Dott. Giovanni Salamano Studio Medico

Dott. Giovanni Salamano Studio Medico Da tre generazioni ci occupiamo della salute dei Vercellesi, come Medici di Famiglia dal 1921 ad ogg

 New in the November 27, 2025, issue of NEJM: ⁣⁣Early Discontinuation of Aspirin after PCI (TARGET-FIRST trial) ⁣⁣Early ...
29/11/2025

New in the November 27, 2025, issue of NEJM: ⁣

Early Discontinuation of Aspirin after PCI (TARGET-FIRST trial) ⁣

Early Withdrawal of Aspirin after PCI (NEO-MINDSET trial) ⁣

Daily Mosnodenvir as Dengue Prophylaxis ⁣

CRISPR-Cas9 Targeting ANGPTL3⁣

Engasertib in Hereditary Hemorrhagic Telangiectasia ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 Food allergy is increasingly prevalent in developed countries, affecting approximately 10% of children in the United St...
29/11/2025

Food allergy is increasingly prevalent in developed countries, affecting approximately 10% of children in the United States. Immune sensitization (based on the detection of IgE specific for food proteins) to peanuts, eggs, milk, sesame, tree nuts, or seafood is a risk factor for food allergy, although not all sensitized persons have a reaction on exposure. The clinical signs and symptoms of food allergy include oral pruritus, abdominal pain, diarrhea, laryngeal obstruction, urticaria, wheezing, and hypotension. They are attributable to the food protein–induced activation of mast cells and basophils. Mast cells and basophils are the major effector cells of IgE-driven immediate hypersensitivity; they generate or release potent vasoactive and bronchoconstricting mediators. In the most extreme situation, food allergy can result in systemic anaphylaxis, a rapid-onset life-threatening event that can induce cardiovascular or respiratory compromise due to widespread activation of mast cells and basophils. Food allergy accounts for 30 to 50% of anaphylaxis in the United States. Contemporary advances in the prevention and treatment of food allergy include the introduction of peanut protein to the diet early in life, Food and Drug Administration ()–approved oral peanut immunotherapy, and monoclonal antibodies against IgE to prevent it from binding to cells and eliciting responses. Nonetheless, food allergy continues to cause substantial illness and anxiety, and anaphylaxis due to inadvertent ingestion remains prevalent. Mechanistic insights and new approaches to the management of food allergy are urgently needed. Studies recently reported by Hoyt et al. and Bachtel et al. therefore come as welcome news. ⁣

Continue reading the Clinical Implications of Basic Research article “A New Stage for Seasoned Actors — Food Anaphylaxis and the Cysteinyl Leukotrienes,” from and , at NEJM.org (link in bio). ⁣

NEJM

 New in the November 20, 2025, issue of NEJM: ⁣⁣Potassium for High Risk of Ventricular Arrhythmias (POTCAST trial) ⁣⁣Red...
29/11/2025

New in the November 20, 2025, issue of NEJM: ⁣

Potassium for High Risk of Ventricular Arrhythmias (POTCAST trial) ⁣

Reducing Antihypertensive Drugs in Nursing Home Residents (RETREAT-FRAIL trial) ⁣

Efficacy and Safety of mRNA Influenza Vaccine (phase 3 trial) ⁣

Belzutifan for Pheochromocytoma or Paraganglioma (LITESPARK-015 phase 2 trial)⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 Pituitary tumors account for approximately 15% of intracranial neoplasms and may (in the case of macroadenomas, which h...
29/11/2025

Pituitary tumors account for approximately 15% of intracranial neoplasms and may (in the case of macroadenomas, which have a diameter >10 mm) cause compression of surrounding structures, as well as systemic symptoms. Acromegaly is the result of excess growth hormone secretion by generally benign adenomas arising in adult pituitary somatotrophs. Extrapituitary causes are exceedingly rare. The incidence of acromegaly is approximately 10 cases per 1 million persons. Roughly 20% of all pituitary tumors secrete growth hormone (somatotroph adenomas), and 95% appear to be sporadic, without known genetic causes. Approximately 25% of somatotroph adenomas also secrete prolactin. In a new article, Andrea Giustina, MD, and Annamaria Colao, MD, PhD, review current knowledge of the pathophysiology and pathogenesis of acromegaly, as well as its clinical features, diagnosis, treatment, and disease course, focusing on the general clinician’s key role in early diagnosis and management. ⁣

Read the Review Article “Acromegaly,” from , IRCCS San Raffaele Hospital (.raffaele), and , at NEJM.org (link in bio). ⁣

