18/02/2026
Focusing on Multiple Sclerosis (MS) and Epilepsy highlights why the "3D" aspect of Cube is such a game-changer. These conditions often hide in the "nooks and crannies" of the brain that standard scans might overlook.
1. Multiple Sclerosis (MS)
In MS, the goal is to find "plaques" (areas of inflammation or scarring). 3D FLAIR Cube is the gold standard for this for two main reasons:
Juxtacortical Lesions: These are tiny spots located right at the boundary between the gray matter and white matter. In 2D scans, these often get "blurred" into the surrounding tissue. Cube’s sub-millimeter thinness makes these spots pop.
Lesion Load Tracking: Because there are no gaps between slices, doctors can more accurately calculate the total volume of all lesions. This is crucial for seeing if a medication is actually working or if the disease is progressing.
2. Epilepsy
For patients with seizures, the culprit is often Focal Cortical Dysplasia (FCD)—a tiny area where the brain didn't form quite right.
Finding the "Needle in the Haystack": FCD can be incredibly subtle. 3D Cube allows radiologists to "scroll" through the brain in the coronal plane (front to back) and the axial plane (top to bottom) simultaneously.
Curving the Image: Specialized software can take the 3D Cube data and "unfold" the curves of the brain (cortical reconstruction). This allows doctors to see if the thickness of the brain's "crust" (the cortex) is abnormal, which is a major red flag for epilepsy.