30/03/2026
ZMYND11::MBTD1 is an extremely rare but recurrent cytogenetic abnormality previously reported in approximately ten cases of acute myeloid leukemia (AML).
A new case series describes clinical and biological characteristics and suggests defining a new distinct subtype of AML with ZMYND11::MBTD1 rearrangement that may warrant recognition as a separate entity under the category of “other rare recurrent genetic abnormalities” in future AML classification systems.
https://haematologica.org/article/view/13008