RAJ Homoeo Clinic

18/10/2025

16/10/2025

08/10/2025

06/10/2025

🧠 Long COVID brain fog finally has a scientific explanation

For years, millions of people suffering from Long COVID have reported “brain fog”—trouble with memory, focus, and thinking clearly. Now, researchers in Japan have identified a biological cause behind these cognitive struggles.

A team at Yokohama City University used an advanced brain imaging technique called [11C]K-2 PET scanning to reveal abnormal increases in AMPA receptors (AMPARs)—molecules crucial for learning and memory—in patients with Long COVID. Elevated AMPAR levels were directly linked to both the severity of brain fog and higher inflammation markers, providing the first clear molecular evidence of the condition.

Published in Brain Communications (Oct 2025), the study found that AMPAR density could distinguish affected individuals from healthy ones with remarkable accuracy—100% sensitivity and 91% specificity. This breakthrough opens the door to new diagnostic tools and potential treatments, such as drugs targeting AMPAR activity.

With brain fog affecting over 80% of Long COVID patients worldwide, this discovery is a vital step toward validating patients’ experiences and accelerating the search for effective therapies.

📖 Reference: Yu Fujimoto et al., Systemic increase of AMPA receptors associated with cognitive impairment of long COVID, Brain Communications, 1 October 2025.

27/09/2025

26/09/2025

🧠 Chronic insomnia doesn’t just leave you tired—it can literally speed up brain aging and raise dementia risk by 40%.

A major study published in Neurology tracked nearly 2,800 older adults for over 5 years and found that chronic insomnia is far from harmless. Compared to good sleepers, those with persistent insomnia were 40% more likely to develop mild cognitive impairment or dementia.

Brain scans revealed a direct link between poor sleep and biological markers of neurodegeneration, such as amyloid plaque buildup (a hallmark of Alzheimer’s) and white matter damage linked to vascular disease. The effect of insomnia on brain health was so significant, it was equivalent to adding 3.5 extra years of aging or living with two major heart-related conditions.

The takeaway is clear: insomnia isn’t just a symptom of aging—it’s a modifiable risk factor. Addressing it through proper diagnosis and evidence-based treatments, such as Cognitive Behavioral Therapy for Insomnia (CBT-I), could be one of the most powerful ways to protect long-term brain health.

With sleep shaping everything from memory to brain structure, prioritizing rest may be as important as diet and exercise in preventing dementia.

📖 Source: Carvalho, D.Z., et al. (2025). Neurology, American Academy of Neurology.

26/03/2025

In this study, the biological functions of D. rotundifolia were explored in vitro following the treatment of bronchial epithelial cells, which are the potential targets of the pharmacological effects.

This study shows that Drosera can induce a change in mRNA expression that can be measured reliably and reproducibly. Low doses and homeopathic dilutions are now being investigated by means of molecular biology techniques for differential gene expression analysis and bioinformatics.

Screening in bronchial cells with RNA-seq analysis showed that low amounts of D. rotundifolia at a 3× dilution, which represents a dose commonly used in homeopathic and phytotherapeutic syrups, changed the expression of dozens of genes after 3 h, and this effect was amplified after 6 h of treatment. Validation with RT-qPCR confirmed the differential expression of the genes of interest and showed that after 6 h of D. rotundifolia 3× treatment, there was an increase in mRNA expression. Since RT-qPCR sensitivity is higher than that of RNA-seq, such results support the findings of the RNA-seq analysis, suggesting that treatment with D. rotundifolia × can be followed-up by the investigation of the expression of these genes.

In our experiments, D. rotundifolia 3× did not impair cell viability or adherence, suggesting that this dilution is safe when tested directly in cell culture. The same dilution exerted a stimulatory effect on the expression of several genes, . D. rotundifolia 3× works mainly as a stimulant and not as an inhibitor of cell functions.

https://go.nature.com/3rmsN2t

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23/03/2025

🌿 Celebrating Women's History Month with Dr. Margery Blackie (1898–1981) – A leading British homeopath, educator, and author, she helped keep homeopathy recognized at the highest levels of healthcare.
Trained in conventional medicine, she specialized in classical homeopathy and excelled in constitutional prescribing. In 1969, she became Physician to Queen Elizabeth II, reinforcing the royal family's long-standing support for homeopathy.
A passionate teacher and advocate, she worked to integrate homeopathy into mainstream medicine and preserve its place in the NHS. Her book "The Patient, Not the Cure" remains a homeopathic classic.