30/07/2020
⚠️⚠️A lethal fungal infection led to an extensive necrosis of facial tissue necessitating a HUGE free-flap skin graft from thigh to cover the defect!!
Swipe left ⬅️ to see the pre-grafting images!! 💀⚠️
Mucormycosis is a rare invasive fungal infection caused by various opportunistic fungi of the Mucoraceae family. Considered 100% fatal in 1960, previous the introduction of amphotericine, Today the mortality ranges from 30-90% of all cases.
Mucormycosis is characterized by tissue necrosis due to an invasion of blood vessels and subsequent thrombosis, which usually follows a rapid progression.
The key to treatment is early and aggressive surgical debridement, along with high doses of intravenous antifungal therapy.
This patient, an uncontroled diabetic, started noticing cheek redness for 10 days, which rapidly expanded and progressed to edema and loss of vision in the next 7 days.
She was referred to the hospital and a diagnosis of mucormycosis was done upon arrival with a skin biopsy.
A left orbital exenteration, left full thickness face debridement was done, periosteum was send for trans-operatives pathology analysis, and was found no bone involvement.
To cover the defect after excision of the black necrotic tissue, a big free flap was needed.
The surgical team performed a ALT (Antero Lateral Thigh) free flap, that was 22 x 16 cm ALT flap, and anastomosed to the temporal artery.
Follow for more interesting cases!!