LSI Silderma is a specialized pharmaceutical company focusing on the development and commercialization of cosmeceuticals for dermatological diseases.
LSI in brief
A passion for skin physiology
Founded in 1999 in London by Dr. Christian Diehl, LSI is a pharmaceutical company focused on the area of dermatology, plastic surgery and aesthetic medicine. We intend to develop cosmeceuticals and nutraceuticals oriented to the treatment and prevention of skin diseases and skin aging. Our goal is to offer healthcare professionals new, innovative, efficient and safe alternatives for prescriptions.
• LSI, an active player in dermatology, plastic surgery and aesthetic medicine.
• An international presence in over 70 countries.
• 3 manufacturing sites (2 in Switzerland and 1 in Ecuador).
• 1 operational base in Switzerland.
• 5% of net sales dedicated to R&D.
• Founded in 1999 in London (UK). Our commitment
For more than 15 years, LSI has been dedicated to develop and market innovative, efficient and safe products aimed at the improvement of various skin conditions. Our goal is making these products accessible to an ever growing number of physicians around the world, for a better health and well-being of their patients. Dr. Christian Diehl, truly passionate about skin
Dr. Christian Diehl is a pharmacologist who was ever passionate about skin physiology, and since 1980 he decided to focus on his passion. He created successively various successful companies, all of them in the same area, and besides was a consultant for various multinational pharmaceutical companies. Nowadays he is exclusively dedicating more than 35 years of professional expertise to LSI.
13/02/2026
A new generation in melasma care.
Targeted & Advanced Treatment
TRANACIX®️ Cream SPF 20
Formulated with 3% Tranexamic Acid, a key active for melasma.
Helps reduce pigmentation and vascular activity.
SPF 20 protects against UV-induced pigmentation
triggers.
Safe, effective, and suitable for long-term use.
Targeting melasma at its source.
06/02/2026
AKNIX® fits perfectly into modern medical acne care. 🧴🩺
It is designed to support treatments, not replace them, and to manage acne long-term.
European and American dermatology guidelines highlight the importance of: 🇪🇺🇺🇸
🔹 Early use of medicated dermo cosmetics
🔹 Supportive skincare alongside treatments
🔹 Maintenance to help prevent relapse
AKNIX® follows this approach, making acne care simpler, effective, and sustainable for both patients and professionals. ✨🔬
02/02/2026
✨ A smarter approach to acne care ✨
It represents a new way to manage acne:
more effective, more respectful of the skin,
and designed for long-term results.
AKNIX® goes beyond classic cosmetic solutions,
using targeted active ingredients that work at the root of acne,
while remaining well-tolerated and suitable for daily, long-term use.
This is care guided by medical logic,
not a quick cosmetic fix.
A smarter, more complete answer to acne —
especially when other solutions fall short.
👉 Discover the AKNIX® line
👉 Consult your dermatologist
29/01/2026
AKNIX® works where acne really begins, inside
the skin.
Research shows that acne is strongly influenced
by two internal messengers that stimulate oil
production.
When they are overactive, pores produce too
much oil, and breakouts keep comino back.
AKNIX® is unique because it targets both of these
drivers at the same time, helping to:
☑️Reduce excess oil
☑️ Calm overactive oil glands
☑️ Limit persistent and recurring acne
The result?
More balanced skin, fewer relapses, and
long-term acne control, not just temporary fixes.
29/01/2026
AKNIX® works where acne really begins, inside
the skin.
Research shows that acne is strongly influenced
by two internal messengers that stimulate oil
production.
When they are overactive, pores produce too
much oil, and breakouts keep coming back.
AKNIX® is unique because it targets both of these
drivers at the same time, helping to:
☑️Reduce excess oil
☑️ Calm overactive oil glands
☑️ Limit persistent and recurring acne
The result?
More balanced skin, fewer relapses, and
long-term acne control, not just temporary fixes.
27/01/2026
Diabetic skin deserves care that truly understands diabetes…
For over 25 years, at LSI we’ve studied the skin — and how diabetes changes its needs.
DIABDERMIX combines science and nature to support hydration, comfort, and skin balance in diabetic skin.
🌿Natural moisturizers, soothing actives, and antioxidants work together to protect skin, feet, and nails affected by diabetes.
