CRYSTAL3Project

CRYSTAL3Project Commercial & Research Opportunity for Cysteinyl Leukotriene Signalling in Ocular & CNS Dysfunction,

CRYSTAL3 is an international consortium (10 partners in 7 countries, led by University College Dublin) funded by EU Horizon 2020 with €887,800 to research on cysteinyl leukotrienes (CysLTs), a relatively unexplored cellular signalling pathway, seen across a range of human diseases. The CRYSTAL3 consortium investigates the links between CysLT signalling and cancer, cardiovascular and other diseases involving the eye & central nervous system, to explore potential targeted therapies, and look into how any products and services co-developed can be commercialised.

27/09/2024

💬 "When I try to explain to my family and friends what I do, it's always a challenge. I need to find a simple and accessible way to communicate the complexities of my work so they can truly understand it." – Valentina Tonelotto

In this video, Valentina Tonelotto shares her fascinating research journey, where she has identified a potential treatment for metastatic uveal melanoma, a rare and aggressive form of eye cancer. The compound 1,4-dihydroxy quininib has shown great promise by selectively inducing the death of uveal melanoma cancer cells in vitro. 🔬

Valentina also offers a personal glimpse into her experience at the UCD Conway Institute, University College Dublin , which attracted her for its collaborative spirit and strong connections between academia and industry. She explains how a researcher in academia must not only be a scientist but also a manager, with a 360-degree view of innovation. 🌍

🎥 Watch the video to hear her inspiring story and discover how science and teamwork are shaping the future of cancer treatment research!
👉 https://www.youtube.com/watch?v=Sl8PC5c_oJs

Thank you so much for everything! Learning how to communicate and share science better means a lot to us. Your work has ...
22/08/2024

Thank you so much for everything! Learning how to communicate and share science better means a lot to us.

Your work has made a real difference! 😊

🚀 This week marks the grand finale of our workshop series at Conway Institute! We're diving into social media & AI to he...
21/08/2024

🚀 This week marks the grand finale of our workshop series at Conway Institute! We're diving into social media & AI to help you boost your professional profiles and create impactful content 🎓. It's not too late to join—send us an email at toctoc@derotosydescosidos.com to secure your spot! 💻✨

Researchers in Prof. Breandan Kennedy's lab at the UCD Conway Institute have published a study on metastatic uveal melan...
19/08/2024

Researchers in Prof. Breandan Kennedy's lab at the UCD Conway Institute have published a study on metastatic uveal melanoma, a rare but deadly eye cancer. The research explores the potential of 1,4-dihydroxy quininib to induce cancer cell death, providing new insights into treatment possibilities.

Read more here: https://goo.su/4AUZU

How to tell your story? 🤔💭Today, with Silvia Fernández of Derotosydescosidos company, we´ve been working on how to adapt...
15/08/2024

How to tell your story? 🤔💭

Today, with Silvia Fernández of Derotosydescosidos company, we´ve been working on how to adapt a science message depending on the audience you´re going to talk with.

We put some examples and divided the class into three groups. Everyone had done a really good job! Thanks a million to all the people involved! 👏🏼

See you next week! 😜

10/07/2024

Arrancamos nuestra colaboración con en el , verano irlandés!

On this  , let's remember that individually rare diseases collectively affect millions. In fact, if all rare diseases ar...
28/02/2023

On this , let's remember that individually rare diseases collectively affect millions. In fact, if all rare diseases are added up, they become very common. Research is crucial to improve patient outcomes.
👨‍🔬👩‍🔬🔬🧪💊
We borrow this hilarious meme from for the occasion 😉

Today, on  , we stand united in the fight against this disease. CRYSTAL3 consortium works to find new and innovative the...
04/02/2023

Today, on , we stand united in the fight against this disease. CRYSTAL3 consortium works to find new and innovative therapies, committed to improve the lives of patients. Let's work together to

This is Maitiú (but you can call him Mat). He loves coffee and hates cold weather. Enjoy your secondment Mat!! 🇸🇪🐟🧫☢️👨‍🔬...
16/09/2022

This is Maitiú (but you can call him Mat). He loves coffee and hates cold weather.
Enjoy your secondment Mat!! 🇸🇪🐟🧫☢️👨‍🔬

About myself:
I am a PhD student from Dublin, Ireland. My PhD project aims to improve radiation response in oesophageal cancer (OAC) patients. My project is under the supervision of Prof. Jacintha O’Sullivan. I love coffee and friendly people – I dislike negativity and cold weather!

My role in CRYSTAL3:
My CRYSTAL3 project with Bioreperia aims to use OAC cell line-implanted zebrafish to assess CysLT receptor expression in response to radiation and treatment with novel oxygen-carrying perfluorocarbon nanoemulsions. I hope to apply the skills and knowledge I have learned during this project to my PhD project back in Dublin!


Huge Congrats to  and .nay , presenting their   work at   meeting this week. Brave fellows: optometrists from  seconded ...
09/09/2022

Huge Congrats to and .nay , presenting their work at meeting this week. Brave fellows: optometrists from seconded to in and developing new eye disease models in Research beyond multidisciplinary limits… why not??
👁️🐟🔬🧪👨🏼‍🔬👓

Exciting   Summer School (8th-11th Aug) supporting integration of displaced Ukrainian visitors and Irish-based teenagers...
02/08/2022

Exciting Summer School (8th-11th Aug) supporting integration of displaced Ukrainian visitors and Irish-based teenagers/young adults.
More info in flyers or contanting crystal3consortium@gmail.com



This is Patricia, seconded from  to  She loves travelling, dancing, flowers and tea 🛩️🩰🌻🫖About myself: I am an Optician ...
03/06/2022

This is Patricia, seconded from to
She loves travelling, dancing, flowers and tea 🛩️🩰🌻🫖


About myself:
I am an Optician expert in eye care. When I finished my master’s degree in Complutense University of Madrid, I started to work for Ocupharm Diagnostic.
I love travelling, dancing, flowers and tea. I dislike arrogant people.

My role in CRYSTAL3:
I am seconded from Ocupharm Diagnostic to International Iberian  Nanotechnology Laboratory for 3 months.
My research focuses on analysis of CysLT signally in Dry Eye Disease, Conjunctivitis and Sjögren's syndrome. Afterwards, I will evaluate ocular surface inflammatory models with CysLT simulations.
My secondment is a great opportunity to acquire new skills and laboratory experience. In addition to being able to help in future treatment of eye diseases.

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Stillorgan

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