Insight Health Data Research Hub

19/12/2025

Share your experiences and views on AI in healthcare with the Medicines & Healthcare products Regulatory Agency and help to shape the standards for new AI technologies in the NHS and wider health sector. The agency has launched a call for evidence, open to everyone. Closes 2nd Feb 2026.

05/12/2025

Retinal Vein Occlusion (RVO) - a blockage to a vein in the retina - is a common cause of sudden vision loss and can lead to permanent vision impairment or blindness if left untreated.

For trusted researchers investigating detection and treatment of RVO, INSIGHT at Moorfields Eye Hospital provides access to an anonymised, longitudinal RVO dataset of high-resolution eye images with linked clinical data.

INSIGHT’s recently updated RVO catalogue captures an overview of the data pipeline, including numbers of patients and injections, as well as demographic information.

🔗 View here:https://7877f2f2-4f13-4a87-95fc-ff05dd6a7b8a.filesusr.com/ugd/94ac60_abcc9d67bbc14aa795699b5975ea88f3.pdf

We encourage data access applications from researchers in the NHS, academia, industry, policy, charities, tech and beyond, who are working for patient benefit. INSIGHT also provides clinical expertise through research consultancy for the development of medical AI, supported by the leadership of INSIGHT director Pearse Keane, who is Professor of Artificial Medical Intelligence at UCL Institute of Ophthalmology and a consultant ophthalmologist at Moorfields.

03/12/2025

Diabetic Retinopathy (DR) affects a third of the 4.4 million people estimated to have diabetes in the UK, and is a leading cause of preventable blindness in the adult working population globally.

Through INSIGHT at Moorfields Eye Hospital, DR data is routinely collected from patient appointments, anonymised and curated into information-rich datasets. This data is accessible to researchers working for patient benefit, and is a valuable bio-resource representing the diversity of the population served by Moorfields.

For more information view the recently updated INSIGHT DR data catalogue 🔗https://7877f2f2-4f13-4a87-95fc-ff05dd6a7b8a.filesusr.com/ugd/94ac60_b75339a9e3d04f739a03e813a0484ffb.pdf

Find out how to apply for access
🔗 https://www.insight.hdrhub.org/researcher-overview

01/12/2025

Cataract surgery has grown to become the most frequently undertaken NHS surgical procedure, according to the National Ophthalmology Database Audit.

INSIGHT's curated, anonymised data pipeline of Cataract patients attending routine appointments at Moorfields Eye Hospital provides a rich resource for researchers who are investigating earlier detection and future care pathways for this common condition - affecting 1 in 3 people over the age of 65.

For more information, visit INSIGHT’s recently updated Cataract data catalogue, providing an overview of patient numbers, operations and demographics.
�https://7877f2f2-4f13-4a87-95fc-ff05dd6a7b8a.filesusr.com/ugd/94ac60_6bccb39e79ce46db90de3cf4ed8df006.pdf

INSIGHT's Cataract dataset is one of many across a range of common eye conditions, curated from the world's largest ophthalmic bio-resource, containing more than 30 million eye images linked to clinical data.

Find out more about data at INSIGHT and how to apply for access:
🔗 http://bit.ly/eye-data

27/11/2025

‘Wet’ Age-related Macular Degeneration is the leading cause of irreversible vision loss in older people, and accounts for around 1 in 10 ophthalmology appointments in the NHS.

Increasing patient referrals coupled with workforce shortages have led to concerns over avoidable sight loss due to appointment delays, but large-scale AMD datasets at INSIGHT are underpinning research to improve detection and management, and identify targets for drug discovery.

INSIGHT’s recently updated catalogue for wet AMD data provides a breakdown of anonymised data, collected from routine appointments at Moorfields Eye Hospital, including types of injections and demographic details.

We encourage data access applications from researchers in the NHS, academia, industry, policy, charities, tech and beyond, who are working for patient benefit. INSIGHT also provides clinical expertise through research consultancy for the development of medical AI, supported by the leadership of INSIGHT director Pearse Keane, who is Professor of Artificial Medical Intelligence at UCL Institute of Ophthalmology and a consultant ophthalmologist at Moorfields.

View the AMD data catalogue and find out about access: https://lnkd.in/eSwtG5v5

25/11/2025

Scientific understanding of the link between the eye and the rest of the body is expanding rapidly through the field of .

Pioneered by Moorfields Eye Hospital and UCL Institute of Ophthalmology with INSIGHT, Oculomics uses ocular biomarkers to detect systemic conditions, typically through analysis of large-scale datasets containing both eye and systemic disease information.

Now available through INSIGHT at Moorfields, the Eye Dementia Dataset provides a valuable Oculomics resource for researchers investigating how eye biomarkers could be used for earlier detection of dementia onset and monitoring of disease progression.

The dataset contains secondary care data for some 230,000 patients with dementia diagnosis, attending routine appointments at Moorfields Eye Hospital.

INSIGHT encourages data access applications from researchers in the NHS, academia, industry, policy, charities, biotech and beyond, who are working to advance eye health research for the benefit of patients and wider society.

INSIGHT also provides clinical expertise through research consultancy for the development of medical AI, supported by the leadership of INSIGHT director Pearse Keane, who is Professor of Artificial Medical Intelligence at UCL and a consultant ophthalmologist at Moorfields.

