03/10/2025
🧬 Diet, Leaky Gut & Eczema: A Quick Overview
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“Did you know your gut and skin are connected? Emerging research suggests that when the gut lining becomes too permeable (“leaky gut”), unwanted molecules can leak into the bloodstream, trigger immune reactions, and worsen inflammation in skin conditions like eczema.
A diet high in sugar, processed foods, and low in fiber may worsen gut barrier function, while fiber-rich foods, prebiotics, and probiotics may support a healthier gut-skin balance.
While it’s not a silver bullet, paying attention to gut health through diet might help reduce flare frequency and severity. Always work with your doctor before trying major dietary changes.”
Sources:
- Severity of atopic dermatitis is associated with gut-derived metabolites and leaky gut-related biomarkers
Jinju Lee, Jeong Woo Park, et al.
Yonsei University College of Medicine, Seoul, Korea
Scientific Reports (2025)
- Food Sensitization Is Associated With Atopic Dermatitis Severity, Gut-Derived Metabolites and Leaky Gut in Adults
Anna Whalen, Maria C. Jenmalm, et al.
Linköping University, Sweden
Clinical and Translational Allergy (2025)
- Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation
Xiaoting Chen, Seung H. Yi, et al.
National Institute of Allergy and Infectious Diseases (NIAID), USA
Mucosal Immunology (2022)
-Epithelial barrier dysfunctions in atopic dermatitis: a skin-gut-lung model linking microbiome alteration and immune dysregulation
Carsten Flohr, Stephan Weidinger, et al.
King’s College London, UK & University of Kiel, Germany
British Journal of Dermatology (Review, 2018)
- Leaky gut and dermatological conditions: A systematic summary
Sarah B. Keating
University of San Francisco School of Nursing and Health Professions, USA
Journal of the Dermatology Nurses’ Association (2022)