Otolaryngology Cardiology NEJM

 A new review by Andrea Giustina, MD, and Annamaria Colao, MD, PhD, updates the pathophysiology and disease course of ac...
29/11/2025

A new review by Andrea Giustina, MD, and Annamaria Colao, MD, PhD, updates the pathophysiology and disease course of acromegaly, focusing on the general clinician’s key role in early diagnosis and management. ⁣

At diagnosis, approximately 70% of patients with acromegaly have identifiable macroadenomas that may have grown laterally and extend into the cavernous sinus. In the large Liège Acromegaly Survey, physical changes were most often what led patients with acromegaly to seek medical evaluation and care, especially the development of dysmorphic facies (in 21.5% of cases), which were associated with macroglossia, dental diastema (gaps), mandibular overgrowth, and prognathism, and enlarged hands and feet (in 13.6%). Headache (in 7.5% of cases), asthenia (in 5.9%), and excess perspiration (in 2.0%) also led patients to seek care. Coexisting conditions noted at diagnosis included thyroid enlargement (in 34.0% of cases), hypertension (in 28.8%), diabetes (in 27.5%), sleep apnea (in 25.5%), and cardiac hypertrophy (in 15.5%) (seen in figure). ⁣

Learn more in the Review Article “Acromegaly,” from , IRCCS San Raffaele Hospital (.raffaele), and , at NEJM.org (link in bio). ⁣

Otolaryngology Cardiology NEJM

 New in the November 13, 2025, issue of NEJM: ⁣⁣Deferring Arterial Catheterization in Shock (EVERDAC trial) ⁣⁣Beta-Block...
29/11/2025

New in the November 13, 2025, issue of NEJM: ⁣

Deferring Arterial Catheterization in Shock (EVERDAC trial) ⁣

Beta-Blockers after MI without Reduced EF (REBOOT trial) ⁣

Beta-Blockers after Myocardial Infarction (BETAMI–DANBLOCK trial) ⁣

Sacituzumab Govitecan in Triple-Negative Breast Cancer (ASCENT-03 phase 3 trial) ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 New in the November 6, 2025, issue of NEJM: ⁣⁣Survival after Chest-Wall Irradiation in Breast Cancer (SUPREMO phase 3 t...
29/11/2025

New in the November 6, 2025, issue of NEJM: ⁣

Survival after Chest-Wall Irradiation in Breast Cancer (SUPREMO phase 3 trial)⁣

Oral Icotrokinra for Plaque Psoriasis (ICONIC-LEAD phase 3 trial) ⁣

Orforglipron, a GLP-1 Receptor Agonist for Obesity (ATTAIN-1 phase 3 trial) ⁣

Safety and Immunogenicity of Lassa Fever Vaccine⁣

Sevabertinib in HER2-Mutant NSCLC (SOHO-01 phase 1–2 study) ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 New in the October 30, 2025, issue of NEJM: ⁣⁣European Study of Prostate Cancer Screening⁣⁣Amivantamab–Lazertinib in 𝘌𝘎...
29/11/2025

New in the October 30, 2025, issue of NEJM: ⁣

European Study of Prostate Cancer Screening⁣

Amivantamab–Lazertinib in 𝘌𝘎𝘍𝘙-Mutated Advanced NSCLC (MARIPOSA phase 3 trial)⁣

Physical Therapy for Meniscal Tear and Knee Pain (TeMPO trial) ⁣

Safety and Efficacy of an S. Paratyphi A Vaccine (VASP phase 2b trial) ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 New in the October 23, 2025, issue of NEJM: ⁣⁣Hypertonic Saline or Carbocisteine in Bronchiectasis (CLEAR trial) ⁣⁣Aspi...
29/11/2025

New in the October 23, 2025, issue of NEJM: ⁣

Hypertonic Saline or Carbocisteine in Bronchiectasis (CLEAR trial) ⁣

Aspirin and Anticoagulation in Chronic Coronary Syndrome (AQUATIC trial) ⁣

Common Diseases in Clinical Cohorts ⁣

Sotatercept for Pulmonary Arterial Hypertension (HYPERION phase 3 trial) ⁣

2024–2025 Covid-19 Vaccine and U.S. Veterans ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 New in the October 16, 2025, issue of NEJM: ⁣⁣Sentinel-Node Biopsy in Cervical Cancer (PHENIX phase 3 trial) ⁣⁣Telitaci...
18/10/2025

