03/02/2019
MTHFR explained reasonably simply.........
The MTHFR gene codes for the enzyme (also called MTHFR) which converts 5,10-Methylene folate to Methyl-folate (the, so called, 'active form).
This is the only way the body can make methyl-folate, which is needed to donate the 'methyl' to vitamin B12 an important step in METHYLATION ... so it's quite important 😉
If you are in the approx 33% of people (Caucasians) who have a particular variant called C677T, the gene and enzyme can be up to 65% less efficient, POTENTIALLY resulting in less methyl-folate, and POTENTIALLY impacting Methylation, and POTENTIALLY contributing to heart disease, infertility, autism, dementia, depression and many types of cancer.
Note the word POTENTIAL 😉
There are thousands of facebook, instagram and websites dedicated to explaining the terrible effects of MTHFR SNPs and blaming them for everything.
HOWEVER the good news is that the negative effects of MTHFR can be supported and offset through 🥁🥁🥁
🎉🎉🎉NUTRITION!!! 🍽️If you have an MTHFR C677T SNP you should ensure good intake of folate - ideally from foods such as green leafy veg 🥗, broccoli, citrus 🍋, beans, mushrooms 🍄 - and other B vitamins - B2, B3 and B6 which act as co-factors. And ensure B12 is optimal - otherwise the methyl-folate will go no-where (known as the methyl-trap).
If you have increased needs, such as pregnancy, high mental or physical stress, you MAY benefit from supplementing with methyl-folate directly, for a limited time. Take advice from a qualified nutritional therapist
Key take aways:
Genes are not your destiny
An MTHFR C677T SNP is not the devil
Good nutrition can compensate
Supplementation may help
Work with a nutritional therapist
If you want to learn more come along to Lifecode Gx Methylation Seminar on Sunday 10th February, Royal Society of Medicine in London.
LINK IN BIO or at buff.ly/2WEa8kD