Medi Clini Lab Pharmaco Guide

Medi Clini Lab Pharmaco Guide Medical laboratory technology ,Med.clinical ,Pharmological informations.

𝐏𝐘𝐔𝐑𝐈𝐀 𝐜𝐚𝐮𝐬𝐞𝐬Pyuria refers to the presence of elevated white blood cells (pus cells) in the urine, often making it appea...
09/12/2025

𝐏𝐘𝐔𝐑𝐈𝐀 𝐜𝐚𝐮𝐬𝐞𝐬

Pyuria refers to the presence of elevated white blood cells (pus cells) in the urine, often making it appear cloudy.[1]

# # Common Infectious Causes
Urinary tract infections (UTIs) are the most frequent cause, affecting the bladder, urethra, kidneys, or ureters.[1] Sexually transmitted infections like gonorrhea or chlamydia, as well as tuberculosis and fungal infections, can also lead to pyuria.[3][5]

# # Sterile Pyuria Causes
Sterile pyuria occurs without detectable bacteria on standard cultures and may stem from atypical infections (e.g., viruses, parasites like trichomoniasis), kidney stones, prostatitis, or interstitial cystitis.[1][3] Noninfectious factors include autoimmune diseases (e.g., lupus), medications (e.g., NSAIDs, antibiotics), and conditions like polycystic kidney disease or tumors.[3][5]

# # Other Risk Factors
Drug-induced reactions, recent catheter use, or systemic issues like sepsis and pneumonia contribute in some cases.[1][3] Diagnosis typically involves urinalysis and culture to differentiate causes.[3]

Pyuria is an elevated number of white blood cells in the urine, which can cause the urine to appear cloudy or contain pus. In this article, learn about the common causes, including urinary tract infections and sexually transmitted infections, as well as what symptoms to expect. We also cover the tre...

08/12/2025
𝖲𝖾𝗏𝖾𝗋𝖾 𝖺𝖻𝖽𝗈𝗆𝗂𝗇𝖺𝗅 𝗉𝖺𝗂𝗇 𝗐𝗂𝗍𝗁  𝗌𝖾𝗏𝖾𝗋𝖾 𝖼𝗈𝗇𝗌𝗍𝗂𝗉𝖺𝗍𝗂𝗈𝗇 𝖼𝖺𝗎𝗌𝖾𝗌Severe abdominal pain combined with severe constipation often sign...
07/12/2025

𝖲𝖾𝗏𝖾𝗋𝖾 𝖺𝖻𝖽𝗈𝗆𝗂𝗇𝖺𝗅 𝗉𝖺𝗂𝗇 𝗐𝗂𝗍𝗁 𝗌𝖾𝗏𝖾𝗋𝖾 𝖼𝗈𝗇𝗌𝗍𝗂𝗉𝖺𝗍𝗂𝗈𝗇 𝖼𝖺𝗎𝗌𝖾𝗌

Severe abdominal pain combined with severe constipation often signals a medical emergency, such as bowel obstruction or f***l impaction, requiring immediate evaluation in an emergency department.[1][2]

# # Emergency Causes
Bowel obstruction blocks the intestine, preventing stool passage and causing cramping pain, bloating, vomiting, and no gas or bowel movements; common triggers include adhesions from prior surgery, tumors, hernias, or diverticulitis.[3][4][5] F***l impaction involves hardened stool buildup, leading to abdominal distension, pain, and potential overflow diarrhea, especially in those with chronic constipation or immobility.[6][7][8] Other critical issues like intestinal perforation or stercoral colitis can arise from untreated impaction, producing sudden intense pain, fever, and rigid abdomen.[9][10][11]

# # Non-Emergency Causes
Conditions such as irritable bowel syndrome, medications (e.g., opioids, anticholinergics), hypothyroidism, or inflammatory bowel disease can cause crampy pain and constipation but typically lack the acute severity.[12][13][14] Lifestyle factors like dehydration, low fiber, or inactivity contribute to secondary constipation with milder pain.[12][15]

Seek urgent care if pain persists, worsens, or includes vomiting, fever, blood in stool, or swelling, as delays risk perforation 𝗉𝗈𝗌𝗌𝗂𝖻𝗅𝖾.
Most common causes of bowel obstruction in adults

The most common causes of bowel obstruction in adults are adhesions from prior surgery, hernias, and colorectal cancer.[6][5][7]

