Dr. Rogelio Guajardo, Psiquiatra y Psicoterapeuta

07/08/2025

19/07/2025

Genetic Link Between Cannabis Use Disorder and Mental Health

As cannabis becomes increasingly legal and accessible, its impact on mental health remains debated.

This study combined multiple genetic methods to assess how cannabis use and CanUD relate to psychiatric conditions.

CanUD, but not casual use, showed strong genetic correlations and causal links with disorders like ADHD, schizophrenia, and PTSD.

The study revealed shared genetic regions and biological pathways underlying these associations, offering insights into mechanisms of vulnerability.

Structural modeling confirmed that CanUD clusters genetically with other externalizing and psychiatric traits.

These results caution that heavy cannabis use may exacerbate psychiatric risks rather than alleviate them.

https://neurosciencenews.com/genetics-cud-mental-health-29485/

19/07/2025

Hace unos días me encontré con un artículo en una revista de terapeutas DBT que no conocía: DBT Bulletin, una publicación con artículos muy interesantes

17/07/2025

Neurons Store Backup Energy to Power the Brain Under Stress

Traditionally, neurons were thought to rely entirely on glial cells for stored energy.

New research reveals neurons themselves carry glycogen reserves that they use when their primary energy pathways falter.

The team used live imaging in worms to watch neurons adapt under oxygen deprivation, identifying a key enzyme that enables this process.

This discovery, termed “glycogen-dependent glycolytic plasticity,” shows neurons can independently adapt to stress.

Such metabolic flexibility may help preserve brain function during injury or disease.

The study opens doors to therapies targeting energy resilience in neurons.

15/04/2025

Cerro Monserrate, Bogotá 2025