LCGC Bioanalytic Solutions, 105, Champaklal Indl Estate, Nr. Sion tele. exchange, Sion-(E) Mumbai, Sion (2025)

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105, Champaklal Indl Estate, Nr. Sion Tele. Exchange, Sion-(E) Mumbai

10/10/2025

GL Science InertSustain Cyano.

The Most Reliable and Reproducible Cyano Column

In general, the stability and reproducibility of the Cyano phase available in the market are poor. Many batch-to-batch or lot-to-lot reproducibility issues are occurring at many laboratories. The InertSustain Cyano columns were developed to resolve these problems and are designed using the most modern LC column technology available providing them to be extremely inert, stable and reproducible. The InertSustain Cyano columns are highly recommended for all pharmacopeia methods requiring a Cyano phase to be used. (Ex: USP L10)

Benefits

■ Endlessly reproducible from column-to-column and batch-to-batch

■ Highly recommended for all pharmacopeia methods requiring a Cyano phase to be used (Ex: USP L10)

■ Highly inert packing material results in less tailing of peaks for virtually any type of analytes

■ A new selectivity option for method development due to the multiple retention mechanisms

■ Originally shipped in reversed-phase solvents and is ready to use for reversed-phase methods

■ Can be used for both reversed-phase separations as well as normal-phase separations

Base Material : High Purity ES Silica GelParticle Size : 3 µm, 5 µm

Surface Area : 350 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 0.85 mL/g

Functional Group : Cyanopropyl

End-capping : Yes

Carbon Loading : 8.0 %

pH Range : 2 - 7.5

03/10/2025

GL Sciences Inertsil Hybrid-C18.

High-pH Tolerant HPLC Column for Robust and Reproducible Performance

Introduction & Key Features

Inertsil Hybrid-C18is a silica-basedreversed-phase column engineered with hybrid organic-inorganic

bonding technology, enabling exceptional chemical stability across a broad pH range of 1–12.

● pH range 1–12 for both acidic and basic conditions

● Excellent batch-to-batch reproducibility

● Compatible with LC/MS, LC/MS/MS and high-pressure LC systems

● High durability and long lifetime, even under basic pH

● USP L1 classification (C18)

Specification

Base Material : High-pH Stable Hybrid Silica

Particle Size : 1.7 µm / 3.5 µm / 5 µm

Pore Size : 165 Å (16.5 nm)

Pore Volume : 1.00 mL/g

Surface Area : 185 m²/g

Carbon Load : 15%

End-capped : Yes

USP Code : L1

Max Temp : 80°C (pH 1 - 10), 60°C (pH 1 - 12)

pH Range : 1 – 12

Max Pressure 1.7 µm: 18,000 psi (124 MPa) — PEEK hardware: 14,500 psi (100 MPa) 3.5 µm: 7,200 psi (50 MPa) 5 µm: 6,000 p

A Legacy of Quality

Since the launch of Inertsil ODS-3 in 1994, we have consistently manufactured HPLC columns in-house—from the synthesis of base silica to final packing. This fully integrated production process is the foundation of our ability to deliver high-quality, highly reliable columns with unmatched consistency

Inertsil Hybrid-C18 was newly developed to meet the evolving needs of users, offering exceptional durability under high-pH mobile phase conditions. This column expands application flexibility while maintaining the trusted performance of the Inertsil series.

25/09/2025

HPLC, LC/MS Columns

InertCore Core-Shell HPLC Column

High-Performance Core-Shell Columns for UHPLC and HPLC

Core-Shell Technology for Enhanced Column Efficiency

In core-shell particles, analyte molecules pass through a thin porous shell surrounding a solid non-porous core. This structure significantly reduces diffusion within the particle compared to fully porous particles, resulting in sharper peaks and higher theoretical plate numbers

Advantages of Core-Shell Packing Material

●Excellent particle size distribution minimizes multiple-path diffusion, enhancing efficiency and peak sharpness.

●A 2.6 μm core-shell particle delivers a comparable number of theoretical plates to that of a sub-2 μm fully porous particle, but with the backpressure of a 3 μm fully porous column.

●The number of theoretical plates is increased by minimizing diffusion within the particle.

17/09/2025

GL Sciences InertSphere Sugar-1.

InertSphere Sugar-1 is a suitable anion-exchange column for sugar analysis. It is packed quaternary ammonium group binding polymer. High sensitivity sugar analysis is available using an electrochemical detector. Especially InertSphere Sugar-1 is suitable for Monosaccharide and Disaccharide analysis.

Note) Solvent Bottle with CO2 Trap Cartridge is necessary for analysis to avoid dissolving carbonate ion in the solvent. The Solvent Bottle CO2 Trap Cartridge contains hazardous material which requires special freight handling. Additional charges apply.

