NIHR Southampton Clinical Research Facility

07/11/2025

Turning purple for .

Our team is helping to raise awareness of the vital need for more into the of pancreatic cancer.

is the 10th most common cancer in the UK but the 5th most common cause of cancer death. This is because many patients are diagnosed late, when the is already at an advanced stage and treatment options are limited.

Our SAFE-D study is evaluating whether a new blood test can spot the signals of pancreatic cancer at an early stage when it is more treatable and will use blood samples from people with a recent diagnosis of type 2 – a known risk factor and potential sign or symptom of pancreatic cancer.

Find out more about the SAFE-D study here - https://safe-d.uk/



Pancreatic Cancer Action Network, Pancreatic Cancer UK, Cancer Research UK, Health Research Southampton, University of Southampton Medicine, University of Southampton

06/11/2025

“We hope this can greatly improve the lives of children with and their families,” says Professor Cathy Hill.

BBC's David Allard visited University Hospital Southampton NHS Foundation Trust this week to learn about Sleep Buddy.

Almost two-thirds of children with ADHD experience sleep problems. This can make the symptoms of ADHD worse, affecting children’s behaviour and schoolwork, and quality of life for the whole family.

Researchers at UHS, the University of Southampton and Southampton Clinical Trials Unit are leading a national trial to see if a digital support website can help them sleep better.

Watch BBC South Today to find out more 🎥

Read David's report, 'Could a website help children with ADHD sleep?' here 👉 https://www.bbc.co.uk/news/articles/cyv85n825j9o

30/10/2025

🧠 Meet the neurodegenerative research team at University Hospital Southampton NHS Foundation Trust!

They are supporting studies into dementia and other neurological conditions.

Together with participants, families and researchers, they are driving innovation in diagnosis, treatment and care 👏

Recently, UHS was the first NHS site to open for recruitment for the TRONTIER 2 study. This is testing how well and how safely the drug trontinemab works for people who have early symptoms of Alzheimer's disease.

"As one of the country’s leading dementia trial delivery sites, we are delighted that we have been able to move rapidly to open the study," said Professor Christopher Kipps, "giving people affected by dementia the chance to take part in research that is shaping the treatments of tomorrow.”

17/10/2025

A new UK-wide clinical trial led by UHS and primary care services is testing whether the nasal flu vaccine can be offered to one-year-old children.

The FluSNIFF study is inviting families to take part at 100 GP practices and three hospitals across the country.

Flu can be serious for young children, and this needle-free vaccine – already used safely in older children – could make protection easier and more accessible.

It could mean all one-year-olds get flu protection in future winters.

If your child is aged 12 to 23 months and your GP is participating, you may be invited to join the study.

🔗 Find out more: https://www.uhs.nhs.uk/whats-new/press-releases/flu-vaccine-spray-trial-launches-for-children-aged-…

10/10/2025

New protection for premature babies this winter 💙

Thank you to the many families who took part in the Harmonie study to help realise this life-changing milestone.

Baby Elowyn is a new star on BBC News 👶🌟

Premature babies are being offered new protection against RSV this winter.

BBC Hampshire & Isle of Wight met Elowyn and parents, Molly and Jack, as they reported on the new jab at our Princess Anne Hospital.

The immunisation is now available following years of clinical research, including an international trial co-led by experts at UHS.

Researchers are thanking the many families that took part in the Harmonie study across the south to help realise this life-changing milestone.

Read more 🔗 https://www.bbc.co.uk/news/articles/c4g9ned0526o

10/09/2025

We want to help inspire young people to pursue jobs in healthcare and research 🏥🌟

Aspiring medics gained valuable hands-on experience at this year’s LifeLab summer school.

The two-day course included an introduction to research by Lead Matron Lisa Berry, as well as a tour of our facility at University Hospital Southampton NHS Foundation Trust.

The summer school is for students in years 9 to 11 interested in studying medicine at university.

Read more: https://www.southamptoncrf.nihr.ac.uk/post/summer-school-inspires-young-people-to-pursue-jobs-in-healthcare-and-research

04/09/2025

03/09/2025

07/08/2025

Are you aged 18 to 55 years old and in good health?

You may be eligible to take part in the BiVISTA study at University Hospital Southampton NHS Foundation Trust to test a new vaccine against typhoid and paratyphoid A fever.

All participants will be reimbursed up to £4,410.

ℹ️ More information: https://www.ovg.ox.ac.uk/studies/bivista/southampton

16/07/2025

1️⃣,0️⃣0️⃣0️⃣ babies have joined an eye screening study at University Hospital Southampton NHS Foundation Trust!

Researchers are trialling a new way to diagnose cataracts in newborns. The condition affects about one in 3,000 babies and can lead to blindness if left untreated.

We are so proud of our incredible research nurses and midwives who made this milestone possible 👏

🔗👉 https://www.southamptoncrf.nihr.ac.uk/post/southampton-recruits-1-000-babies-for-newborn-eye-screening-study