DVS BioLife Ltd

08/11/2025

Gut microbes help keep immune cells anchored in the intestine

Targeting the microbiota could be a new way to strengthen gut immunity and develop treatments for inflammatory bowel diseases such as Crohn’s disease.

02/11/2025

Enhancing Aquaculture Performance with Amino Acid–Rich Corynebacterium glutamicum Probiotic
Dear Sir/Madam,
We are delighted to present our multilayer encapsulated Corynebacterium glutamicum—a scientifically validated probiotic feed additive and water amendment agent. Its exceptional amino acid production ability leads to improved animal growth, higher body-weight gain, and enhanced weight density, making it ideal for hatcheries, grow-out ponds, and feed-mixing facilities.
________________________________________
Key Science-Based Benefits
1. Amino Acid Biosynthesis at Scale
• C. glutamicum is a globally recognized industrial microbe, responsible for million-ton scale production of amino acids such as glutamate and lysine.
• Metabolic engineering allows it to convert low-cost sidestreams—including agricultural and aquaculture by-products—into bioavailable amino acids, optimizing feed nutritional quality.
2. Higher Weight Density & Daily Gain in Aquatic Species
• In juvenile largemouth bass (Micropterus salmoides), dietary supplementation with L-glutamic acid significantly improved body muscle mass, villus structure, enzyme activity, and daily weight gain.
o A 0.6% glutamic acid-enriched diet led to larger muscle fiber area, increased total amino acid levels, and heightened expression of growth-regulated genes—ultimately enhancing growth metrics and feed efficiency.
• This clearly demonstrates the positive impact of amino acid enrichment on growth performance and protein deposition in aquatic animals.
________________________________________
Use Recommendations
Application Area Recommended Use
Feed Mixing Plants Include encapsulated C. glutamicum 10 B CFU/g at 0.25% by weight in feed formulations to enrich with amino acids like glutamate, lysine, and BCAAs.
Grow-Out Ponds Supplement water or feed to support gut health and facilitate nutrient uptake—@ 2 to 3 g of 6 B CFU/g of the microbe /Kg Feed once in a week, across production cycles.
Hatcheries Administer via rearing water at —@ 10 g of 10 B CFU/g of the microbe /KL of water to support larval development and weight gain through enhanced protein provision.
________________________________________
Mechanism:
It produces amino acids in L. form like L-glutamate, L-lysine, threonine, and isoleucine
It produces Vitamins like Biotin, pantothenate etc.
It produces Astaxanthin
It produces Organic acids like succinic acid, mycolic acid, muconic acids
It also produces lignolytic enzymes.
Advantages Summary
• Enhanced Weight Density & Growth: Amino acid–enriched diets improve muscle fiber development and daily weight gain.
• Superior Nutrient Utilization: Boosted digestive enzyme activity (protease, amylase, lipase) supports better feed efficiency.
• Optimized Feed Conversion Ratios: Higher bioavailability of critical amino acids accelerates biomass accumulation.
• Sustainable & Economical: Leverages low-cost sidestreams to produce high-value amino acids for aquaculture feed.
________________________________________
Scientific References
1. Frontiers in Microbiology (2022): Illustrates C. glutamicum's capacity for large-scale amino acid production from agri and aqua-streams.( Frontiers | Metabolic Engineering for Valorization of Agri- and Aqua-Culture Sidestreams for Production of Nitrogenous Compounds by Corynebacterium glutamicum)
2. MDPI Fishes (2024): Documents improved growth performance, muscle development, amino acid content, and daily gain in largemouth bass following glutamic acid supplementation. [ Effects of Dietary L-glutamic acid on the Growth Performance, Gene Expression Associated with Muscle Growth-Related Gene Expression, and Intestinal Health of Juvenile Largemouth Bass (Micropterus salmoides)]
3. Amino Acid Production by Corynebacterium glutamicum (Amino Acid Production by Corynebacterium glutamicum | SpringerLink)
4. From Aquaculture to Aquaculture: Production of the Fish Feed Additive Astaxanthin by Corynebacterium glutamicum Using Aquaculture Sidestream (From Aquaculture to Aquaculture: Production of the Fish Feed Additive Astaxanthin by Corynebacterium glutamicum Using Aquaculture Sidestream - PMC)

