08/12/2025
Agilent InfinityLab Poroshell 120 columns
InfinityLab Poroshell 120 columns are based on superficially porous particle technology, which features a solid silica core and a porous outer layer. Compared to traditional totally porous particles of the same (or similar) size, Poroshell particles deliver higher chromatographic efficiencies and enable fast, highresolution separations. Poroshell superficially porous particles offer several advantages over totally porous particles:
– Uniform particles with smooth surfaces, ensuring smaller particle size distributions
– Short analyte diffusion path in/out of the porous layer
– Narrow particle size distributions, allowing more uniform packing of column particles
InfinityLab Poroshell 120 superficially porous columns for reversed-phase liquid chromatography (LC) separations offer exceptional efficiency and reliability across a broad range of applications. With chemistries that span general-purpose, basic, acidic, polar, and chiral compounds, the family makes it easy to choose the right column for your method: EC-C18 is the starting point for routine methods, HPH-C18/HPH-C8 support high-pH basic analytes, SB-C18/SB-C8 are optimized for low-pH acidic compounds, Aq-C18 and HILIC phases boost retention of polar analytes, and dedicated chiral phases enable rapid enantiomer separations.
Twenty chemistries - from various C18 options to unique phenyl, CN, HILIC, and chiral chemistries - are available in up to three particle diameters: 1.9 μm, 2.7 μm, and 4 μm, giving you scalable selectivity from traditional high-performance liquid chromatography (HPLC) to ultralow dispersion UHPLC.
Features
Superficially porous, �core-shell� particles that provide both improved throughput and higher resolution
A scalable particles - including 1.9 μm, 2.7 μm, and 4 μm to match your methods, instruments, and method requirements from HPLC to UHPLC
Superior peak shapes from high-purity silica and advanced bonding chemistries for accurate quantitation
Easy method development with the selectivity from 13 reversed phase chemistries
Excellent lot-to-lot reproducibility giving you confidence in your separation results
Part of the InfinityLab ecosystem for maximum compatibility with Agilent instruments, supplies, and workflows