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MFT Research and Innovation

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14/11/2025

A former Lord Mayor of Manchester, Councillor Yasmine Dar has become the 3,000th person in Greater Manchester to take part in a pioneering study aimed at understanding and tackling the higher rates of serious disease in South Asian people. 🎉

🧬 Genes & Health, supported by the NIHR (National Institute for Health and Care Research) (NIHR), is being carried out in several parts of England and making major advances in the prevention, diagnosis and treatment of disease.

🕌 Opportunities to take part, in places such as mosques and community events, have been made available by teams working on the study from Manchester University NHS Foundation Trust (MFT), the NIHR Research Delivery Network, Northern Care Alliance NHS Foundation Trust and Bolton NHS Foundation Trust.

👥 The study aims to recruit 100,000 people (16+) living in England by the end of 2028 and has already made important discoveries about the link between a person’s genes and the chance of disease, including identifying genetic factors specific to South Asian people that lead to earlier type 2 diabetes onset.

👇
https://research.cmft.nhs.uk/news-events/former-mayor-urges-fellow-south-asian-citizens-to-be-part-of-landmark-research-study

28/10/2025

🧬👶 A ground-breaking research study to help identify and treat rare genetic conditions in newborn babies has reached a major milestone with the recruitment of its 1,000th baby at Manchester University NHS Foundation Trust.

The Generation Study, led by Genomics England in partnership with NHS England, offers whole genome sequencing testing for newborn babies to help identify more than 200 rare genetic conditions that can be treated early in life.

Read more 👇
https://research.cmft.nhs.uk/news-events/pioneering-study-to-identify-rare-conditions-idenitifies-1000-babies-in-manchester

22/09/2025

💉 Three new studies aiming to improve the effectiveness of vaccinations for severe acute respiratory infections have launched in Manchester thanks to support from the National Institute for Health and Care Research (NIHR) Greater Manchester Commercial Research Delivery Centre (GM CRDC).

The three studies are the first to be delivered through the GM CRDC, one of 21 CRDCs across the UK, and aim to recruit patients who have been hospitalised with severe acute respiratory infections.

The studies will enable researchers to evaluate how COVID-19 and Respiratory Syncytial Virus vaccines perform outside of clinical trials and across diverse populations. This will provide essential real-world evidence into the degree of protection vaccines offer against serious respiratory illness, hospitalisation, and healthcare burden.

Read more 👇
https://research.cmft.nhs.uk/news-events/greater-manchester-commercial-research-delivery-centre-announces-first-studies

19/09/2025

👩‍⚕️ Sue Stockdale, Advanced Nurse Practitioner (ANP) at the National Institute for Health and Care Research (NIHR) Manchester Clinical Research Facility, discusses her career journey to become a Principal Investigator, the importance of the NIHR Principal Investigator Pipeline Programme in this achievement, and why she would highly recommend this research path to other ANPs.

✏️ Read Sue’s blog:
https://research.cmft.nhs.uk/news-events/from-advanced-nurse-practitioner-to-principal-investigator

12/09/2025

🤝 Manchester University NHS Foundation Trust (MFT) has strengthened its partnership with medical technology company Medtronic, with an agreement to explore new treatments using robotic surgery and artificial intelligence.

It forms part of a new Research, Development and Innovation collaboration agreement which will accelerate the development of medtech solutions that could benefit patients and healthcare providers globally.

Opportunities will also be provided for MFT’s existing hosted infrastructure including the NIHR HealthTech Research Centre in Emergency and Acute Care, with the strategic focus on utilising new technology to meet the big 3 shifts from the NHS 10 Year Plan.

Read more 👇
https://research.cmft.nhs.uk/news-events/mft-and-medtronic-partner-to-accelerate-medtech-innovations-across-the-nhs

11/08/2025

A new once-daily cystic fibrosis (CF) treatment trialled in Manchester has been approved for NHS use, following a recommendation made earlier this month by the National Institute for Health and Care Excellence (NICE).

Clinical trials delivered at the National Institute for Health and Care Research (NIHR) Manchester Clinical Research Facility (CRF), part of Manchester University NHS Foundation Trust (MFT), have shown the new triple therapy Alyftrek® to be at least as effective as current drug Kaftrio® at improving lung function for people aged over 12 with CF caused by a specific gene (F508del) mutation.

Cystic Fibrosis is a rare genetic condition affecting more than 10,000 people in the UK. It causes thick, sticky mucus to build up in the lungs, digestive system and other organs causing a wide range of challenging symptoms. The condition is caused by reduced quantity and/or function of the CF transmembrane conductance regulator (CFTR) protein that regulates levels of sodium and chloride in cells.

Professor Alex Horsley, Consultant at the Manchester Cystic Fibrosis Centre, was the Lead Investigator. Adam Higson, 45, from Rochdale was diagnosed with CF in 1980, when he was 11-months old. He took part in the clinical trial at the NIHR Manchester CRF at Wythenshawe Hospital.

Read more👇
https://manchestercrf.nihr.ac.uk/latest-news/life-changing-cystic-fibrosis-treatment-trialled-in-manchester-now-approved-for-nhs-use/

31/07/2025

Congratulations to Molly Bennett, Senior Clinical Research Practitioner, Research and Innovation (R&I), at Manchester University NHS Foundation Trust, on receiving her R&I Cultural Ambassador award.

Molly has been recognised for excelling in the category of Vision and Values. 👏

15/07/2025

Congratulations to R&I colleagues on receiving their awards following the recent Manchester University NHS Foundation Trust (MFT) Clinical Quality Assurance inspections:

🌟 NIHR Manchester Clinical Research Facility (CRF) at Royal Manchester Children's Hospital - Gold Accreditation
🌟 The Midwifery Research team at Saint Mary’s Hospital - Silver Accreditation

Janette Dunkerley, Assistant Chief Nurse for R&I presented the award certificates. Well done to both teams! 👏

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