Nottingham Respiratory Research Unit

19/07/2025

We have recently commenced a new study sponsored by Avalyn Pharma and led at Nottingham University Hospitals by Dr Sy Giin Chong.

New Placebo-Controlled Study of Inhaled Pirfenidone in Progressive Pulmonary Fibrosis.

The Sponsor is developing AP01 (also referred to in this document as the “study drug”) for use in the treatment of Progressive Pulmonary Fibrosis. AP01 is an experimental drug that may slow your PPF symptoms. You will inhale the study drug using the eFlow Nebuliser System.

26/06/2025

New Study now commenced led by Dr Helen Barr.

Evaluating the Safety, Tolerability, and Biodistribution of RCT2100 with Single-Ascending Doses in Healthy Participants and Multiple-Ascending Doses and Proof-of-Concept in Participants with CF

Evaluating the Safety, Tolerability, and Biodistribution of RCT2100 with Single-Ascending Doses in Healthy Participants and Multiple-Ascending Doses and Proof-of-Concept in Participants with CF

03/03/2025

We are thrilled to share that our research lung physiologist Paula Almeida has been selected as the Expert from the United Kingdom to join the World Health Organization's Asthma Guidelines Development Group (Asthma GDG).

This recognition acknowledges her 17 years of dedication to the study of respiratory physiology and global asthma care. She is particularly proud to be the only Physiotherapist in the group.

Paula tells us “It is a privilege to be part of this exceptional group of Global Experts.”

If you are interested in exploring more, you can find the brief biographies of the group members on the WHO CRD webpage:

The most common chronic respiratory diseases are asthma and chronic obstructive pulmonary disease (COPD).

28/02/2025

Well done Suzanne & Hollie
https://www.facebook.com/share/p/185G2MrmVu/?mibextid=wwXIfr

Suzanne Swann and Hollie Gorensweigh at the NIHR Nottingham Biomedical Research Centre stand at QMC main entrance this morning, supporting Rare Disease Day and increasing awareness. Thank you and hope you had a great time!

28/02/2025

Editorial: PRISm- prognostic, preventable and treatable?
https://thorax.bmj.com/content/early/2025/02/20/thorax-2024-222923

28/02/2025

Today is Rare Disease Day.

The Nottingham Biomedical Research Centre (BRC) is improving the health of millions of people with common diseases like asthma, depression and arthritis.

24/12/2024

Day 12 of our 12 days of Christmas at NRRU:
Our final day is a thank you for everyone's continued support. We look forward to bringing our research through to 2025 and beyond. Merry Christmas and a fantastic New Year!

23/12/2024

Day 11 of our 12 days of Christmas at NRRU:
We tried desperately to somehow fit one of the numbers to this but alas we couldn't but fortunately Dr. Lim still gets a day dedicated to himself. Dr. Wei Shen Lim worked on COVID-19 and advised the UK government during the pandemic for which he greatly deserves his honorary knighthood.

22/12/2024

Day 10 of our 12 days of Christmas at NRRU:
Day 10 is for for the year we opened our research unit. On the 9th of June 2010 we opened our doors for the first time. We still have some of our founding members of staff including Tina, Norma, Katherine and Hellen and we're ever evolving and improving.

21/12/2024

Day 9 of our 12 days of Christmas at NRRU:
Day 9 is for the £9,000,000 secured by Simon Johnson for the new national research centre. This new centre involving researchers from the NIHR Nottingham Biomedical Research Centre and led by the University of Nottingham will accelerate improved tests, treatments and potentially cures for thousands of people living with rare respiratory diseases.

20/12/2024

Day 8 of our 12 days of Christmas at NRRU:
Day 8 is for our 8 COPD studies opened this year lead by Prof. Charlotte Bolton and Dr. Sam Kemp. Our C-FIND study is the first of its kind in Nottingham to utilise the mobile research unit. The study researches whether a lung check, done in the community using a mobile clinical area, of people at risk of COPD is acceptable and useful.

19/12/2024

Day 7 of our 12 days of Christmas at NRRU:
Day 7 is for the 7 interstitial lung disease and idiopathic pulmonary fibrosis studies being lead by Dr. Gauri Saini and the team of research nurses. This rare chronic lung disease which causes irreversible scarring and research into this area is vital for understanding new treatments.