dr Eleanor King, a qualified GP with a first-class degree in clinical sciences. She’s also a specialist in dermatology. Eleanor is passionate about hormonal health and, like Jan, has trained with internationally renowned doctors in this field. Joining the clinic in 2018, she combines extensive medical and hormonal knowledge with her astute and supportive nature, successfully treating both men and women.

Dr Georgina Leslie studied medicine in Sheffield and obstetrics and gynaecology in London. With extensive experience in ultrasound and fertility issues, she’s also an expert in post-reproductive health. This background combined with her compassionate, insightful approach sees her supporting women of all ages at every stage of their hormonal life cycle.

Dr Shabana Issa graduated from UCL before spending almost twenty years working in London’s hospitals. As a Consultant in Emergency Medicine, she became increasingly aware that chronic conditions could be prevented with the right guidance and support. This sparked her interest in preventative healthcare and hormone medicine, an area in which she has considerable expertise. She combines this extensive knowledge with holistic insights to help patients achieve long-term health and vitality.

You can find out more about our doctors and the way they work here: https://www.londonhormoneclinic.com/who-we-are

Thanks to Brand Photography by Kathryn for the image.

Address

1-2 Jacobs Well Mews
London
W1U3DT

Opening Hours

Monday	9:30am - 5pm
Tuesday	9:30am - 5pm
Wednesday	9:30am - 5pm
Thursday	9:30am - 5pm
Friday	9:30am - 4pm

Telephone

+442039057580

Website

http://www.londonhormoneclinic.com/

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