5. Corynebacterium glutamicum - an overview | ScienceDirect Topics

25/10/2025

The best prebiotics for increasing butyrate—a short-chain fatty acid crucial for gut health, anti-inflammation, and metabolic balance—are specific fibers and polyphenols that selectively feed butyrate-producing bacteria such as Faecalibacterium prausnitzii, Roseburia spp., and Eubacterium rectale.​
Top Prebiotics That Generate Butyrate


Prebiotic Type
Primary Substrate
Key Butyrate-Producing Bacteria Stimulated
Supporting Evidence
Inulin and Fructooligosaccharides (FOS)
D-Fructose
Faecalibacterium prausnitzii, Roseburia, Eubacterium rectale, Anaerostipes
Potent in humans and animal models ​
Resistant Starch (RS2 & RS3)
Retrograded amylose
Roseburia intestinalis, Eubacterium rectale
Strongest natural substrate for butyrate synthesis ​
Galacto-oligosaccharides (GOS)
Galactose
Anaerostipes caccae
Excellent for colonic fermentation and mild digestion ​
Arabinoxylan / Xylan
D-Xylose
Roseburia/Eubacterium group
Common in whole grains and fiber supplements ​
Guar Gum (Partially Hydrolyzed)
Galactomannan
Roseburia, Butyricicoccus, Anaerobutyricum
Enhances total butyrate pool in colonic models ​
Pectin (from fruits)
Galacturonic acid
Eubacterium eligens, Faecalibacterium
Milder prebiotic, synergistic with polyphenols ​
Polyphenolic Prebiotics (catechins, anthocyanins, proanthocyanidins)
Plant phenolics
Faecalibacterium, Butyricicoccus, Anaerobutyricum hallii
Stimulate butyrate via non-fiber route ​
Most Effective Combinations (Synbiotics)
Combining prebiotic fibers with compatible probiotics enhances butyrate output (called synbiotics).
Best combinations include:
Inulin + Faecalibacterium prausnitzii or Bacillus subtilis DSM 32315​
Resistant starch + Lactobacillus plantarum (cross-feeding acetate → butyrate)​
Practical Guide
For human application:
Begin with 5–10 g/day of inulin or resistant starch, increasing gradually.
Combine with polyphenol-rich foods like berries, green tea, or cocoa for synergistic effect.
Avoid prolonged low-fiber or high-protein diets, which sharply decrease butyrate producers.​
In summary, inulin, resistant starch, and polyphenolic prebiotics are the most potent for increasing butyrate levels in the colon, especially when part of a synbiotic regime involving Faecalibacterium and Roseburia species.

25/10/2025

Dear Nutraceutical industry Colleague,

The Nutraceutical industry is increasingly focusing on the development of functional dietary supplements that offer health benefits beyond basic nutrition. DVS Biolife Ltd is a company that has made strides in this area, particularly with their range of functional dietary supplements. These supplements are designed to provide consumers with the benefits of traditional medicinal plants in a modern and convenient form.

DVS Biolife’s products are strengthened with synergic adjuvants like Nano Minerals, Enzymes, and Essential Oils, which enhance the efficacy of the natural compounds found in plants such as Saponins, Curcumin, and Carvacrol1. These compounds are known for their medicinal properties and are becoming more difficult to source in their natural form. By breaking down these plants to their essence, DVS Biolife allows consumers to easily incorporate the benefits of these traditional remedies into their daily regimen.

The company’s commitment to non-GMO products and the use of microorganisms for solving complex problems in various fields, including human and animal health, food processing, and environmental protection, positions them as a forward-thinking player in the Nutraceutical industry1.

As the industry continues to grow, companies like DVS Biolife are essential in bridging the gap between traditional medicine and modern dietary needs, providing innovative solutions for health and wellness.