Find out more about the Eye Dementia Dataset, and how to apply for access: https://insight.hdrhub.org/insight-dataset-summaries

24/11/2025

Scientific understanding of the link between the eye and the rest of the body is expanding rapidly through the field of .

Pioneered by Moorfields Eye Hospital and UCL Institute of Ophthalmology with INSIGHT, Oculomics uses ocular biomarkers to detect systemic conditions, typically through analysis of large-scale datasets containing both eye and systemic disease information.

Now available through INSIGHT at Moorfields, the Eye Dementia Dataset provides a valuable Oculomics resource for researchers investigating how eye biomarkers could be used for earlier detection of dementia onset and monitoring of disease progression.

The dataset contains secondary care data for some 230,000 patients with dementia diagnosis, attending routine appointments at Moorfields Eye Hospital.

INSIGHT encourages data access applications from researchers in the NHS, academia, industry, policy, charities, biotech and beyond, who are working to advance eye health research for the benefit of patients and wider society. INSIGHT also provides clinical expertise through research consultancy for the development of medical AI, supported by the leadership of INSIGHT director Pearse Keane, who is Professor of Artificial Medical Intelligence at UCL and a consultant ophthalmologist at Moorfields.

Find out more about the Moorfields Eye Dementia Dataset, and how to apply for access: 🔗 https://lnkd.in/eKtaYqJS

20/11/2025

Consider supporting the world-leading eye research funded by Moorfields Eye Charity at Moorfields Eye Hospital and UCL Institute of Ophthalmology, and buy a Christmas raffle ticket this year.

06/11/2025

INSIGHT has been awarded £3.7 million in funding by UKRI Medical Research Council and the NIHR Moorfields Biomedical Research Centre to expand from Moorfields Eye Hospital and link national health data resources, consolidating the UK as the global leader in ophthalmology and research and innovation.

Led by Pearse Keane and delivered with Moorfields’ strategic partner UCL Institute of Ophthalmology, the four-year project will include:

- on-boarding other NHS sites, including Sunderland Eye Infirmary at South Tyneside and Sunderland NHS Foundation Trust, and creating a comprehensive, interoperable research resource for ophthalmic data

- broadening national data linkages to integrate genetic data from the NIHR BioResource and UK Biobank and accelerate research — using biomarkers in the eye to detect systemic conditions such as dementia and cardiovascular disease

- a major programme of public and patient involvement and engagement

🔗 Find out more:

The UK will benefit from a new initiative to scale the INSIGHT Health Data Research Hub for Eye Health and Oculomics – the world’s largest collection of curated eye imaging and linked clinical data at Moorfields Eye Hospital NHS Foundation Trust.

03/11/2025

Writing for Forbes, reporter Cathy Rubin covers 'code-to-clinic' progress in AI for eye care, with the goal of preventing avoidable sight loss.

Cathy interviews leaders in the field, including Pearse Keane, whose inter-disciplinary research group at UCL Institute of Ophthalmology and Moorfields Eye Hospital is leading the way in developing fair, robust medical AI for detection of eye disease and systemic conditions.

The article covers Pearse's work leading INSIGHT to become the world's largest ophthalmic bioresource for health data research and AI training, and the deployment of RETFound, the world's first AI foundation model for eye health. .

More than 2.2 billion people live with near- or distance-vision impairment, and about 1 billion of those cases were preventable

30/10/2025

Every year, an estimated 40,000 new cases of wet Age-related Macular Degeneration are diagnosed in the UK. To tackle the challenge of rising patient numbers and staffing shortages, a new study has validated an AI system to identify patients who are being under-treated or over-treated for AMD.

This means patients most in need of care could be prioritised for treatment and seen more quickly.

The research, led by Jeff Hogg and Pearse Keane, compared AI-enabled assessments of wet AMD disease activity against real-world clinical assessments at two major NHS eye centres, Moorfields Eye Hospital and Newcastle Eye Centre.

Work by colleagues at UCL Institute of Ophthalmology Moorfields Eye Hospital NIHR Moorfields Biomedical Research Centre

Using artificial intelligence (AI) in eye clinics could reduce both undertreatment and overtreatment of neovascular or ‘wet’ age-related macular degeneration (AMD)

21/10/2025

Professor Pearse Keane has been elected to the US National Academy of Medicine in recognition of his pioneering role developing medical artificial intelligence in ophthalmology, and forging the novel field of - using biomarkers in the eye to detect systemic disease.

Pearse is one of ten international members and 90 US members elected for 2025, announced at the Academy's annual meeting in Washington DC.

Pearse is Professor of Artificial Medical Intelligence at UCL Institute of Ophthalmology, consultant ophthalmologist at Moorfields Eye Hospital and director of the INSIGHT Eye Hub. His work is supported by NIHR Moorfields Biomedical Research Centre and Moorfields Eye Charity.

Read more ⬇️

Professor Pearse Keane has been elected to the US National Academy of Medicine (NAM) in recognition of his pioneering role developing medical artificial intelligence (AI) in ophthalmology and forging the novel field of Oculomics - using biomarkers in the eye to detect systemic disease.