Designed with carefully selected ingredients, clinically tested for safety and effectiveness.
👉 Consult your healthcare professional to learn more about diabetic skin care.
👉 Share this with someone living with diabetes who may find it helpful.
22/01/2026
One line. Complete care. Designed for skin in diabetes.
Skin, feet, and nails are all affected by diabetes — and all need specific attention.
The DIABDERMIX Line was created to answer these needs with consistent, daily care that
fits naturally into your routine.
Taking care of your skin shouldn’t be complicated.
It should help you stay focused on what truly matters: balance, control, and living fully.
👉 DIABDERMIX. Care designed for skin, feet, and nails in diabetes.
16/01/2026
Diabdermix Line combines science and nature, with carefully selected active ingredients that support hydration, comfort, and balance in diabetic skin.
🌿 Natural moisturizers such as shea butter, macadamia oil, coconut oil, polyglutamic acid (PGA), and olive oil wax help reinforce the skin barrier.
✨ Soothing and anti-inflammatory actives like hyperoxygenated olive oil (HOFA) and bergamot calm and support skin recovery.
🛡️ Antioxidants including silver vine extract, ume extract, noni fruit juice, and superoxide dismutase (SOD) extracted from green tomato help protect and soothe the skin.
DIABDERMIX is designed to care for skin, feet, and nails affected by diabetes.
👉 Diabetic skin care backed by research, nature, and experience.
12/01/2026
Being diagnosed with diabetes often means focusing on treatments and daily routines.
What’s often overlooked is that diabetes also affects your skin.
Diabetic skin needs specific, targeted care.
With over 25 years of expertise in skin health, LSI developed DIABDERMIX after studying how diabetes impacts the skin, feet, and nails, selecting active ingredients that help protect and support them.
✨ DIABDERMIX — care designed for diabetic skin, from the moment of diagnosis.
👉 Because your skin deserves care that understands diabetes.
11/12/2025
2026 arrives with promises of renewal, hydration, firmness, and even-toned, healthier skin.
A year to feel confident, cared for, and supported by science-driven skincare.
✨ Get ready for what’s coming.
New content, new insights, and new ways to connect with the TRANACIX & BIOTOPIX brands are on the way.
Let’s welcome a year of well-being, innovation, and radiant skin.
Stay connected — the best is yet to come.
10/12/2025
Celebrating all the new things this upcoming year will bring…
2026 will be for Celebration!
A year that arrives with more hydration, relief, firmness and a unified tone for flawless, healthy skin.
Stay Tuned!
And get ready, TRANACIX & BIOTOPIX will bring new social media interactions.
Coming soon!
Address
Unit 3D, North Point House. Business Park, New Mallow Road Cork T23AT2P
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Founded in 1999, LSI SILDERMA is a pharmaceutical company focused on the areas of dermatology, plastic surgery and aesthetic medicine. We intend to develop cosmeceuticals and nutraceuticals oriented to the treatment and prevention of skin diseases and skin aging. Our goal is to offer healthcare professionals new, innovative, efficient and safe alternatives for prescriptions.
Una pasión para la fisiología de la piel
Creada en 1999 en Londres, LSI SILDERMA es una compañía farmacéutica concentrada en las áreas de dermatología, cirugía plástica y medicina estética. Nos dedicamos a desarrollar cosmecéuticos y nutracéuticos dirigidos al tratamiento y la prevención de enfermedades de la piel y al envejecimiento cutáneo. Nuestra meta es brindar a los profesionales de la salud alternativas innovadoras, de eficacia comprobada y seguras para sus prescripciones.
Une passion pour la physiologie de la peau
Fondée en 1999 à Londres, LSI SILDERMA est une entreprise pharmaceutique orientée vers la dermatologie, la chirurgie plastique et la médecine esthétique. Nous concentrons nos efforts sur le développement de cosméceutiques et nutraceutiques destinés au traitement et à la prévention des maladies de la peau et du vieillissement cutané. Notre objectif est d’offrir aux professionnels de la santé des alternatives innovantes, à l’efficacité prouvée et sûres pour leurs prescriptions.
LSI SILDERMA
Unit 3D, North Point House.
Business Park, New Mallow Road. Cork T23AT2P – IRELAND.