NIPT by Blessono

01/04/2024

Non-invasive Prenatal Testing (NIPT) is a type of blood screening done on expecting mothers to identify and check for genetic disorders and birth defects.

The test can be done as early as 10 weeks of pregnancy. However, to detect microdeletion/ microduplication which spans a smaller fragment of the DNA, it is recommended to test after 13 weeks of pregnancy to achieve the higher fetal fraction (%) required for better accuracy.

27/03/2024

NICC Test Malaysia

NICC Test (Non-Invasive ChromosomesCheck) is a blood screening conducted on pregnant women to detect chromosomal abnormalities. 84 microdelection and microduplication detection

19/03/2024

Case study : NIPT positive

A real case of Blessono patient, she is 33 year old lady with no underlying medical illness. This is her 5th pregnancy and she had previous pregnancy of Patau Syndrome. She came to our centre for NIPT test at 15weeks , a simple blood test procedure. The test result then shows high risk of Trisomy 21.

She was referred to a MFM (Maternal-Fetal Medicine) to proceed with confirmation test which require to take sample from amniotic fluid. Further test is consistent with NIPT , which still high risk for Trisomy 21 (Down's Syndrome) . Currently she is under MFM follow up for further management (detail scan, genetic counselling) .

This is our first NIPT that shows high risk result and the next confirmation test also consistent with our NIPT test.

So far we have succesfully served 60 customer for NIPT test . We are delighted to serve more customer from screening, management, treatment , mantainance and referral when necessary.

Thank you,
Dr Sharifah
Resident Medical Doctor

20/03/2023

Non-invasive Prenatal Testing (NIPT) is a type of blood screening done on expecting mothers to identify and check for genetic disorders and abnormalities. An NIPT test can be performed as early as 10 weeks of pregnancy, but the recommended time period is from 12 weeks of pregnancy.

https://blessono.com/nipt-test/

NIPT Test is a type of blood screening done on expecting mothers to identify and check for genetic disorders and abnormalities. NIPT test near me at Blessono Bangsar & Bukit Jalil.

29/09/2022

𝗡𝗜𝗣𝗧 𝗣𝗿𝗲𝗻𝗮𝘁𝗮𝗹 𝗧𝗲𝘀𝘁𝗶𝗻𝗴

💉 Non-invasive Prenatal Testing (NIPT) is a type of blood screening done on expecting mothers to identify and check for genetic disorders and abnormalities. An NIPT can be performed as early as 10 weeks of pregnancy, but the recommended time period is from 12 weeks of pregnancy.

𝗪𝗵𝘆 𝘆𝗼𝘂 𝘀𝗵𝗼𝘂𝗹𝗱 𝗴𝗲𝘁 𝗮𝗻 𝗡𝗜𝗣𝗧:

NIPT is a relatively expensive test but is an extremely great precaution to ensure preparedness for potential issues. Genetic abnormalities like chromosomal trisomy are extremely serious and cause many issues for the baby’s physical, mental and social well-being. For example, Down syndrome (Trisomy 21) causes reduced mental capacity and visible deformations, and Patau’s syndrome (Trisomy 13) has extremely high death rates, with more than 9 out of 10 children with Patau’s syndrome dying during the first year.

For the well-being of the family and the baby, being aware of potential dangers and consequences are necessary. So conducting preventive healthcare like detailed scans and NIPT gives time for families to prepare for the baby and possible conditions it may have, including learning about it, treatment or therapy plans, or researching about assistive technologies available to improve day-to-day life.

𝐇𝐨𝐰 𝐍𝐈𝐏𝐓 𝐰𝐨𝐫𝐤𝐬:

A mother’s blood contains traces of their baby’s DNA in it. So, the medical professional will extract blood from your arm with a needle and syringe and put it into a specific tube (cell-free DNA blood collection tube/BCT) to be sent off. The extraction process is just the typical blood withdrawal so you shouldn’t be worried.

The mother’s plasma contains the cell-free DNA (cfDNA) of the fetus, which is then sequenced to examine genetic information. In simpler terms, the DNA of the baby is then screened and analyzed from the mother’s blood sample.

𝐖𝐡𝐚𝐭 𝐝𝐨𝐞𝐬 𝐍𝐈𝐏𝐓 𝐭𝐞𝐬𝐭 𝐟𝐨𝐫:

✅Gender determination
✅Chromosomal trisomy (three chromosomes rather than the ✅normal pair of chromosomes):
Down syndrome (Trisomy 21)
✅Edwards syndrome (Trisomy 18)
Patau's syndrome (Trisomy 13)
✅Sex chromosome trisomies (###, XXY, XYY)
✅22 types of fetal chromosomal aneuploidy (abnormal number of chromosomes)
✅20 types of microdeletion/microduplication syndromes (parts of the gene are duplicated or deleted)


𝐖𝐡𝐲 𝐲𝐨𝐮 𝐬𝐡𝐨𝐮𝐥𝐝 𝐮𝐬𝐞 𝐁𝐥𝐞𝐬𝐬𝐨𝐧𝐨'𝐬 𝐍𝐈𝐏𝐓:

A modern and new sequencing technique that is highly sensitive and specific to screen for fetal aneuploidy (abnormal number of chromosomes) which can directly reflect the situation of abnormal chromosomes

The sequencing data is analyzed using an established bioinformatic pipeline with comprehensive databases (AKA, uses reliable and detailed information sources)

The result is calculated as Z-score, which represents the quantitative variations of the chromosome of interest
Z-score is helpful for the accurate judgment of NIPT results as it has: significantly associated with true-positive results
excellent clinical association

🤰𝗕𝗲𝗻𝗲𝗳𝗶𝘁𝘀 𝗼𝗳 𝗡𝘂𝗰𝗵𝗮𝗹 𝗧𝗿𝗮𝗻𝘀𝗹𝘂𝗰𝗲𝗻𝗰𝘆 (𝗡𝗧 𝗦𝗰𝗮𝗻)

✅To measure the number of fluids collected behind the fetal neck.
✅Early detection of many major prenatal defects
✅Used to identify pregnant women who are at a higher risk of developing preeclampsia.
✅Examine the fetal nose and palate
✅To measure the fetal heart rate
✅To detect multiple pregnancies with a solid diagnosis of chronicity

Blessono is Premium Ultrasound Centre. We are the first to incorporate AI-powered ultrasound services while offering extensive solutions for pregnant women.

1) Purchase from our Webstore - https://blessono.aoikumo.com/webstore #/Detail/62

(Walk in price RM1399, Webstore price 5% discount)
2) Call 010-545 0122 to schedule appointment

Result : 7 days