29/01/2026
ABOUT GENOTYPE 🤔😩👇
THEM: please help us we don’t know what to do they said we cannot marry😭😭
ME: but why?
THEM: Because our genotype is not compatible
ME: okay 👌 let me put you through something
DO YOU KNOW WHAT GENOTYPE MEANS?
Genotype can be simply defined as the genetic constitution of an individual organism.
This is different from your phenotype which is a description of your actual physical characteristics.
It is imperative to know your genotype before you say “yes” to that handsome guy or to that beautiful lady whom you wish to spend the rest of your life with or if you are in a relationship in which there are chances of conception.
The problem to avoid with genotype compatibility for intending couples is the SICKLE CELL DISEASE (A RECESSIVE DISORDER)--a very serious medical condition with high prevalence rates in Africa. (We will talk about it sometime)
ARE THERE TYPES OF GENOTYPE?
Types of Genotype
The genotypes in humans are AA, AS, AC, SS.
They refer to the hemoglobin gene constituents on the red blood cells. AC is rare whereas SS, AS and AC are abnormal.
NOW LETS TALK ABOUT THE COMPATIBILITY CHART 👇
Genotype Compatibility Chart
Study this carefully and comparing with the picture attached to the post👇👇👇
AA + AA = AA, AA, AA, AA (Excellent)
AA + AS = AA, AS, AA, AS, (Good)
AA + SS = AS, AS, AS, AS, (Fair)
AA + AC = AA, AA, AA, AC. (Good)
AS + AS = AA, AS, AS, SS, (Very Bad)
AS + SS = AS, SS, SS, SS, (Very Bad)
AS + AC = AA, AC, AS,SS. (Bad; Advice needed)
SS + SS = SS, SS, SS, SS, (Very Bad)
AC + SS = AS, AS, SS, SS, (Very Bad)
AC + AC = AA, AC, AC, SS. ( Bad; Advice needed)
THEM: what do you mean 😢???
ME:Compatible genotypes for marriage are:
✅✅If AA marries an AA. That’s the best compatible. That way you save your future children the worry about SCD and genotype compatibility, in fact even your pockets too😎
‼️If AA marries an AS. You’ll end up with kids with AA and AS which is good. But sometimes if you’re not lucky all the kids will be AS which limits their choice of partner, sha your pocket no go suffer
❌AS and AS should not marry, there is every chance of having a child with SS which means you and hospital will be friends and your pockets too will testify plus the pains you’re disposing your child into🤔
❌AS and SS shouldn’t think of marrying
❌And definitely, SS and SS MUST NOT MARRY 😡 since there’s absolutely no chance of escaping having a child with the sickle cell disease.
THEM: so what is your advice??😩🤔😭
ME: The only thing that can change the genotype is the bone marrow transplant (BMT). It has been proven to be the only promising permanent cure to SS, SC, and CC; HOWEVER, it is new, very expensive and cannot be done in any part of Africa. It also carries some risks. SO MY CONCLUSIVE ADVICE IS IF YOU CAN’T AFFORD AND YOU BOTH KNOW YOU ARE NOT COMPATIBLE, AVOID GOING INTO MARRIAGE OR CONCEPTION PROCESS!!!!!! Although God still perform miracles 😊
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