26/11/2025
Many solid tumors are “cold”—fibrotic, poorly perfused, and hard for T cells to enter—so even breakthrough immunotherapies can stall. Two well-known, generally safe generics—metformin (for type-2 diabetes) and losartan (an angiotensin-receptor blocker for blood pressure)—have emerging evidence that they can remodel the tumor microenvironment and synergize with immunotherapy.
Read the full article below:
https://immunocine.com/metformin-losartan-everyday-medicines-that-may-help-warm-up-cold-tumors-for-immunotherapy/