Neuron Guard Srl

22/04/2026

🧠 𝐍𝐞𝐰 𝐩𝐞𝐞𝐫-𝐫𝐞𝐯𝐢𝐞𝐰𝐞𝐝 𝐞𝐯𝐢𝐝𝐞𝐧𝐜𝐞 𝐬𝐮𝐩𝐩𝐨𝐫𝐭𝐢𝐧𝐠 𝐭𝐚𝐫𝐠𝐞𝐭𝐞𝐝 𝐛𝐫𝐚𝐢𝐧 𝐜𝐨𝐨𝐥𝐢𝐧𝐠 𝐝𝐮𝐫𝐢𝐧𝐠 𝐡𝐢𝐠𝐡-𝐫𝐢𝐬𝐤 𝐜𝐚𝐫𝐝𝐢𝐚𝐜 𝐬𝐮𝐫𝐠𝐞𝐫𝐲 🧠

A single-center study published in Perfusion Journal investigated the use of our Aurora head–neck cooling device during open pulmonary endarterectomy (PEA), a procedure carrying significant risk of neurological complications due to prolonged circulatory arrest.

𝐊𝐞𝐲 𝐟𝐢𝐧𝐝𝐢𝐧𝐠𝐬:
→ Cerebral desaturation events (rSO₂ < 40%) occurred in 22.2% of Aurora patients vs. 77.8% of controls (p = 0.030)
→ Postoperative NSE levels showed a favorable trend in the Aurora group
→ Dual-modality cooling, combining systemic hypothermia with targeted head–neck cooling, improved intra-operative cerebral oxygenation

These results add to the growing body of evidence supporting targeted temperature management as a neuroprotective strategy in cardiac surgery.

📄 Read the full publication: https://doi.org/10.1177/02676591261429813

Background Open pulmonary endarterectomy (PEA) carries a high risk of neurological complications due to cerebral hypoperfusion and ischemia–reperfusion injury. ...

16/04/2026

𝐁𝐫𝐚𝐢𝐧 𝐭𝐢𝐬𝐬𝐮𝐞 𝐩𝐞𝐫𝐟𝐮𝐬𝐢𝐨𝐧 𝐝𝐮𝐫𝐢𝐧𝐠 𝐩𝐮𝐥𝐦𝐨𝐧𝐚𝐫𝐲 𝐞𝐧𝐝𝐚𝐫𝐭𝐞𝐫𝐞𝐜𝐭𝐨𝐦𝐲 - 𝐓𝐡𝐞 𝐢𝐦𝐩𝐚𝐜𝐭 𝐨𝐟 𝐜𝐨𝐧𝐭𝐫𝐨𝐥𝐥𝐞𝐝 𝐫𝐞𝐠𝐢𝐨𝐧𝐚𝐥 𝐜𝐨𝐨𝐥𝐢𝐧𝐠 | 𝐍𝐞𝐰 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐞𝐯𝐢𝐝𝐞𝐧𝐜𝐞 𝐬𝐮𝐩𝐩𝐨𝐫𝐭𝐢𝐧𝐠 𝐭𝐚𝐫𝐠𝐞𝐭𝐞𝐝 𝐛𝐫𝐚𝐢𝐧 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐮𝐫𝐞 𝐦𝐚𝐧𝐚𝐠𝐞𝐦𝐞𝐧𝐭 𝐰𝐢𝐭𝐡 𝐨𝐮𝐫 𝐝𝐞𝐯𝐢𝐜𝐞 𝐂𝐁𝟐𝟒𝟎_𝐀𝐮𝐫𝐨𝐫𝐚

We are pleased to highlight results from a clinical study conducted at the Fondazione I.R.C.C.S. Policlinico San Matteo Pavia, published in Perfusion, evaluating innovative approaches to brain-targeted temperature control in patients at risk of acute brain injury.

Open pulmonary endarterectomy (PEA) carries a high risk of neurological complications due to cerebral hypoperfusion and ischemia–reperfusion injury. Systemic cooling during extracorporeal circulation may not sufficiently reduce brain temperature. Combining systemic and targeted head–neck cooling may enhance neuroprotection.

Dual-modality cooling combining extracorporeal hypothermia and targeted head–neck cooling improved intraoperative cerebral oxygenation and were associated with lower postoperative NSE levels.

These results align with Neuron Guard’s mission to develop portable and precise solutions for brain protection, designed to bring early neuroprotection directly to the point of care.

We thank the clinical teams at the Fondazione I.R.C.C.S. Policlinico San Matteo Pavia for their contribution to advancing research in neurocritical care.

🔗 Read the study: https://doi.org/10.1177/02676591261429813

02/02/2026

✅ 𝐁𝐁𝐂 - 𝐁𝐫𝐚𝐢𝐧 𝐜𝐨𝐨𝐥𝐢𝐧𝐠 𝐜𝐨𝐥𝐥𝐚𝐫 𝐭𝐫𝐢𝐚𝐥 𝐟𝐨𝐫 𝐡𝐞𝐚𝐝 𝐢𝐧𝐣𝐮𝐫𝐲 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬 ✅

We are pleased to share a significant feature by BBC News highlighting the world-first clinical study of Neuron Guard’s brain cooling collar, an innovative approach to targeted cerebral temperature management designed to improve outcomes for patients with severe traumatic brain injury.

