Thyroid Disorder Core Outcome Sets

04/12/2019

It is the most troublesome thing to do but still it is one of the most important thing we need to do in life.

EXERCISE!

Why Physical Exercise is Vital for a Healthy Brain and Body. Physical fitness through exercise is one of the most common pieces of advice offered by medics a...

28/11/2019

Kami mengalu-alukan sesiapa sahaja sama ada pesakit atau penjaga kepada pesakit untuk menyumbang kepada Penyelidikan kami 😊

Untuk maklumat lanjut, sila layari: https://tdcospatients.wordpress.com/

28/11/2019

Are you having thyroid problems? We would like to hear more from you! 😊

If you are interested, you may visit: https://tdcospatients.wordpress.com/

28/11/2019

You can do better. You can help in making healthcare a better service!

Oh wait, WE can make it better!

Choosing Wisely - a parody of the infectious Pharrell Williams song "Happy" - choose wisely when it comes to making health care decisions and if you choose w...

28/11/2019

What is actually "Core Outcome Sets?"

This video will give you some idea about it!

Sound improved version

28/11/2019

Hi everyone! You can learn more on what we are doing here by having a visit to our website!

Bahasa Malaysia “...estimate that 85% of all health research is being avoidably “wasted’ ” given that $200 billion per year is spent globally on health and medical research, it implied an annual waste of $170 billion”Glasziou P, Chalmers I. Paul Glasziou and Iain Chalmers: Is 85% of health...

28/11/2019

We want to be part of this revolution to better and safe medicine, reduce research waste and wise spending for the benefits of our patients.

To improve the design of clinical trials and clinical studies, we are developing an agreed standardized sets of research outcomes, known as ‘core outcome sets’, relevant to health service users and clinicians for adults patients with thyroid dysfunction. These outcome sets represent the minimum that should be measured and reported in all clinical trials of treatments for a specific condition, and can also be used in clinical audits. The core outcome sets will facilitate comparability of trials and use in systematic reviews increase the value of data, enable optimal data use and reduce waste in research.

Thyroid dysfunction encompassed the spectrum of disorders resulting from under- to over-secretion of thyroid hormones. This global health problem that substantially impacts on well-being and functional ability is modifiable with appropriate treatment.

Currently, there is no published core outcome set for use in interventions for thyroid dysfunction. Heterogenous outcomes measures vary in different clinical research studies limit the ability to combine and utilise data efficiently.

Participants in our research:
1. Healthcare professionals involved in the care of patients with thyroid disorders
2. Adults patients with thyroid dysfunctions and their carers or families
3. Researchers of thyroid dysfunction

“…Estimate that 85% of all health research is being avoidably “wasted’ ” given that $200 billion per year is spent globally on health and medical research, it implied an annual waste of $170 billion”(1)

“……..waste occurs during 5 stages of research production: question selection, study design, research conduct, publication, and reporting” (2) (3)

“much of these waste are avoidable or remediable and solutions are required. Progress has been made towards reducing the 85% of wasted effort in medical research—and the huge amounts of money misspent and harm caused to patients—but there’s still a long way to go” (4)

“patients undertake key roles in the research process brings responsibility for ensuring high quality research and value for money.” (5)

1. Glasziou p, chalmers i. Paul glasziou and iain chalmers: is 85% of health research really “wasted”?: bmj, 2016.
2. Macleod mr, michie s, roberts i, et al. Biomedical research: increasing value, reducingwaste. Lancet (london, england) 2014;383(9912): 101-4. Doi: 10.1016/s0140- 6736(13)62329-6 [published online first: 2014/01/15]
3. Glasziou p, altman dg, bossuyt p, et al. Reducing waste from incomplete or unusable reports of biomedical research. Lancet (london, england) 2014;383(9913):267-76. Doi: 10.1016/s0140-6736(13)62228-x [published online first: 2014/01/15]
4. Glasziou p, chalmers i. Research waste is still a scandal—an essay by paul glasziou and iain chalmers. 7>m/2018;363:k4645. Doi: 10.1136/bmj.k4645
5. Minogue v, cooke m, donskoy a-l, et al. Patient and public involvement in reducing health and care research waste. Research involvement and engagement 2018;4:5-5. Doi: 10.1186/s40900-018-0087-l