MulderLab

We develop complex and multifunctional nanomaterials, innovative synthesis methods as well as nanoparticle libraries.

The MulderLab spans two research teams, at Radboud University Medical Center and Eindhoven University of Technology, working on establishing nanotech-based immunotherapeutics. Nano-TMII is directed by Dr. Willem Mulder and is funded by the National Heart Lung and Blood Institute, the National Cancer Institute and NHLBI’s Program of Excellence in Nanotechnology. The mission of Nano-TMII is to develop and translate nanomedical approaches towards targeted therapy and molecular imaging of cardiovascular disease and cancer. The preclinical application in models of cardiovascular disease and cancer includes targeted therapy as well as the characterization of disease biology through nanoparticle-enhanced molecular imaging with computed tomography (CT), magnetic resonance imaging (MRI) and fluorescence imaging. Nano-TMII is also affiliated with the Department of Vascular Medicine at the Academic Medical Center (AMC) in Amsterdam. The clinical translation of anti-inflammatory nanotherapies is done in close collaboration with our AMC clinical partners. http://www.amc.nl/web/Research/Departments/Overview/Experimental-Vascular-Medicine/Experimental-Vascular-Medicine-1/Current-Research-4.htm

04/12/2020

Very nice blog on our recent cell paper:

Researchers have developed a nanoparticle that trains immune cells to attack cancer. By inducing this trained immunity, the nanoparticle slowed the growth of melanoma in mice, according to the NCI-funded study, and was more effective when combined with an immune checkpoint inhibitor.

25/11/2020

Our work is featured in the Arabic version of Scientific American Magazine:

باحثون يدربون الخلايا المناعية كي تهاجم الخلايا & #1575...

29/10/2020

This one definitely is a highlight, our paper in Cell!

This is the first time it is demonstrated that therapeutically inducing trained immunity is a very effective strategy for cancer treatment.

Check out the video we produced about the work:
https://youtu.be/-P0_8DFDs0U

Very proud of the tremendous amount of work by the Nano team🤙🏼

16/10/2020

We just received the proof of a highly anticipated paper that will be dropping in two weeks. It will be about cancer, trained immunity, nanotech and immunotherapy.

Feel free to checkout the new website of our startup, the continuation of that work:
https://ttxdiscovery.com

19/09/2020

Here's a snappy introduction to Trained Therapeutix Discovery. We are very excited! More news in the coming weeks and months ...

Prof. Dr. Mihai Netea from the Radboud University Medical Center and Prof. Dr. Willem Mulder from the Icahn School of Medicine at Mount Sinai introduce the b...

03/09/2020

At BioMedical Engineering and Imaging Institute's Nanomedicine Lab we value talent & creativity.

We are taking you back to the early 90s with Swiss student Eli Bre who performs a beautiful rendition of Alice in Chains' Down in a Hole.

Unplugged at the Scanner:

Eli Bre, a Swiss master's student in Professor Willem Mulder's Lab, flexes both her scientific muscles in designing and synthesizing siRNA nanoparticles, and...

16/07/2020

ImagingNation, Brought to you by the Biomedical Engineering and Imaging Institute at the Icahn School of Medicine, strives to provide insight to audiences of...

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http://www.mulderlab.com/

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