The following documents will help in understanding us and our products relating Nutraceuticals and Functional Dietary Supplements.
Brochure 2022.docx
Controlling Gluten Allergy.docx
ONCOSUPP Microbial.docx
BALL GLADDER CANCER TREATMENT.docx
CML CARE.docx
WOMEN WELLNESS - Copy.docx
Carcinoma Nano Particles of Gold as Cancer Care Alternative Adjuvant to reduce intensity and frequency of Chemotherapy and Radiation .docx
BioCareSkin.docx
IMMUGOLD Prsentation to Health Professionals.docx
LACTOMA.docx
LOVECARE.docx
CUNAPI NanoCurcumin.docx
OREPHYTOBIOTIC.docx
Longevity Antiaging.docx
LACTOGEN.docx
CoRinse.docx
NanoFe.docx
PREVENTING ORAL CANCER.docx Brochure 2022.docx
CALSORB TONIC_HUMAN.docx
Cordyceps militaris for use in Humans.docx
TREHALOSE with L Planatarum to protect smoke related diseases.docx
HemaShila.docx
Role of Lactobacillus reuteri in wound healing.docx
COLLOIDAL COCONUT WATER.docx
ProSport.docx
PROELD.docx

Please feel free to contact us for any further assistance.

Thanks for your time in going through this.

Best Regards
Vijay

25/10/2025

Dear Gentlemen involved in Microbiology and Nano Technology,

You may please arrange to forward this to your Purchase/R and D departments.

Unleashing the Power of Microbes and Nanotechnology:

Greetings of the day !!!!!!
We take this opportunity to introduce ourselves and we thank you for your quality time which will not be wasted.

We are the leading manufacturers of beneficial microorganisms. We have more than 200 microbes with us out of which around 30 are own IP.
We are the lone manufacturers of Nano Minerals in India employing our novel patented process.

DVS Biolife Ltd., is a leading biotechnology company specializing in the development and production of innovative microbial and nano technology products for the animal feed industry.
We are confident that our solutions can significantly benefit your feed mixing plant and offer a competitive edge in the market.

You may Please visit our website www.dvsbiolife.in

At DVS Biolife, we harness the immense potential of microbes and nanotechnology to create cutting-edge solutions that address key challenges in Nutraceutical sector.

Our product portfolio includes:
A. Probiotics: Our advanced probiotic formulations enhance gut health, boost immunity, provide nutrition and health to elderly, pregnant, Nursing mothers, Kids, Athletes, Patients suffering with Obesity, T2Diabetes, Cancer, Depression; leading to better wellness and reduced reliance on antibiotics.

Allow me to elucidate their significance:
Synbiotics: These are specific combinations of prebiotics (non-digestible food substances) and probiotics (living microbes). Synbiotics work synergistically to stabilize and support the gut microbiota. By selectively favoring the growth and metabolite production of probiotics, they contribute to metabolic health improvement. Probiotics, being safer and effective, have shown promise against various diseases. When combined with suitable prebiotic substrates, Synbiotics become powerful therapeutic agents that offer the benefits of both probiotics and prebiotics.

Gut Microbiome Dysbiosis: Imbalance in the gut microbiome can lead to the generation and progression of chronic diseases. Synbiotics play a crucial role in modulating the gut ecosystem, directly impacting the onset and development of related disorders.

Future Prospects: Synbiotics are poised to become essential functional foods in the future. Their mechanistic overview, therapeutic potential, and promising health benefits have been extensively studied and documented in the available literature.

Holistic Approach: By focusing on the ecological and functional features of the microbiota, we can harness the full potential of Synbiotics for maintaining healthy gut microbiota. This, in turn, positively influences overall health and well-being.

In light of these exciting advancements, I encourage you to explore the vast potential of novel human gut microbes.
As we delve deeper into their mechanisms of action, safety profiles, and clinical effectiveness, we pave the way for transformative therapies and functional dietary supplements.

Some of the Novel Microorganisms that are available with us.
Readily available:
Akkermansia muciniphila
Lactobacilli
Bifidobacteria
Bacillus
Saccharomyces boulardii
Clostridium butyricum
Enterococcus
Pediococcus
Paracoccus

B. Nanoscale Minerals & Nutraceuticals: Our unique nanotechnology platform allows for the delivery of essential minerals and nutraceuticals with enhanced bioavailability, ensuring optimal nutrient uptake and improved animal health.

