Health Research Southampton

14/11/2025

How could digital solutions help tackle blood shortages around the globe? 🌍

Meet Honghui Shen, a PhD researcher at the NIHR Southampton Biomedical Research Centre and University of Southampton. He's developing an app to connect hospitals with donors in real time - boosting emergency care and saving lives.

Read more 👉 https://southamptonbrc.nihr.ac.uk/post/supporting-emergency-blood-donation-in-rural-ghana-meet-honghui-shen

14/11/2025

November is .

is often diagnosed late, when treatment options are limited.

Our SAFE-D trial is evaluating a blood test, developed by ClearNote Health, which aims spot the very earliest signs of the developing. The trial uses blood samples from people with a recent diagnosis of type 2 diabetes – a known risk factor and potential sign or symptom of pancreatic cancer.

Find out more about the study - https://safe-d.uk/



University Hospital Southampton NHS Foundation Trust, Health Research Southampton, University of Southampton, University of Southampton Medicine, Cancer Research UK, Pancreatic Cancer UK, Pancreatic Cancer Action

10/11/2025

👶 New hope for babies with suspected meningitis

The BOBBi trial will see if steroids can help more babies under three months old survive without long-term health problems.

Over 1,000 babies will take part, including at University Hospital Southampton NHS Foundation Trust 👇 https://research.uhs.nhs.uk/news/babies-with-suspected-meningitis-to-receive-steroids-in-new-trial

07/11/2025

🎉 Huge congratulations to Professor Denny Levett on her appointment as Director of the Centre for Perioperative Care!

Denny is a leader in perioperative and critical care medicine at the University of Southampton and University Hospital Southampton NHS Foundation Trust. She is a theme co-lead at the NIHR Southampton Biomedical Research Centre.

We’re proud to see expertise shaping national care. 👏

🔗 https://cpoc.org.uk/news/professor-denny-levett-appointed-incoming-director-centre-perioperative-care

07/11/2025

Turning purple for .

Our team is helping to raise awareness of the vital need for more into the of pancreatic cancer.

is the 10th most common cancer in the UK but the 5th most common cause of cancer death. This is because many patients are diagnosed late, when the is already at an advanced stage and treatment options are limited.

Our SAFE-D study is evaluating whether a new blood test can spot the signals of pancreatic cancer at an early stage when it is more treatable and will use blood samples from people with a recent diagnosis of type 2 – a known risk factor and potential sign or symptom of pancreatic cancer.

Find out more about the SAFE-D study here - https://safe-d.uk/



Pancreatic Cancer Action Network, Pancreatic Cancer UK, Cancer Research UK, Health Research Southampton, University of Southampton Medicine, University of Southampton

06/11/2025

“We hope this can greatly improve the lives of children with and their families,” says Professor Cathy Hill.

BBC's David Allard visited University Hospital Southampton NHS Foundation Trust this week to learn about Sleep Buddy.

Almost two-thirds of children with ADHD experience sleep problems. This can make the symptoms of ADHD worse, affecting children’s behaviour and schoolwork, and quality of life for the whole family.

Researchers at UHS, the University of Southampton and Southampton Clinical Trials Unit are leading a national trial to see if a digital support website can help them sleep better.

Watch BBC South Today to find out more 🎥

Read David's report, 'Could a website help children with ADHD sleep?' here 👉 https://www.bbc.co.uk/news/articles/cyv85n825j9o

06/11/2025

UHS is leading a groundbreaking trial of a digital support tool designed to help children with ADHD improve their sleep.

Developed by experts and parents, Sleep Buddy offers practical advice, sleep plans and guidance tailored to the unique challenges faced by children with ADHD.

📊 Almost two thirds of children with ADHD experience sleep problems. These include finding it hard to get to sleep at bedtime, waking in the night or waking up early in the morning.

🏥 Researchers UHS, the University of Southampton and Southampton Clinical Trials Unit have been working with parents and carers of children with ADHD to develop Sleep Buddy. Families are now being invited to help researchers test to how well Sleep Buddy works in a large trial.

🔗 Find out more: https://www.uhs.nhs.uk/whats-new/press-releases/sleep-buddy-trial-aims-to-help-children-with-adhd-and-their-families

06/11/2025

05/11/2025

Tackling infections and antibiotic resistance 🤧🦠

Prof Tristan Clark from the University of Southampton and University Hospital Southampton NHS Foundation Trust is one of six new outstanding leaders chosen to address urgent health challenges.

He has been appointed as an NIHR Research Professor 👏

🔗 https://research.uhs.nhs.uk/news/new-nihr-research-professor-to-help-tackle-antibiotic-resistance

31/10/2025

Over 9⃣0⃣0⃣ people have joined a study to help fight serious viral infections like flu and RSV 💙👏

The national UNIVERSAL study is exploring how and when patients may progress to more serious disease.

This could help develop effective antiviral treatments to combat these infections.

It is sponsored by University Hospital Southampton NHS Foundation Trust and supported by Southampton Clinical Trials Unit.

Pedro Rodrigues, senior trial manager, said: “Our goal is to make real-world impact, move from sickness to prevention and from hospital care to community-based care, protecting patients and strengthening our NHS when it’s needed most.”

🔗 https://research.uhs.nhs.uk/news/research-study-reaches-milestone-to-help-tackle-severe-viral-infections

30/10/2025

🧠 Meet the neurodegenerative research team at University Hospital Southampton NHS Foundation Trust!

They are supporting studies into dementia and other neurological conditions.

Together with participants, families and researchers, they are driving innovation in diagnosis, treatment and care 👏

Recently, UHS was the first NHS site to open for recruitment for the TRONTIER 2 study. This is testing how well and how safely the drug trontinemab works for people who have early symptoms of Alzheimer's disease.

"As one of the country’s leading dementia trial delivery sites, we are delighted that we have been able to move rapidly to open the study," said Professor Christopher Kipps, "giving people affected by dementia the chance to take part in research that is shaping the treatments of tomorrow.”

29/10/2025

The solutions needed to overcome infection and antimicrobial resistance are complex 🏥😷

They require collaborative and coordinated research.

Scientists from Southampton are at the heart of a new national network backed by the National Institute for Health and Care Research 👏

The new Translational Research Collaboration (TRC) is hosted by Imperial College London. It joins six other TRCs already working on big health challenges.

🔗 https://research.uhs.nhs.uk/news/southampton-joins-uk-wide-effort-to-fight-infections-and-drug-resistance