HAIR LABS

HAIR LABS Hair Labs is a computational research lab studying the biology of hair ageing.

Our work turns scientific discovery into real-world protocols — starting with Anti Grey 1.0.

25/03/2026

Each time a new growth cycle begins, the follicle reaches a decision point. Will the new strand grow with pigment, or without it?

Inside the follicle, there are two key zones. At the bottom is the bulb, where the new hair strand forms and pigment is produced. Higher up is the niche, where melanocyte stem cells are stored and prepared for the next cycle.

As long as the signalling between these zones works properly, hair grows with colour. When that process is disrupted, a new strand may grow without pigment.

That is why grey hair is not simply about age. It is also about cellular timing, signalling, and how the follicle functions as a system.

Follow for more explanations of the biology behind greying.

Most hair care speaks to the result. We were more interested in the moment before it.Inside the follicle, a new strand b...
24/03/2026

Most hair care speaks to the result. We were more interested in the moment before it.

Inside the follicle, a new strand begins with a decision point. At the start of a new growth cycle, pigment cells need to activate and move into place. When that process works as it should, the strand grows with colour. When it does not, the strand grows grey.

This is why Anti Grey 1.0 was never designed as a cosmetic fix. It was built around the early biology of pigmentation inside the follicle, where colour is either carried forward or lost before the hair even appears.

19/03/2026

What if we could hit “pause” on the biological clock of your hair?
To study greying properly, researchers needed a model that would not take forever. So the team at Nagoya University used RET-mice — a fast-track model of progressive human greying.
When Luteolin was introduced, the difference was hard to ignore: more melanocyte stem cells remained, and the mice stayed darker for longer. Tested through both topical and oral delivery, the signal pointed the same way.

Luteolin is a key ingredient in Anti Grey 1.0. Explore the research behind the formula via the link in bio.

Most people take Ashwagandha only for stress. Few realise that stress can affect hair greying too.A 2021 Columbia Univer...
18/03/2026

Most people take Ashwagandha only for stress. Few realise that stress can affect hair greying too.

A 2021 Columbia University study was the first to quantitatively link psychological stress with hair greying in humans. In some cases, greying partially reversed when stress lifted.

Ashwagandha has been studied in the context of the same stress biology, which is part of why we include it in Anti Grey 1.0. Paired with Rhodiola, it becomes part of the formula’s stress-response approach.

Because hair colour is not a surface issue. It is a system.

🔗 hairlabs.ai
🔖 Rosenberg et al., eLife, 2021 · Chandrasekhar et al., Indian Journal of Psychological Medicine, 2012

Greying often starts earlier than people realise.◾️Melanocyte stem cells can begin losing their ability to migrate to wh...
17/03/2026

Greying often starts earlier than people realise.

◾️Melanocyte stem cells can begin losing their ability to migrate to where pigment is made.
◾️H₂O₂ can accumulate in the follicle, gradually affecting colour from within.
◾️Many products respond to the visible signs. Far fewer are designed around the biology behind them.

At this stage, the system is under pressure — but it has not failed.

We asked Danai, Clinical Trichologist, to assess Anti Grey 1.0 with exactly this question in mind. Here is her view:

"In clinical practice, most supplements marketed for grey hair focus on general hair health rather than the biology of pigmentation.
Hair Labs Anti Grey 1.0 instead targets pathways linked to melanin production and follicular ageing, reflecting a more mechanism-based approach.
As with any nutritional intervention, outcomes depend on individual physiology and consistency of use.
Approaches like this are generally most relevant for individuals in the early stages of greying or those seeking to slow further pigment loss, rather than reversing extensive established grey hair."
— Danai, Clinical Trichologist

Educational content only. Individual biology varies.

13/03/2026

Not just age. Not just genetics. Greying is linked to the complex biology of the follicle — from stem cells to oxidative stress and the signals that support pigment production. In this video, we briefly explain why modern science is increasingly looking at greying not as an inevitable “timer”, but as a process driven by specific cellular mechanisms.