# # Small Bowel Obstruction
Adhesions account for 55-75% of cases, often forming after abdominal or pelvic surgeries like appendectomy or colorectal procedures.[1][4][5] Hernias, particularly incarcerated groin hernias, cause 10-20% of obstructions by trapping intestinal loops.[6][5] Other contributors include Crohn's disease leading to strictures, malignancies, and volvulus.[1][5]

# # Large Bowel Obstruction
Colorectal cancer is the leading cause, responsible for about 60% of cases, often presenting as an emergency in 40% of affected patients.[1][3][4] Diverticulitis and sigmoid volvulus each account for around 15% of cases, with inflammatory bowel disease and adhesions also common.[1][3][7] F***l impaction or strictures from prior inflammation add to risks in older adults.[1][3]

𝖳𝖤𝖲𝖳𝖲 𝖥𝖮𝖱 𝖳𝖴𝖬𝖮𝖴𝖱𝖲 𝖨𝖭 𝖳𝖧𝖤 𝖡𝖱𝖠𝖨𝖭𝖳𝖾𝗌𝗍𝗌 𝖿𝗈𝗋 𝗍𝗎𝗆𝗈𝗎𝗋 𝗂𝗇 𝗍𝗁𝖾 𝖻𝗋𝖺𝗂𝗇Tests for brain tumors primarily include imaging, biopsy, and...
01/12/2025

𝖳𝖤𝖲𝖳𝖲 𝖥𝖮𝖱 𝖳𝖴𝖬𝖮𝖴𝖱𝖲 𝖨𝖭 𝖳𝖧𝖤 𝖡𝖱𝖠𝖨𝖭
𝖳𝖾𝗌𝗍𝗌 𝖿𝗈𝗋 𝗍𝗎𝗆𝗈𝗎𝗋 𝗂𝗇 𝗍𝗁𝖾 𝖻𝗋𝖺𝗂𝗇

Tests for brain tumors primarily include imaging, biopsy, and specialized fluid analysis. Common imaging tests are MRI (magnetic resonance imaging), CT (computed tomography) scan, and PET-CT scan, which help visualize the tumor's size, location, and characteristics. Biopsy, which involves taking a tissue sample from the brain tumor, is critical for diagnosing the tumor type. Additional tests may include a neurological exam, lumbar puncture to examine cerebrospinal fluid, and brain angiogram to view blood vessels supplying the tumor.

Detailed types of MRI scans include contrast-enhanced MRI, magnetic resonance spectroscopy (MRS) that examines chemical changes in the tumor, perfusion MRI to evaluate blood flow, and functional MRI (fMRI) which detects brain activity. CT scans are useful when MRI is not possible or for emergency evaluations. PET-CT and SPECT scans can help differentiate tumor growth from treatment effects.

Brain tumor diagnosis may also involve molecular testing of biopsy samples for guiding treatment options. Blood tests, while they cannot diagnose brain tumors directly, may detect hormones or chemicals released by some tumors. Neuroendoscopy can be used for biopsy in specific brain regions.

In summary, standard tests for brain tumors include:
- MRI and CT scans for imaging the tumor
- Biopsy for histopathological diagnosis
- Lumbar puncture for cerebrospinal fluid analysis (in some cases)
- Brain angiogram for vascular imaging
- Molecular and specialized MRI techniques to understand tumor characteristics better[1][2][4][5][6

ඉරුවාරදය (Migraine) කියන්නේ , ඉරුවාරදය කියන රෝගී තත්ත්වයට මුහුන දුන්න රෝගියෙකුට අහන්නට තරම් ප්‍රිය වචනයක් නොවේ. බොහෝ විට...
24/11/2025

ඉරුවාරදය (Migraine) කියන්නේ , ඉරුවාරදය කියන රෝගී තත්ත්වයට මුහුන දුන්න රෝගියෙකුට අහන්නට තරම් ප්‍රිය වචනයක් නොවේ. බොහෝ විට මිග්‍රේන් කියන්නේ එතරම් වේදනාකාරී සහ අප්‍රිය සහගත අත්දැකීමක්.

