29/03/2026
Today, Dr. Abhishek Shukla explained the physiological changes that lead to weakening of bones with advancing age. He described this process as part of degenerative changes, where there is a gradual decline in bone mineral density (BMD). As bone mass decreases, the structural integrity of bones weakens, making them more prone to fractures and functional limitations.
He outlined the progression of bone health deterioration, beginning with osteopenia, a stage of reduced bone density that precedes more severe conditions. If not addressed, this can progress to osteoporosis, where bones become significantly fragile. Over time, degenerative joint involvement may lead to osteoarthritis, characterized by pain, stiffness, and reduced mobility, and in advanced stages, this may result in deformities affecting posture and overall quality of life.
Dr. Shukla also discussed the role of bone-forming and anti resorptive agents in management. Medications such as teriparatide (a bone forming agent) and denosumab (which reduces bone resorption) are used in appropriate cases to improve bone strength and reduce fracture risk. He emphasized that early identification, along with medical management and lifestyle modifications, is essential to prevent progression and maintain skeletal health.