Follow us if you want more clear explanations about the biology of greying, pigment, and modern hair research.

Inside the follicle, pigment depends on communication. Melanocyte stem cells respond to chemical instructions from the n...
12/03/2026

Inside the follicle, pigment depends on communication. Melanocyte stem cells respond to chemical instructions from the niche around them, including endothelin signalling through the EDNRB receptor. When that communication weakens, pigment-cell activity can weaken too.

This is part of the biology we study at Hair Labs: how colour is regulated through signalling, timing, oxidative balance, and cellular coordination.

🔬 Swipe to follow the signal.

10/03/2026

Do pigment cells really die?
Not exactly. They stall.

For years, greying was framed as a simple, one-way loss of pigment.
But NYU research suggests a more complex reality: pigment stem cells may not disappear entirely. Instead, they may lose the ability to properly respond to the signals around them.

In other words, the issue may not be cell loss alone.
It may be signal loss.

Japanese scientists have already identified antioxidants that may help restore this signalling and protect hair from further pigment decline.

At Hair Labs, we consolidate these findings through computational models to build a more intelligent approach to hair biology.

The future of hair care is not in masking greying.
It is in understanding the system behind it.

Greys reflect a shift in follicle biology. When the pigmentation system loses stability, colour doesn’t “disappear overn...
05/03/2026

Greys reflect a shift in follicle biology. When the pigmentation system loses stability, colour doesn’t “disappear overnight” — it gradually fades.

◾️The reserve of melanocyte stem cells becomes depleted.
◾️Oxidative stress (ROS/H₂O₂) can damage melanin and the enzymes involved in pigmentation.
◾️Cell-to-cell signalling weakens, disrupting the cycle that sustains pigmentation.

Next — in the carousel: how these three shifts connect into one system.
This framing was clearly articulated by Dr Mandy.

Educational content. Individual biology varies.

03/03/2026

Anti-greying was once just a world of myths and hair dyes.

But as we map the biological landscape of the hair follicle, we’re moving past the surface. We now know that greying is often driven by "chemical sparks" — oxidative stress that slowly drains the stem cell bank responsible for your hair’s colour.

In this video, we look at Luteolin.

This plant molecule isn’t a magic reversal; it’s a targeted shield. By protecting the pigment-producing cells before the damage becomes permanent, it offers a way to actually slow the greying clock at its source.

It’s a shift from hiding the silver to protecting the biology that’s already there.

Grey hair does not always begin with cell loss.Sometimes the problem is that the system supporting pigmentation is no lo...
02/03/2026

Grey hair does not always begin with cell loss.
Sometimes the problem is that the system supporting pigmentation is no longer working as it should.

A new wave of research suggests that:
◾️ pigment stem cells can become “stranded”,
◾️ stress-responsive signalling pathways can shift,
◾️ and oxidative load can build up.

In other words, this is not always a single breakdown.
It may be a disruption in the environment the follicle depends on to function properly.

That is why we view grey hair as a systems-level process.
Support your follicle environment early.

https://hairlabs.ai/products/anti-grey-1-0

Greying doesn’t happen because pigment “just disappears”. The follicle’s pigment system runs on signals — chemical messa...
28/02/2026

Greying doesn’t happen because pigment “just disappears”. The follicle’s pigment system runs on signals — chemical messages that keep melanocyte stem cells functional over time. When signalling weakens, pigment output fades.

Nagoya University researchers compared three closely related flavonoids — luteolin, hesperetin, and diosmetin — under the same experimental conditions.

“This result was surprising,” Professor Masashi Kato said. “While we expected that antioxidants may also have anti-greying effects, only luteolin, not hesperetin or diosmetin, demonstrated significant effects.”

In their report, they explain that the difference points to endothelin signalling — an essential communication pathway in follicle stem-cell biology. In other words: not “more antioxidants”, but the right signal staying online.

Source: Iida M. et al., Antioxidants (2024) 13(12):1549. DOI: 10.3390/antiox13121549.

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