27/11/2025
The Problem is Insulin Resistance
Since we are in the final week of world diabetes month, it is relevant to talk about the condition a lay person understands.
Insulin is the hormone that helps glucose enter your cell. Insulin resistance is a condition where the body's cells don't respond normally to the hormone insulin, leading to higher blood glucose levels and potentially prediabetes or type 2 diabetes. It is often caused by excess body fat, especially around the abdomen, and an inactive lifestyle, but can also be linked to genetics and certain medical conditions. Symptoms are often not present, and the condition is frequently diagnosed during routine medical tests, but signs like dark skin patches (acanthosis nigricans) or high blood pressure can occur. Lifestyle changes like a healthier diet anregular exercise are the most effective ways to improve insulin sensitivity and manage the condition. What it is A condition where your body's cells stop responding to insulin, a hormone that helps glucose (sugar) from your food get into your cells for energy. This makes it harder for glucose to enter the cells, causing it to build up in the bloodstream. This can lead to high blood sugar levels and, if the pancreas can't keep up, the development of prediabetes and eventually type 2 diabetes. Causes and risk factors Excess body fat: Particularly around the abdomen (belly fat), which can interfere with insulin's function. Physical inactivity: A sedentary lifestyle contributes to insulin resistance. Diet: A diet high in processed foods and sugary drinks is linked to the condition. Genetics: Family history increases your risk. Other factors: This includes certain medications, sleep apnea, and hormonal disorders like PCOS. Symptoms Often, there are no noticeable symptoms, and it's detected through blood tests. Acanthosis nigricans: A thickening and darkening of the skin, often in the armpits, groin, and neck. High blood pressure: Readings of \(130/80\) or higher. High triglyceride levels and low HDL cholesterol: May be detected in blood tests. Management and prevention Weight loss: Losing even a small amount of weight, especially from around the liver, can significantly improve insulin resistance. Exercise: Regular physical activity, like walking or taking the stairs, can help your body become more sensitive to insulin. Healthy diet: Eating a balanced diet rich in fruits, vegetables, and lean protein, and limiting sugary drinks and processed foods. Manage associated conditions: Working with a healthcare provider to manage conditions like PCOS or fatty liver can also help.