Allow me to elucidate their significance:
Nano Gold: Immuno-modulator, Cancer diagnostic and therapeutic
Nano Silver: Intelligent Biocide
Nano Curcumin with piperine: Cancer adjuvant
Nano Ca: Osteoporosis, Arthritis
Nano Fe: Anaemia
Nano Zn, Mn, Mg, Mo, Se etc:
We are also offering FSSAI approved products.

Should you find interest in any of the products, please feel free to address us for any further assistance.

Thanks again for your quality time and with best Regards,
Vijay

Industrial fisheries and shrimp cultivation demand extreme care and supervision to ensure sustainable Performance and survival rate and equitable conversion of food to body ratio. 

25/10/2025

Subject: Partnership Opportunity: Optimizing Animal Health and Performance with DVS Biolife Ltd.
Dear Colleague in aquaculture industry,
In the ever-evolving world of animal nutrition, DVS Biolife Ltd stands at the forefront, offering cutting-edge functional feed supplements that revolutionize the health and productivity of livestock, aquaculture, and pets alike. Our innovative products harness the power of nature and science to create a harmonious balance in animal gut health, immunity, and overall well-being.

We are excited to introduce our innovative solutions and explore potential partnership opportunities to benefit your business and the aquaculture industry.
As one of the top manufacturers in India, DVS Biolife Ltd. is committed to developing and delivering cutting-edge, sustainable, and cost-effective solutions for aquaculture. Our dedication to research and development has resulted in a diverse portfolio of proprietary and patented products, including:
• Probiotics: Our diverse range of beneficial bacteria and yeasts enhance gut health, improve nutrient utilization, and strengthen immune systems, leading to higher survival rates and reduced susceptibility to diseases.
• Nano Minerals: Our unique nano-encapsulated minerals offer superior bioavailability, improving feed quality and utilization, while promoting growth and reducing environmental impact.
• Nano Alkaloids: These naturally derived compounds act as growth promoters, stress reducers, and immunomodulators, optimizing overall health and performance.
• Nano Vitamins: Highly bioavailable nano-encapsulated vitamins ensure efficient absorption and utilization, improving nutrient status and overall health.
• Phyto Derivatives: Plant-based extracts act as natural antimicrobials, immunostimulants, and growth promoters, offering a sustainable and eco-friendly approach to health management.

By incorporating DVS Biolife Ltd.'s solutions into your product range or use them as inputs in your formulations, you can offer your customers:
• Improved survival rates and growth performance in aquatic animals.
• Enhanced disease resistance and immune system function.
• Reduced use of antibiotics and chemicals, promoting sustainable and environmentally friendly aquaculture practices.
• Increased profitability for farmers through improved efficiency and reduced mortality.
SIGNATURE PRODUCTS:
· Thermotolerant Cryoprotected Nutrients like Probiotics, Enzymes and Vitamins
Nano Minerals
Fly and Insect Larvicides
Microbes to produce Amino Acids in the gut
TRENDING PRODUCTS
· Taming Urea for higher inclusion safely
Nano Immuno Modultors
Cellulose and Lignin into Single Cell Protein
Neonatal Nutrition
Nano Calcium
Nano Phosphorus
Nano Flax Seed Oil : For enhancing Daily body weight gain
Nano Siver: Intelligent Biocide
Stimuliv: Hepato protector
NANDIMIN: Cattle Mineral Mixture


We understand the specific needs and challenges faced by aquaculture supplement manufacturers. DVS Biolife Ltd. is committed to collaborating with our partners to customize solutions, provide technical support, and conduct joint research initiatives.
We are confident that our innovative products, expertise, and collaborative approach can make a significant contribution to your business and the future of sustainable aquaculture. To learn more about our specific offerings and discuss potential partnership opportunities, please do not hesitate to contact us by mail (dr.vijay@agrilife.in)
We look forward to hearing from you soon and exploring the possibilities of working together to create a healthier and more sustainable future for aquaculture.
Sincerely,
Vijay
DVS Biolife Ltd.

25/10/2025

Gluten Sensitivity Could Be More To Do With the Gut–Brain Axis Than Gluten

Discover the results of a new study suggesting that most people with non-celiac gluten sensitivity might not be reacting to gluten after all.