ඔබ ඕනැම කෙනෙක් ඉදහිට විවිධ හිසේ අමාරු වලට මුහුණ දී තිබුනත් Migraine කියන්නේ ඊට එහා ගිය ඉතාම ඉහල වේදනාවක් ඇති කරන , ඒ වගේම රෝගියාගේ දෛනික ජීවිතය සම්පූර්ණයෙන්ම උඩු යටිකුරු කරන්නට සමත් හිසේ කැක්කුමක් කීවොත් මම නිවැරදියි. මෙයට හේතුව තමයි අපි එදිනෙදා මුහුනදෙන හිසේ කැක්කුමකට එහා ගිහින් දින ගනනක් , සති ගනනක් එක දිගට පවතින හිසේ කැක්කුමක් විදියට පවා මෙම රෝගී තත්ත්වය වර්ධනය වෙන්න පුලුවන්

මිග්‍රේන් (Migraine) රෝගය ගත්තාම ඉතාව ඉහල රෝගින් ප්‍රතිශතයක් වාර්තා වෙනවා. උදාහරණයක් වශයෙන් ඇමරිකාවේ 12%කට පමණ ඉරුවාරදය රෝගය පවතින බව හඳුනාගෙන තියෙනවා. ඒ එක්කම ශ්‍රි ලංකාව ගත්තාම දැනට මේ පිලිබඳ සමීක්ෂණ වර්තා නොපවතින අතර පේරාදෙණිය විශ්වවිද්‍යාලය මගින් සිදුකල සමීක්ෂණයකට අනුව විශ්වවිද්‍යාල සිසුන්ගෙන් 50%කට පමණ මිග්‍රේන් සහ එවැනි රෝග ලක්ෂණ පවතින බව හඳුනාගෙන තියෙනවා. ඒ එක්කම මානසික ආතතිය විශාදය වැනි මානසික රෝග, ජීවන රටාවේ වෙනස්කම්, දීර්ඝ ගමන් වැනි කරුණු වලිනුත් මෙම රෝගය වර්ධනය වෙන්නට පුලුවන්.

ඒ එක්කම මෙය නව යොවුන් වියේ සිටින දරුවන් අතර ඉතා සුලභ රෝගී තත්ත්වයක් කියලා කියන්න පුලුවන්.

ඉරුවාරදය යනු කුමක්ද..? (Migraine?)
ඉරුවාරදය යනු පැය කිහිපයක් එකදිගට පවතින හිසරදයකට (headache) සමාන තත්ත්වයකි. එය බොහෝ විට හිසේ එක් පැත්ත්කට සීමා වේ. තවද වමනය ආලොකයට හා ශබ්ද වලට ඇති අකමැත්ත වැනි ලක්ෂණද මේ සමග ඇති වෙනවා.

migraine in Sinhala
ඉරුවාරදය ඇතිවීමට හේතු මොනවාද..?
මෙය තවමත් නිශ්චිතව පැහැදිලි කර නැති නමුත් මේ සදහා බලපෑම් කලහැකි හේතු කිහිපයක් හදුනාගෙන ඇත.

ජානමය කරුණු
අධික මානසික ආතතිය
සමහර ආහාරමය හේතු
සමහර ඖෂධ
අප්‍රසන්න ශබ්ද වලට අනාවරනය වීම
අධික ආලොකයට ආනාවරනය වීම
මොළය ආශ්රිතව ඇතිවන ප්‍රශ්න
ඉරුවාරදය කාන්තාවන් අතර වැඩිපුර දක්නට ලැබෙන්නේ ඇයි..?
ශ්‍රී ලංකාව වගේම ලෝකයේ විවිධ ප්‍රදේශ සහ පලාත් වල සිදුකල පර්යේෂණ වලට අනුව ඉරුවාරදය රෝගය සඳහා පිරිමින්ට වඩා කාන්තාවන් ගොදුරුවීම වැඩි බව හඳුනාගෙන තියෙනවා. මෙයට හේතු බොහොමයක් තියෙන්න පුලුවන්. උදාහරණයක් විදියට සමහර කාන්තාවන් උපත් පාලන පෙති භාවිතා කරනවා. මෙම පෙති නිසා මිග්‍රේන් එන්න පුලුවන්.

𝗅𝗂𝗌𝗍 𝗈𝖿 𝗅𝖺𝖻 𝗍𝖾𝗌𝗍𝗌 𝖽𝗈𝗇𝖾 𝖿𝗈𝗋 𝖽𝗂𝖺𝖻𝖾𝗍𝗂𝖼𝗌𝖻𝖺𝗌𝗂𝖼 𝗍𝗈 𝗌𝗉𝖾𝖼𝗂𝖺𝗅 𝗍𝖾𝗌𝗍𝗌Laboratory tests for diabetics range from basic to more specia...
17/11/2025

