01/12/2025
🔬 Organ-Specific Cancer Biomarkers & Their Uses
Cancer biomarkers help clinicians detect cancer early, guide treatment decisions, and monitor therapeutic response. Each biomarker is often linked to a specific organ or cancer type, making it a powerful tool in precision oncology.🧑🔬🔬
🧬 Key Organ-Specific Cancer Biomarkers
🟦 Prostate – PSA (Prostate-Specific Antigen)
• Early detection and monitoring of prostate cancer.
🟪 O***y – CA-125 (Cancer Antigen 125)
• Diagnosis, staging, and follow-up of ovarian cancer.
🟧 Liver – AFP (Alpha-Fetoprotein)
• Biomarker for hepatocellular carcinoma and germ cell tumors.
🟩 Breast – HER2/neu, BRCA1/BRCA2
• HER2 guides targeted therapy.
• BRCA mutations indicate hereditary breast & ovarian cancer risk.
🟫 Pancreas – CA 19-9
• Used in prognosis and monitoring of pancreatic cancer.
⬛ Colon/Rectum – CEA (Carcinoembryonic Antigen), KRAS Mutation
• CEA helps track colorectal cancer recurrence.
• KRAS mutation guides therapy selection.
⬜ Lung – EGFR Mutation, ALK Rearrangement
• Crucial for planning targeted therapies in lung cancer.
🟨 Thyroid – Thyroglobulin, Calcitonin
• Thyroglobulin monitors papillary & follicular thyroid cancers.
• Calcitonin is elevated in medullary thyroid carcinoma.
🎯 Why They Matter
Enable organ-specific early detection
Support precision and personalized treatment
Track therapy response and disease recurrence
Improve overall survival outcomes✨🧬
