31/03/2026
The following information comes from scientific researcher Caitlin Thompson.
Caitlin’s background is in neurobiology, with a focus on mood disorders & autoimmune conditions. In pursuit of her own healing, she has studied nutritional neuroscience and now supports others with chronic illness, autoimmune and psychiatric conditions through diet, nutraceuticals and modalities such as Kambo.
Caitlin is an independent researcher and is currently conducting some of the first human research in the field of Kambo.
Kambo: medicine or poison?
The Phyllomedusa bicolor secretion contains over 24 identified peptide compounds, alongside steroids, alkaloids and proteins.
Many demonstrate measurable medicinal effects and have attracted significant interest from pharmaceutical companies.
Over 70 patents exist on peptide analogues derived from these frog-based compounds, yet in many cases the naturally occurring peptides outperform synthetic versions.
Despite often being labelled a “poison,” there is little evidence of toxicity in mammals. One case report suggested a link to hepatitis, though this has been criticised due to the individual’s history of chronic alcoholism. Current peptide research does not indicate toxicity to the liver, kidneys, brain or other cells.
While there is substantial biochemical research on these peptides, there are very few animal studies and almost no human studies. Most existing research is based on animal models or in vitro studies using human cells. There are currently no studies examining the effects of individual peptides in humans, nor their combined effects as experienced in a Kambo session.
Caitlin Thompson, founder of Medicine Frog Kambo, is pioneering some of the first human research in this field.
If you feel called to explore Kambo, please get in touch ✨🐸✨
