29/07/2020
*CME INDIA HIGHLIGHT*
29TH July
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Key points from the discussion from *Paradigm Shift* from March to July 20 Webinar
(Faculty:
Dr K K Agarwal
Dr RV Asokan
Dr Ramesh K Datta,
Dr Jayakrishnan Alapet
Dr Brijendra Prakash
Dr Sanchita Sharma)
тнХCovid-19 was first considered to be a viral pneumonia, but now it is known as a mysterious virus, which is predictable unpredictable.
тнХIt spares joints and larynx, so no joint involvement or hoarseness of voice; also, no lymph nodes involvement.
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*Covid-19 was earlier believed to be non-inflammatory, but we now know that it is predominantly an inflammatory disease*.
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*Earlier, it was thought that the patient could become critical on any day of the illness; now we know that Days 3-6 are the days to watch*.
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*Social distancing has changed to physical distancing*.
тнХFrom macrodroplets (surface to human transmission) earlier, we now talk of microdroplets (crowded ill ventilated rooms) today.
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*Surface to human transmission was the most important route of transmission'now it has become less* important (heat and humidity)
тнХThe shift from no masking to mandatory masking in public has become the norm.
тнХFrom simple masks, we have moved to N95 masks for all high risk patients (COPD, asthmatics)
тнХMasking only when going out, now adds *masking also at home*.
тнХDistancing of 3 feet has changed to 6 feet; with microdroplets, this distance is now 9 feet.
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*We started the pandemic with very high mortality (10%)*; *now mortality is around 0.3%*.
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*Institutional care has shifted to home care*
тнХIn the early days, no treatments were available; but individualized treatment is now available. If inflammatory parameters are raised, then give steroids, if d-dimers are high, give anticoagulant, if early presentation, give antiviral etc.
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*From mandatory ventilation, the concept has changed to noninvasive ventilation*.
тнХChildren to grandparents; now children are no risk for transmission to adults or other children.
тнХMenstruation reduces severity of illness.
тнХWe have shifted to no steroids to early low dose steroids.
тнХHydroxychloroquine (HCQ) for all to no HCQ for mild cases.
тнХLate discharge тАУ earlier patients were kept for 30-40 days; now patients are discharged early (Day 6) if no complications, to home quarantine
тнХThinking of death to thinking recovery
тнХNo pooled test to pooled test
тнХWe have now understood that after 9 days of illness, the virus is non-culturable and the person is non-infectious, the presentation is post-Covid sequelae due to persistent inflammation, or hypercoagulable state. Before 9 days, it is covid.
тнХNo Ct value to Ct value of RTPCR to find out if cohort isolation can be done; low Ct value means high viral load.
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*Testing has moved from antigen RTPCR to rapid antigen and now antibodies testing (total vs IgG)*
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*Isolation to cohort isolation (multiple infected persons in a family can stay together)*
тнХIsolation and now isolation/quarantine/monitoring
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*From no oxygen at home to oxygen at home*
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*Closed camps/OPDs to open sunlight camps тАУ microdroplets are killed in sunlight*
тнХEarlier testing was done only for symptomatic persons, but now liberal testing
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*A mandatory government prescription has now become non-mandatory*
тнХWhen it first began in Wuhan, China, it was pulmonary COVID and CT diagnosis was a must; but now it is also recognized as non-pulmonary COVID, involving GIT, CNS.
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*Typically, fever at the time of presentation; now no fever presentation*
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*Asymptomatic persons are really not asymptomatic; they may have some atypical symptoms such as diarrhea, sore throat etc*.
тнХHigh grade fever, which is classically associated with viral illness to low grade (100oF) exertional persistent fever, due to persistent inflammatory process
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*The six minute walk test (6MWT) was meant for only COPD, heart failure patients, but it is now mandatory from Day 3-6*. If the patient desaturates by *5%* on walking, this is indicative of pneumonia with thrombosis. This is an emergency.
тнХTransmission from joint families to nuclear families
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*No toilet transmission*, *now toilets are recognized as a covid chamber*
тнХContact time from 30/10 minutes to 15/5 minutes in closed areas
тнХTesting till Ag negative to no testing to confirm when Ag will become negative
тнХFear to no or less fear
тнХMortality is two times that of the government figures reported
тнХFor every 1 tested people, there are 20 untested; for every 20 Covid patients, there are 80 patients with corona-like illness.
тнХStigma to less stigma
тнХLow mortality to high mortality amongst doctors
тнХIgnorance to knowledge
тнХEngineering (AII rooms) to social engineering (test for 5 parameters when screening - тАУ temperature (low grade, does not respond to paracetamol), SpO2 (happy hypoxia), loss of smell, loss of taste (give jaggery тАУ first taste to go is sweet taste) and hand grip strength)
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*New loss of smell and taste has been seen in 20-30% of patients; the disease is mild in nature*.
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*We now know that plasma therapy is effective if given early*.
If you are a Internal medicine specialist, and interested in CME INDIA whatsaap group,contact 9431122340(dr nk singh)