Eye Journal

09/04/2026

Idiopathic intracranial hypertension is increasing, but care across the UK remains inconsistent.

A review of 8 audits covering 469 patients shows gaps in key areas. Diagnostic standards such as lumbar puncture and venography are not consistently met. Visual field testing is often incomplete at presentation. Basic measures like recording weight are frequently missed, despite obesity being the main risk factor. Referral to weight management services remains limited.

Services with structured pathways and dedicated clinics perform better, showing that standardisation works.

There is a clear need for national quality standards. The proposed RISE-IIH framework aims to reduce variation, improve coordination, and deliver more consistent, patient-centred care.



https://www.nature.com/articles/s41433-026-04358-8

07/04/2026

New research highlights a critical reality in neovascular age-related macular degeneration (nAMD) care: outcomes are not equal.

In this Editorial, we explore findings from the National Ophthalmology Database (NOD) AMD Audit, showing that patients from more deprived communities present with worse vision and experience poorer outcomes, despite receiving similar care once in the NHS pathway.

The message is clear. Inequality begins before treatment starts.

Delays in detection, access to primary eye care, and challenges with long-term engagement all play a role. As therapies evolve, improving early diagnosis and ensuring equitable access must be a priority.

Read the full editorial to understand what needs to change and how we can work together to address these disparities.

https://www.nature.com/articles/s41433-026-04423-2

27/03/2026

The first UK consensus paper on managing Dry Eye Disease relevant to the NHS, detailing the patient pathway from primary to tertiary care involving optometrists, nurse practitioners, general and specialist ophthalmologists, is published in Eye.

“Assessment and management of dry eye disease in the UK: standardising reality-based best practice”

Read here: https://www.nature.com/articles/s41433-026-04375-7

23/03/2026

[EYE OPEN]
New research on persistent epithelial defects (PED) shows that amniotic membrane transplant remains an effective treatment option. In a study of 29 patients, healing was achieved in 75.9% of cases.

The study compared cryopreserved membranes (CAM) with vacuum dried membranes (Omnigen) and found no meaningful difference in outcomes. Both approaches led to a significant reduction in stromal bed thickness, with similar results across corneal and epithelial measurements.

These findings suggest that CAM and Omnigen are equally effective in managing PED. ASOCT also proved valuable for tracking healing with objective, quantitative data.

https://www.nature.com/articles/s44440-025-00007-3

04/03/2026

[EYE OPEN] New review highlights key updates to the English Diabetic Eye Screening Programme:

• 2-year screening for some low-risk patients
• R2 retinopathy split into low/high risk
• OCT used to refine maculopathy referrals

As diabetes prevalence continues to rise, innovations like these will be key to sustaining effective national screening programmes and protecting patient sight.

Read here: https://www.nature.com/articles/s44440-026-00014-y

04/03/2026

Eye Reader’s Choice 2024–2025

Discover the most read and cited articles from Eye over the past two years. This collection brings together influential research, insightful reviews and expert commentary from across .

Explore what readers around the world have been reading and citing.

In this Collection we have collated the top read and cited articles from Eye from the past two years. This focus includes a spectrum of articles covering a ...

23/02/2026

[Eye Open] New research explores whether patients with macular disease are comfortable with artificial intelligence being used to guide treatment decisions.

In a survey of 181 participants, respondents were asked to rank different scenarios involving AI or human decision making, varying error rates, turnaround times and whether results were double checked. The findings show that patients are broadly accepting of AI in the assessment of retinal images. What mattered most was accuracy and having a checking mechanism in place, rather than whether the initial decision was made by a human or an AI system.

The study highlights that as AI becomes more integrated into macular clinics, patient priorities should remain central. Clear standards around accuracy and robust oversight will be key to building confidence and supporting safe adoption.

Read in full here: https://www.nature.com/articles/s44440-025-00011-7

11/02/2026

New study of 105 eyes shows a 23G trocar sleeve adapter can dramatically speed up silicone oil injection during vitreoretinal surgery.
Injection time fell from 259s to 90s for Densiron 68, and from 774s to 153s for Silicone 5000, both p < 0.0001. That is a threefold to fivefold reduction.
Only three disconnections occurred. No major complications.
A simple device change may substantially cut operative time. Randomised studies are now needed to confirm these findings.

https://www.nature.com/articles/s41433-026-04279-6

05/02/2026

Changes in hyperreflective choroidal foci over time may predict treatment response and risk of pachychoroid macular atrophy in chronic central serous chorioretinopathy, supporting their role as prognostic biomarkers.
Read now : https://www.nature.com/articles/s41433-026-04277-8

29/01/2026

Vigilance matters: in a 9-year UK study of 664 phthisical eyes, unsuspected intraocular malignancy occurred in 0.75% of cases, all after evisceration. Even with low risk, careful assessment and histopathology are essential.

https://www.nature.com/articles/s41433-025-04224-z

26/01/2026

New research published in Eye Open describes a rare but important complication following DSAEK.

This case report shows how severe corneal melt can appear clinically as a descemetocele even when Descemet’s membrane has already been removed. The authors identify a “pre-descemetocele”, supported by the pre-Descemet’s layer, with evidence of stromal remodelling following treatment.

The findings deepen our understanding of corneal anatomy and have practical implications for diagnosing and managing corneal melt after endothelial keratoplasty.

Read the full article in Eye Open: https://www.nature.com/articles/s44440-025-00008-2

20/01/2026

** NEW IN EYE OPEN **
Diabetic macular oedema lacks a single, standard way to classify disease. That makes diagnosis, treatment decisions, and trial design harder.

This review proposes the C-METRICAL system. It combines clinical assessment, OCT, and angiography, and includes morphology, biomarkers, retinopathy severity, and key systemic comorbidities.

A unified approach could improve consistency in trials and everyday practice, however, further studies are needed to test its real world value.

https://www.nature.com/articles/s44440-025-00009-1