09/12/2025
Researchers at AMC, led by Professor Jung-Hoon Park of the Department of Convergence Medicine and Professor Do Hoon Kim of the Division of Gastroenterology at AMC, have developed a novel photodynamic therapy system that uses a photosensitizer-coated stent to deliver repeated laser treatment directly to esophageal tumors. Unlike conventional therapy, which spreads the photosensitizer systemically and limits treatment depth, this system allows uniform, localized irradiation and maximizes treatment efficiency. ๐จโ๏ธ๐ฉบโก๏ธ
Tests in a porcine esophagus model showed that repeated treatments effectively destroyed cancer cells, reached deeper tissue layers, and minimized complications. The stent can be immediately retrieved after each procedure, reducing risks and enabling repeated localized therapy, even for patients with multiple lesions. ๐ฅ๐
The study highlights a promising minimally invasive option for esophageal cancer treatment and was recently published in the international journal โBiomaterials Researchโ. ๐งฌ๐ฌ
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โฒย (From left) Professor Jung-Hoon Park from the Department of Convergence Medicine and Professor Do Hoon Kim from the Division of Gastroenterology at Asan Medical Center