01/11/2025
Publication Alert !!!
Honoured to collaborate as the core group member for PRECEDENT Study Group which now has published the findings as "A core outcome set for locoregional treatment reporting in neoadjuvant systemic breast cancer treatment trials" in npj Breast Cancer. As part of the Springer Nature SharedIt initiative, a stable, shortened URL is now available to share full-text access by using the following link:
https://rdcu.be/eM8c3
Accurate information about locoregional breast cancer treatments following neoadjuvant systemic therapy (NST) is essential for meaningful interpretation of oncological outcomes but reporting is currently poor. We developed a core outcome set (COS) to improve the quality and consistency of locoregional outcome reporting in breast cancer NST trials. The COS was developed in three phases according to COS-STAD guidance, with the generation of a list of relevant outcome domains, prioritisation of outcomes through two rounds of an international online multi-stakeholder Delphi survey and a consensus meeting. 159 unique locoregional outcomes were classified into 101 outcome domains for inclusion in the Delphi survey, which was completed by 470 international professionals. Widespread COS implementation will improve the quality and value of future NST trials.