08/10/2025
You may have heard about Methylene Blue, but do you know what it is and what it does? 🤔
Let us explain…
As an organic dye, it was first used in 1876 as a textile dye, yet within a few years scientists began using it to stain microorganisms to help diagnose infections.
Then, in 1891, it was found to treat malaria, thus making it the first synthetic compound ever used as an antiseptic in clinical therapy and the first antiseptic dye to be used therapeutically.
Fast-forward to present day and it’s now commonly used as a medication to treat methemoglobinemia - a rare blood condition that affects how red blood cells deliver oxygen throughout the body - along with gonorrhoea, bladder infections, Candida infections, and even Lyme disease, thanks to its disinfectant, anti-viral properties.
But that’s not all…
🫀It’s also been shown to inhibit the effects of nitric oxide (NO), inducing hemodynamic effects in people with vasoplegic syndrome - vasodilative shock that can present as severe hypotension, tachycardia, altered cardiac output, and reduced pulmonary pressure.
🧠It additionally has neuroprotective effects, due to its ability to pe*****te the blood-brain barrier and reduce oxidative stress, thus, researchers have been investigating it for the treatment of neurological disorders, such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease.
🔋And, as it’s highly soluble in both water and organic solvents, it has the capacity to freely enter cells and various organelles, including the mitochondria, within which it helps facilitate the movement of electrons whilst reducing the production of superoxide molecules - helping to slow cellular aging, including in the brain, along with maintaining energy levels and fighting fatigue.
🔬In conclusion, Methylene Blue has been shown to have diverse therapeutic potential, spanning from cognitive enhancement to anti-aging effects, however, as research is still on-going, we highly recommend consulting a practitioner before taking it.
❌And those who are pregnant, breastfeeding, on serotonin increasing medications (such as SSRIs and SNRIs), or have renal issues should avoid supplementation completely.