𝗅𝗂𝗌𝗍 𝗈𝖿 𝗅𝖺𝖻 𝗍𝖾𝗌𝗍𝗌 𝖽𝗈𝗇𝖾 𝖿𝗈𝗋 𝖽𝗂𝖺𝖻𝖾𝗍𝗂𝖼𝗌
𝖻𝖺𝗌𝗂𝖼 𝗍𝗈 𝗌𝗉𝖾𝖼𝗂𝖺𝗅 𝗍𝖾𝗌𝗍𝗌

Laboratory tests for diabetics range from basic to more specialized tests used for diagnosis, monitoring, and managing diabetes. Here is a comprehensive list:

Basic Lab Tests for Diabetes:
- Fasting Blood Sugar (FBS) Test: Measures blood glucose after fasting for at least 8 hours.
- Random Plasma Glucose Test: Blood sugar test at any time of day, regardless of last meal.
- Oral Glucose Tolerance Test (OGTT): Measures blood sugar after fasting and then again after drinking a glucose-rich drink.
- Hemoglobin A1c (HbA1c) Test: Measures average blood glucose over the past 2-3 months; does not require fasting.
- Postprandial Glucose Test: Measures blood sugar after a meal to see how the body processes sugar.

Specialized or Additional Tests:
- C-Peptide Test: Indicates how much insulin the body is producing by measuring C-peptide levels in the blood; helps differentiate type 1 from type 2 diabetes.
- Insulin Autoantibodies (IAA): Tests for antibodies against insulin, useful in type 1 diabetes diagnosis.
- Electrolytes Panel: Sodium, potassium, chloride, bicarbonate levels to assess overall metabolic status.
- Diabetes Risk Panels: May include lipid profile (cholesterol, HDL, LDL, triglycerides) and other markers to assess cardiovascular risk.
- Fructosamine Test: Measures average blood glucose over the past 2-3 weeks, sometimes used if HbA1c is not reliable.
- Tests for Autoimmune Conditions: For type 1 diabetics, screening for other autoimmune disorders like celiac disease (e.g., IgA-tissue transglutaminase antibodies).
- Hepatic and Renal Function Panels: To monitor organs commonly affected by diabetes complications.

Important Lab Tests for Diabetes Patients such as: HbA1C, Fasting Blood Sugar Test, C-Peptide, Post Prandial Glucose Test etc.

𝖡𝗅𝗈𝗈𝖽 𝗍𝖾𝗌𝗍𝗌 𝖿𝗈𝗋 𝗏𝖾𝗋𝗂𝖼𝗈𝗌𝖾 𝗏𝖾𝗂𝗇𝗌  𝗐𝗂𝗍𝗁 𝖼𝖾𝗅𝗅𝗎𝗅𝗂𝗍𝗂𝗌For blood tests in varicose veins with cellulitis, the key focus is on id...
14/11/2025

𝖡𝗅𝗈𝗈𝖽 𝗍𝖾𝗌𝗍𝗌 𝖿𝗈𝗋 𝗏𝖾𝗋𝗂𝖼𝗈𝗌𝖾 𝗏𝖾𝗂𝗇𝗌 𝗐𝗂𝗍𝗁 𝖼𝖾𝗅𝗅𝗎𝗅𝗂𝗍𝗂𝗌

For blood tests in varicose veins with cellulitis, the key focus is on identifying infection and inflammation, as well as assessing complications related to venous insufficiency.

# # # Blood Tests for Cellulitis
- White blood cell count (WBC) typically elevated, indicating infection.
- Blood cultures may be done if systemic infection or bacteremia is suspected.
- C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) help assess severity and monitor response to treatment.
- Blood glucose testing to rule out diabetes, which can predispose to recurrent cellulitis or poor healing.
- In more severe cases, kidney function tests (creatinine), and electrolytes may be checked due to systemic involvement or antibiotic use [1][2][3].

# # # Tests for Varicose Veins Complications
- Duplex ultrasound Doppler is the primary imaging test to evaluate venous insufficiency, vein valve function, and to rule out deep vein thrombosis (DVT).
- Blood tests do not directly diagnose varicose veins but are important when complications such as cellulitis occur.
- Monitoring for inflammation and possible clotting abnormalities may involve general blood tests if the clinical scenario merits [4][5][6].

# # # Summary
In cases of varicose veins complicated by cellulitis, blood tests mainly target infection and inflammation markers (WBC, CRP, blood cultures), as well as underlying conditions like diabetes. Imaging like Doppler ultrasound is crucial for assessing the venous system itself.

This combination helps guide treatment and monitor for serious complications such as systemic infection or thrombosis [1][7][2].

If further specific testing guidance is needed, it can be provided.

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