Specification :

Base Material : Styrene Divinylbenzene copolymerization

Particle Size : 5 µm

Ion Exchange Capacity : 0.7 meq/g

Functional Group : Quaternary Alkylamine

pH Range : 2 - 14

Maximum Operating Pressure : 15 MPa (150 bar)

Organic solvent resist : 0 % - 100 % (Methanol only)

04/09/2025

GL Sciences InertSustain Amide .

InertSustain Amide is a HILIC column that enhances the retention of extremely polar compounds.

This column offers the strongest retentivity among the marketed amide columns through bonding of carbamoyl groups. It achieves superior stability and durability even for water-rich mobile phases.

HILIC phases are particularly useful for compounds that are weakly retained by reversed phase columns such as Melamine and Cyanuric Acid.

As shown below, InertSustain Amide provides stronger retention for such analytes compared to other HILIC brand columns.

Specification.

Base Material : High Purity ES Silica Gel

Particle Size : 3 µm, 5 µm

Surface Area : 350 m2/g

Pore Size : 100 Å (10 nm）

Pore Volume : 0.85 mL/g

Functional Group : Carbamoyl

End-capping : None

Carbon Loading : 15.0 %

USP Code : L68

pH Range : 2 - 8.5

20/08/2025

GL Sciences InertSustain Phenylhexyl

InertSustain Phenylhexyl columns are bonded with phenylhexyl groups, which employs a phenyl ring with a hexyl (6- carbon) linker and is densely bonded to our newly developed ES silica gel delivering complementary selectivity to straight alkyl-chain columns, but with industry leading inertness, lot-to-lot reproducibility and low back pressure.

Base Material : High Purity ES Silica Gel

Particle Size : 3 µm, 5 µm

Surface Area : 350 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 0.85 mL/g

Functional Group : Phenylhexyl

End-capping : Yes

Carbon Loading : 9.0 %

USP Code : L11

pH Range : 1 - 10

12/08/2025

GL Sciences InertSustain AX-C18.
InertSustain AX-C18 is a mix-mode column, where C18 groups and tertiary amino groups are chemically bonded to silica gel. It provides hydrophobic interaction and the electrostatic interaction by AX group works. By controlling the amount of AX group, acidic compounds can be eluted even in buffer concentration range used with LC/MS. It performs an excellent reproducibility and stable quality.

Base Material：High Purity ES Silica Gel
Particle Size：1.9µm、3µm、5µm
Surface Area：200m2／g
Pore Size：200Å
Pore Volume：1.00mL／g
Functional Group：Octadecyl＋Alkylamino (tertiary amine)
End-capping：Yes
Carbon Loading：8.0%
pH Range：1～9

09/08/2025

Happy Raksha Bandhan.

There is satisfaction in weaving protecting threads, which represent love and lifetime connection, much as sisters tie rakhis together to represent love and unification.

01/08/2025

GL Sciences Inertsil C8-3.

The same base silica gel and bonding technology that is used for Inertsil ODS-3 is also employed for Inertsil C8-3. The difference between the two phases is just the length of the hydrocarbon ligands. 10 μm particle size columns are also available to meet the requirement of various pharmacopeia methods. We recommend InertSustain C8 columns for all new method development.

Base Material: 3 Series High Purity Silica Gel

Particle Size: 2 µm, 3 µm, 5 µm, 10 µm

Surface Area: 450 m2/g

Pore Size: 100 Å (10 nm)

Pore Volume: 1.05 mL/g

Functional Group: Octyl

End-capping: Yes

Carbon Loading: 9.0 %

USP Code: L7

pH Range: 2 - 7.5

17/07/2025

GL Sciences Inertsil ODS-HL.

Inertsil ODS-HL employs a highly inert packing material which provides pure hydrophobic interaction between analytes without generating any secondary interaction delivering sharp peaks. High-Density bonding of C18 phase delivers alternative selectivity to conventional C18 columns. Inertsil ODS-HL column is applicable for impurities in pharmaceuticals analyisis.

Base Material : 3 Series High Purity Silica Gel

Pore Size : 1.9 µm, 3 µm, 5 µm, 10 µm

Surface Area : 450 m2/g

Pore Size : 100 Å (10 nm)

Pore Volume : 1.05 mL/g

Functional Group : Octadecyl

End-capping : Yes

Carbon Loading : 23.0 %

USP Code : L1

pH Range : 2 - 7.5

14/07/2025

GL Sciences InertSphere Sugar-1.

InertSphere Sugar-1 is a suitable anion-exchange column for sugar analysis. It is packed quaternary ammonium group binding polymer. High sensitivity sugar analysis is available using an electrochemical detector. Especially InertSphere Sugar-1 is suitable for Monosaccharide and Disaccharide analysis.

Note) Solvent Bottle with CO2 Trap Cartridge is necessary for analysis to avoid dissolving carbonate ion in the solvent. The Solvent Bottle CO2 Trap Cartridge contains hazardous material which requires special freight handling. Additional charges apply.

LCGC Bioanalytic Solutions

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