Metro Clinical Laboratory

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10/03/2022

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20/01/2022
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01/01/2021

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New Delhi: More accurate than a rapid antigen test and almost as quick, India's CRISPR 'Feluda' COVID-19 test that chang...
29/09/2020

New Delhi: More accurate than a rapid antigen test and almost as quick, India's CRISPR 'Feluda' COVID-19 test that changes colour on detection of the SARS-CoV-2 virus could be a cheaper, faster and simpler alternative to an RT-PCR diagnosis, say scientists.
Named after Satyajit Ray's famed detective, the Feluda test, which is priced at Rs 500 and can deliver a result in 45 minutes, is able to differentiate SARS-CoV-2 from other coronaviruses even if genetic variations between them are minute.

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Feluda test, developed by the New Delhi-based CSIR-Institute of Genomics and Integrative Biology (IGIB) and the TATA Group, received regulatory approvals last week from the Drug Controller General of India (DCGI) for commercial launch.

It meets high quality benchmarks with 96 per cent sensitivity and 98 per cent specificity for detecting the novel coronavirus, Debojyoti Chakraborty, a senior scientist at CSIR-IGIB and part of the team that developed the test, told PTI.

In any diagnosis, sensitivity is defined as the ability of a test to correctly identify individuals with the disease, whereas specificity is the ability of the assay to accurately identify those without the disease.

File image for representation: ReutersIn a recent development in the global search for a potential vaccine for Covid-19,...
26/09/2020

File image for representation: Reuters
In a recent development in the global search for a potential vaccine for Covid-19, scientists have identified highly effective antibodies against the novel coronavirus, which they say can lead to the development of a passive vaccination for Covid-19.

Researchers said that unlike in active vaccination, passive vaccination involves the administration of ready-made antibodies, which are degraded after some time. However, the effect of a passive vaccination is almost immediate, whereas with an active vaccination it has to build up first.

The research, published in the journal Cell, also shows that some SARS-CoV-2 antibodies bind to tissue samples from various organs, which could potentially trigger undesired side effects.

The scientists at the German Center for Neurodegenerative Diseases (DZNE) and Charite - Universitatsmedizin Berlin isolated almost 600 different antibodies from the blood of individuals who had overcome Covid-19, the disease triggered by SARS-CoV-2.

By means of laboratory tests, they were able to narrow this number down to a few antibodies that were particularly effective at binding to the virus.

The researchers then produced these antibodies artificially using cell cultures.

The so-called neutralising antibodies bind to the virus, as crystallographic analysis reveals, and thus prevent the pathogen from entering cells and reproducing, they said.

In addition, virus recognition by antibodies helps immune cells to eliminate the pathogen. Studies in hamsters -- which, like humans, are susceptible to infection by SARS-CoV-2 -- confirmed the high efficacy of the selected antibodies.

"If the antibodies were given after an infection, the hamsters developed mild disease symptoms at most. If the antibodies were applied preventively -- before infection -- the animals did not get sick," new agency PTI quoted coordinator of the research project, Jakob Kreye, as saying.

26/08/2020

Urgent required B+ve Plasma Donar .

 #ప్లాస్మా అంటే ఏమిటి..రక్తం కావాలంటే వెంటనే వచ్చి ఇస్తున్నారు,ప్లాస్మా అనగానే బయపడుతున్నారు...మన రక్తంలో నీటి మాదిరిగా ...
11/08/2020

#ప్లాస్మా అంటే ఏమిటి..
రక్తం కావాలంటే వెంటనే వచ్చి ఇస్తున్నారు,ప్లాస్మా అనగానే బయపడుతున్నారు...
మన రక్తంలో నీటి మాదిరిగా ఉండే #పసుపుపచ్చని ఫ్లూయిడ్ నే ప్లాస్మా అంటారు...
కరోనా వంటి వైరస్ లు మన శరీరంలోకి చేరినప్పుడు వాటిని #తెల్లరక్త కణాలు గుర్తించి, చంపేందుకు కావలిసిన యాంటీబాడీలు తయారవుతుంటాయి...
ఆ యాంటీ బాడీలు ప్లాస్మాలోనే ఉంటాయి....
కరోనా నుంచి కోలుకున్న పేషెంట్ల ప్లాస్మా లోనూ ఈ యాంటీ బాడీలు పెద్దసంఖ్యలో తయారై ఉంటాయి..
అందువల్ల సీరియస్ కండిషన్ లో ఉన్న పేషెంట్లకు, ఆల్రెడీ వైరస్ సోకి కోలుకున్న పేషెంట్ల ప్లాస్మాను ఎక్కిస్తే...త్వరగా కోలుకుని,ప్రాణాపాయం నుండి బయటపడే చాన్స్ ఉంటుంది...
(ఇప్పుడున్న పరిస్థితుల్లో ఈ ఇన్ఫర్మేషన్ చాలా అవసరం plz వీలైనంత ఎక్కువ మందికి తెలియజేయండి)

Plasma therophy for covid patients..
11/08/2020

Plasma therophy for covid patients..

Give blood .....Save life..
14/06/2020

Give blood .....Save life..

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