Cambridge University Hospitals NHS Foundation Trust, which runs Addenbrooke’s Hospital, said it would be the "𝒘𝒐𝒓𝒍𝒅'𝒔 𝒇𝒊𝒓𝒔𝒕 𝒊𝒏-𝒉𝒖𝒎𝒂𝒏 𝒔𝒕𝒖𝒅𝒚" 𝒕𝒐 𝒎𝒆𝒂𝒔𝒖𝒓𝒆 𝒕𝒉𝒆 "𝒑𝒊𝒐𝒏𝒆𝒆𝒓𝒊𝒏𝒈 𝒎𝒆𝒅𝒊𝒄𝒂𝒍 𝒅𝒆𝒗𝒊𝒄𝒆".

We extend our sincere gratitude to Dr. Andrea Lavinio, our Clinical Lead, for his unwavering leadership and clinical expertise in advancing this pioneering research. His contribution has been instrumental in bringing international attention to this important study and furthering our mission to transform care for patients with acute brain injury.

We encourage you to read the interview and learn more about the potential impact of this cutting-edge technology in neuro-critical care.

A leading hospital is testing a new device aimed at reducing swelling after a brain injury.

19/04/2024

🔜 See you in Rome for the latest edition of 𝗜𝘁𝗮𝗹𝘆 𝗛𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗦𝘂𝗺𝗺𝗶𝘁 𝟮𝟬𝟮𝟰

At , Italian healthcare stakeholders will share insights and best practices to elevate the nation's healthcare system.

The summit will give us the opportunity to connect with key healthcare decision-makers and be part of the conversations that shape the future of healthcare.

🎟 Information and tickets: https://bamberghealth.com/event/italy-healthcare-innovation-summit-2024

📅 April 23rd
📍 Hotel Shangri-La Roma by OMNIA hotels

09/04/2024

𝐓𝐫𝐚𝐧𝐬𝐟𝐨𝐫𝐦𝐢𝐧𝐠 𝐈𝐂𝐔'𝐬 𝐏𝐚𝐭𝐢𝐞𝐧𝐭 𝐂𝐚𝐫𝐞 𝐰𝐢𝐭𝐡 𝐚 𝐬𝐮𝐬𝐭𝐚𝐢𝐧𝐚𝐛𝐥𝐞 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐮𝐫𝐞 𝐦𝐚𝐧𝐚𝐠𝐞𝐦𝐞𝐧𝐭 𝐝𝐞𝐯𝐢𝐜𝐞 - written by Enrico Giuliani for Bamberg Health

Introducing a new medical device for targeted temperature management in the Intensive Care Unit (ICU) requires a meticulous approach that prioritizes sustainability in both economic and environmental aspects.

With our medical device CB240_AURORA, we approached the temperature management challenge from a different angle adopting technologies that were used in other sectors and adapting them to a medical application. These technologies are more energy efficient and can be produced locally with additive manufacturing techniques.

Read more in the article below.

Introducing a new medical device for targeted temperature management in the Intensive Care Unit (ICU) requires a meticulous approach that prioritizes sustainability in both economic and environmental aspects.

21/02/2024

Latest news: “National brain and spinal injury research centre to open in Cambridge”

A new centre will open in April to improve care for people with brain and spinal injuries.
The Cambridge HealthTech Research Centre, based at Addenbrooke's Hospital, will develop technology to help both treatment and recovery.
It is one of 14 across England working on solutions for different conditions.

(..) Companies like Cambridge-based NeuronGuard Ltd, will be working with the centre.

"It is effective," said Andrea Lavinio, a neurocritical care consultant at Addenbrooke's. "But it chills the whole body which can lead to chest infections."
NeuronGuard has developed an alternative which is in early trials - a neck collar which only cools the blood as it enters the brain.
Unlike the existing treatment, it is portable enough to be used at the scene of an accident.

Read the full article by BBC 👉 https://www.bbc.com/news/uk-england-cambridgeshire-68278550

There are 14 HealthTech Centres across England, each working on solutions for different conditions.

24/11/2023

Neuron Guard has completed a successful surveillance audit and obtained the ISO Certification 13485.

The certificate of conformity of the company's quality management system to the requirements of - concerns aspects related to Medical Devices - has been released by IMQ S.p.A..

We are committed to collaborating with relevant stakeholders to identify the needs and adapt our product to make it as usable and effective as possible and compliant with all relevant regulations.

28/07/2023

🟣 A Novel Technology for Targeted Brain Temperature Management 🟣 We're thrilled to announce the publication of the first-in-human study on Neurocritical Care❗

Our group has developed a technology - CB240_Aurora - that allows selective brain temperature management with a highly portable device, thus maximizing neuroprotection while minimizing systemic side effects. Thanks to its portability, the technology may also allow the early application of TTM in out-of-hospital settings (i.e., ambulances) and continuity of care when patients are transferred out of the ICU for imaging or emergency surgery.

Here, we report the first-in-human study of the technology, sponsored by a grant from the National Institute for Health and Care Research Brain Injury MedTech Co-operative.

⬇ Full article ⬇

https://link.springer.com/article/10.1007/s12028-023-01800-7

Special thanks to Andrea Lavinio, Erta Beqiri, Ketan Kataria!

28/05/2022

Da non perdere questo tra la nostra cofondatrice e CMO Mary Franzese con Barbara Sala, CEO di Delcon.

12/05/2022

It was a pleasure for us to participate in this mission.

Thank you all for taking us on board and making it real.

Looking forward to the next adventure!

D-Air Lab Eurac Research terraXcube