08/03/2026
Many people believe knee arthritis pain comes from cartilage damage.
But cartilage has no nerves.
The pain often comes from subchondral bone edema — inflammation inside the bone beneath cartilage.
In this video, I explain:
• What bone marrow edema means on MRI
• Why it causes pain
• What biologic treatments attempt to address it
Watch here:
Why does your knee pain get worse the moment you lie down? If you’ve been told your cartilage is the problem, you might be looking in the wrong place. In thi...