New in the October 16, 2025, issue of NEJM: ⁣

Sentinel-Node Biopsy in Cervical Cancer (PHENIX phase 3 trial) ⁣

Telitacicept for Systemic Lupus Erythematosus (18C010 phase 3 trial) ⁣

Gene Therapy for Adenosine Deaminase Deficiency ⁣

Mass Azithromycin Administration to Infants in Mali (LAKANA trial) ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 New in the October 9, 2025, issue of NEJM: ⁣⁣Baxdrostat Efficacy and Safety in Uncontrolled Hypertension (BaxHTN phase ...
15/10/2025

New in the October 9, 2025, issue of NEJM: ⁣

Baxdrostat Efficacy and Safety in Uncontrolled Hypertension (BaxHTN phase 3 trial)⁣

Nexiguran Ziclumeran in ATTR with Polyneuropathy⁣

Targeted Indoor Spraying to Prevent Aedes-Borne Diseases⁣

Permethrin-Treated Wraps for Prevention of Malaria⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

 New in the October 2, 2025, issue of NEJM: ⁣⁣Intravenous Rehydration for Severe Acute Malnutrition (GASTROSAM trial) ⁣⁣...
15/10/2025

New in the October 2, 2025, issue of NEJM: ⁣

Intravenous Rehydration for Severe Acute Malnutrition (GASTROSAM trial) ⁣

Medical Imaging and Pediatric Hematologic Cancer Risk ⁣

Olezarsen in Moderate Hypertriglyceridemia (Essence–TIMI 73b phase 3 trial)⁣

Clesrovimab to Prevent RSV Disease in Healthy Infants (CLEVER phase 2b–3 trial)⁣

Home-Based Care for Hypertension in South Africa (IMPACT-BP trial) ⁣

Visit NEJM.org for the latest medical research and tap the link in our bio to subscribe. ⁣

Indirizzo

Piazza Solferino N. 3
Vercelli
13100

Orario di apertura

Lunedì 17:00 - 19:00
Martedì 17:00 - 19:00
Mercoledì 10:00 - 12:00
Giovedì 10:00 - 12:00
Venerdì 17:00 - 19:00

Telefono

+393345713761

Sito Web

https://www.miodottore.it/

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A little help to Health in rural town.

Da tre generazioni lo Studio Medico Salamano si occupa della salute de

i pazienti Vercellesi. Zona posta tra le metropoli di Torino e Milano esattamente a metà strada tra le due città più importanti del Nord Italia è famosa nel mondo agricolo per la presenza della risicoltura resa possibile da Camillo Benso Conte di Cavour, primo ministro del Regno Sabaudo che qui regnava. La presenza del fiume Po e dei suoi maggiori affluenti dalle Alpi che circondano il Piemonte ha reso possibile nei primi dell’800 la costruzione di canali che permettono una abbondante irrigazione di queste terre, prima paludose e bonificate dai Monaci Cistercensi nell’epoca Medioevale intorno al 1200 - 1300 fondando importanti Abazie che facevano capo all’Arcidiocesi di Vercelli. Proprio a causa della posizione immersa nella pianura padana e nel suo clima afoso d’estate e nebbioso d’inverno, questa regione ha una insolitamente elevata percentuale di pazienti sofferenti di osteopatie ( i cosiddetti Reumatismi ) e malattie infettive dell’apparato respiratorio. Recentemente con l’aumento della vita media grazie ai progressi principalmente in capo cardiovascolare si sta assistendo ad un aumento quasi esponenziale dei casi di neoplasie dell’albero respiratorio, dell’apparato gastroenterico e urinario. Il problema dell’inquinamento atmosferico è in questa zona particolarmente evidente per le scarse correnti di aria che possano pulire e rinnovare l’aria ed il puvuscolo atmosferico stagnante in questa regione nonostante sia a carattere rurale e non industriale come le vicine Torino e Milano. Un particolare evidente nel recente passato è la particolare incidenza di Leptospirosi dovuta alla presenza di acqua stagnante nelle risaie dove le contadine lavoravano a piedi scalzi. Tuttavia anche l’artrite reumatoide e le malattie reumatiche in genere hanno una elevata incidenza tanto che fino a pochi anni fa nell’’Ospedale Sant’Andrea di Vercelli era presente un reparto di Reumatologia ( uno dei pochi in Italia e purtroppo recentemente eliminato ). Per tali motivi prima mio nonno Giovanni Dott Salamano ( Nino ) poi mio padre Andre Dott Salamano ed infine il sottoscritto Giovanni Dott Salamano abbiamo dedicato la nostra ”vita“ alla cura ed allo studio delle malattie infettive ( Nonno Nino ), Reumatiche ( papà Andrea ) ed osteometaboliche ( il sottoscritto ), pur mantenendo l’attenzione sulla Medicina Generale che il Medico di Famiglia deve saper affrontare.