DrA-Says

DrA-Says Doctor Ahmed MBBS MRCGP BSc

Fibromyalgia /nervous system recovery 👇

https://mendcollective.online

Private appointments 👇

https://mendclinic.uk
(5)

The "Unholy Trinity": ADHD, Fibro, & MCAS It’s not a coincidence. It’s a biological pathway. They are all linked. Full a...
07/12/2025

The "Unholy Trinity": ADHD, Fibro, & MCAS
It’s not a coincidence. It’s a biological pathway. They are all linked. Full article in comments.

05/12/2025

This is much more common than we think.

Microdosing GLP-1s for MCAS?Why we’re using LDN and peptides to treat "The Storm" (not just allergies). Full article in ...
05/12/2025

Microdosing GLP-1s for MCAS?
Why we’re using LDN and peptides to treat "The Storm" (not just allergies). Full article in comments

Your labs are normal." (Why they are wrong)Why standard testing misses MCAS 90% of the time. Full article in comments
04/12/2025

Your labs are normal." (Why they are wrong)
Why standard testing misses MCAS 90% of the time. Full article in comments

Does your brain fog feel... physical? 🧠🔥If you live with the “Trifecta” (hEDS, POTS, MCAS) and are also Neurodivergent (...
01/12/2025

Does your brain fog feel... physical? 🧠🔥
If you live with the “Trifecta” (hEDS, POTS, MCAS) and are also Neurodivergent (ADHD or Autistic), your bad brain days might actually be an immune reaction.
We often treat these things separately:
💊 Psychiatrist for the focus.
🦴 Rheumatologist for the joints.
🤧 Immunologist for the allergies.
But in your body, they are all connected.
The Loop:
When your Mast Cells degranulate (react) in your brain, it causes neuroinflammation. This literally slows down cognitive processing.
Combine that with the sensory nightmare of loose hEDS joints and sensitive MCAS skin, and your Neurodivergent nervous system hits “Overload” much faster.
The Takeaway:
If your ADHD meds aren’t working, or your sensory tolerance is at zero... check your inflammation., screen for MCAS Are you in a flare?
Sometimes the best thing you can do for your mental health is put on compression socks, take an antihistamine, and rest.

The hEDS, MCAS, & ADHD "Feedback Loop"Why your loose joints and immune reactions are hijacking your focus (and how to br...
01/12/2025

The hEDS, MCAS, & ADHD "Feedback Loop"
Why your loose joints and immune reactions are hijacking your focus (and how to break the cycle). Full article in comments

Mast Cells live deep inside connective tissue.In hEDS, tissue is lax and unstable.Movement over-stretches this fragile m...
29/11/2025

Mast Cells live deep inside connective tissue.

In hEDS, tissue is lax and unstable.

Movement over-stretches this fragile matrix.

This physical “pull” can signal Mast Cells to degranulate and release histamine.

Symptom overlap
🧠 Neurological: Brain fog & neuroinflammation
🍽️ Gastro: Dysmotility + food-triggered reactions
🖐️ Dermatological: Dermatographia isn’t fragile skin —
  it’s a histamine response to pressure

Potential treatment (brief summary likely more complex)
Stabilize: H1/H2 blockers + Mast Cell stabilizers

Environment: Limit vibration (car rides, heavy machinery)
  — physical motion can trigger Mast Cells

Excipients: Reactions often come from fillers/dyes, not the medication itself

Normal tryptase does NOT rule out MCAS

Tryptase measures burden (cell count), not always activation

Ask your doctor about the “Consensus-2” diagnostic criteria

I try to help people who have this overlap, please check link on profile if you would like a appointment.

Why your loose joints trigger allergic reactionsWhy collagen laxity causes Mast Cell Degranulation. Full article in comm...
29/11/2025

Why your loose joints trigger allergic reactions
Why collagen laxity causes Mast Cell Degranulation. Full article in comments

28/11/2025

Of course avoiding food triggers is key, but it needs professional oversight and any histamine /mcas concerns really need to be addressed before any dietary changes made.

The "Safe Food" Paradox: Why Restricting Is Making You SickerYou cannot heal a body that thinks it is starving. Here is ...
28/11/2025

The "Safe Food" Paradox: Why Restricting Is Making You Sicker
You cannot heal a body that thinks it is starving. Here is the biological reason why. Full article in comments

"But My Blood Work Was Normal..."Why standard labs miss the "invisible fire" of Mast Cell Activation Syndrome. Full arti...
27/11/2025

"But My Blood Work Was Normal..."
Why standard labs miss the "invisible fire" of Mast Cell Activation Syndrome. Full article in comments

Why You Look 6 Months Pregnant (It’s Not Just Endo)The surprising connection between histamine, bloating, and pelvic pai...
26/11/2025

Why You Look 6 Months Pregnant (It’s Not Just Endo)
The surprising connection between histamine, bloating, and pelvic pain. Full article in comments

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