28/01/2026
I'm not sure this paper tells us anything new, but it does validate those women who suffer the frustrating effects of menopause on cognition. https://www.cam.ac.uk/research/news/menopause-linked-to-loss-of-grey-matter-in-the-brain-poorer-mental-health-and-sleep-disturbance
I can struggle with word-finding on occasion, but that tends to be when I'm multi-tasking or under pressure. Again, we know that long-term stress negatively effects all health, in both men and women, and is certainly a key player in exacerbating menopausal symptoms.
So what's the answer? Throwing our arms in the air and shrieking "we're doomed!" is not it.
As with most health declines, there are things we can proactively do. And this brings me to another study, over 10 years ago and before the focus on menopause: that muscle strength, particularly of the lower legs, can help offset grey matter decline in the brain.
"Leg power predicts both cognitive ageing and global brain structure, despite controlling for common genetics and early life environment shared by twins. Interventions targeted to improve leg power in the long term may help reach a universal goal of healthy cognitive ageing." https://karger.com/ger/article/62/2/138/149063/Kicking-Back-Cognitive-Ageing-Leg-Power-Predicts
Exercise and movement, particularly when done outdoors, is beneficial for overall brain health, improving mood and reducing stress. Loss of muscle mass can start in your '30s, accelerating after the age of 60, with a loss of up to 8% of muscle mass per decade. So use it or lose it.
And as I've said before, if exercise was a pill, it would be prescribed to everyone.
Menopause is linked to reductions in grey matter volume in key brain regions as well as increased levels of anxiety and depression and difficulties with sleep,