Terracotta TCM Europe BV

09/02/2026

Een oproep om meer klinisch onderzoek uit te voeren naar Medicinale Paddenstoelen!

In 2021 werd er een artikel gepubliceerd op het PubMed met als titel: “Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials.”

Van dit artikel volgt onderstaand de Abstract:
“Medicinal mushrooms have important health benefits and exhibit a broad spectrum of pharmacological activities, including antiallergic, antibacterial, antifungal, anti-inflammatory, antioxidative, antiviral, cytotoxic, immunomodulating, antidepressive, antihyperlipidemic, antidiabetic, digestive, hepatoprotective, neuroprotective, nephroprotective, osteoprotective, and hypotensive activities. The growing interest in mycotherapy requires a strong commitment from the scientific community to expand clinical trials and to propose supplements of safe origin and genetic purity. Bioactive compounds of selected medicinal mushrooms and their effects and mechanisms in in vitro and in vivo clinical studies are reported in this review. Besides, we analyzed the therapeutic use and pharmacological activities of mushrooms. (Bron: PMCID: PMC7826851 PMID: 33435246”

26/01/2026

22/01/2026

Over het algemeen is men in het Westen heel kritisch als het gaat om Chinese/Oosterse studies met betrekking tot medicinale paddenstoelen. Hoewel men daar al meer dan 5000 jaar kennis heeft vergaard over deze paddenstoelen.

Deze studie is het echt meer dan waard om gelezen te worden omdat het een kritische review is van studies over de laatste vijf jaar. Onderstaand een deel van de introductie van het gehele review met als titel gepubliceerd in mei 2025, (https://doi.org/10.3390/NU17111887)

Although the anti-cancer properties of edible and medicinal mushrooms have been
widely explored in the scientific literature, this review stands out by offering the most
current and comprehensive synthesis of the research published in the last five years to
provide theoretical support for exploring the potential of more mushroom bioactive com-
pounds in clinical practice. It focuses specifically on the anti-tumor potential of edible/me-
dicinal mushrooms, including Schizophyllum commune (Fries), Trametes versicolor (Lin-
naeus) Lloyd, Grifola frondosa (Dickson) Gray, Ganoderma lucidum (Fries) P. Karsten, Len
tinula edodes (Berkeley) Pegler, Laetiporus sulphureus (Bulliard) Murrill, Boletus edulis Bulliard, and Phellinus igniarius (Linnaeus) Quélet (Figure 1). The selection of these nine
mushrooms for this review was based on the fact that they have both been widely recog-
nized for their potential health benefits and extensively studied in the context of anti-tu-
mor activity. We report on a variety of insights into the mechanisms by which their bio-
active compounds exert anti-tumor effects on different types of cancer, providing strong
theoretical support for the further development of edible/medicinal mushroom anti-can-
cer products. This review also provides strong theoretical support for developing prod-
ucts that cater to consumers seeking natural solutions for overall healthcare or cancer pre-
vention.

(Bron: Critical Review on the Anti-Tumor Activity of Bioactive Compounds from Edible and Medicinal Mushrooms over the Last Five Years)

20/01/2026

Opnieuw een boeiend artikel over het gebruik van paddenstoelen. Absoluut een aanrader om dit artikel eens te lezen!

Het onderzoek werd uitgevoerd door onderzoekers verbonden aan het Centre for the Research and Technology for Agro-environmental and Biological Sciences, Portugal en draagt als titel: “Effect of Intracellular and Extracellular Mushroom Polysaccharides on Growth Inhibition of Human Carcinoma Cell Lines.”

Introduction: Mushroom polysaccharides play an important role in nutraceutical and functional food because they act as biological active modifiers. The aim of the present work involved the production, purification and partial characterization of intracellular (IPS) and extracellular polysaccharides (EPS) from several basidiomycete strains. Such polysaccharides were used to investigate their effect on growth of human carcinoma cell lines.
Methods: Mushroom polysaccharides were produced from several basidiomycete strains by submerged and solid state fermentations, assayed for superoxide radical scavenging activity, purified by gel filtration chromatography, analysed by FTIR and their effect on human carcinoma cell line was investigated by MTT method.
Results: Mushroom polysaccharides have revealed scavenging activity in the range of 22 – 81 % for Po (s) and Pe (2), respectively. FTIR analysis of polysaccharides showed absorption bands characteristics of these biological macromolecules. IPS inhibited cell growth of HeLa in the range of 16.8 – 27.01 % for Po (s) and Ga (1), respectively. EPS inhibited cell growth of HeLa, A459, A431 and OE21 in the ranges of 3.08 – 92.2 %, 13.8 – 97.4 %, 14.7 – 93. 8% and 25 – 94% for Il (1) and Ga (1), Gc (1) and Ga (1), Il (1) and Ga (1), Le (1) and Ga (1), respectively. Purified preparations of polysaccharides confirmed the growth inhibition of these biomolecules.
Conclusie: The present results strongly suggest growth inhibition of human carcinoma cell lines by mushroom polysaccharides and it will require a future research to understand its molecular mechanism of action.
Bron: Journal of Cancer Research Updates, 2019, 8, 29-41 29 ISSN: 1929-2260 / E-ISSN: 1929-2279/19 © 2019 Neoplasia Research.

15/01/2026

Een tinctuur gemaakt, door onze apotheker, van het vruchtlichaam van de Agaricus Blazei, ‘de paddenstoel van het leven!’

14/01/2026

Bevat de Maitake paddenstoel & Cordyceps!

12/01/2026

A preliminary mixed methods survey study of Reishi and Lion’s mane.

On the internet we found an interesting review on the use of Reishi and Lion’s mane.

Abstract: A significant proportion of epilepsy patients are resistant to conventional treatments. Functional mushrooms such as Reishi (Ganoderma lucidum) and Lion’s Mane (Hericium erinaceus) have recognized health benefits, including neuroprotective and anti-seizure effects. This mixed-methods study investigates the use of these mushrooms as adjunctive therapies for epilepsy among 19 participants, including caregivers on behalf of a minor. The majority (n = 14) met criteria for drug-resistant epilepsy (DRE). Participants completed surveys and structured interviews addressing functional mushroom use, quality of life (QoL), sleep quality, health outcomes, seizure activity, and caregiver burden. Qualitative data underwent thematic content analysis. Compared with the general population, participants utilizing functional mushrooms noted comparable scores in physical health, psychological health, social relationships, and environmental health. Self-report responses indicated improvements in seizure control, including reduced seizure frequency and severity, cognitive and developmental outcomes, and overall quality of life since starting use of functional mushrooms. Caregivers emphasized both benefits and ongoing challenges in managing epilepsy. Functional mushrooms are a sustainable and widely available resource, and the findings presented here suggest they could complement existing treatments for epilepsy, particularly in DRE, though further clinical trials are needed to establish efficacy, optimize dosing, and clarify mechanisms of action.


(Bron/Source: https://www.sciencedirect.com/science/article/pii/S2950199725002629)

10/01/2026

Een boeiend artikel om te lezen!

Er is veel te doen over de inzet van de Coriolus Versicolor. Er zou onvoldoende studie zijn gedaan naar de positieve effecten die deze paddenstoel als voedingssupplement heeft op het menselijk lichaam. Jammer genoeg mag deze paddenstoel, in Nederland beter bekend onder de naam Elfenbankje, niet worden verkocht hoewel de paddenstoel al eeuwenlang wordt gebruikt.

Als bedrijf kunnen en mogen wij niets zelf publiceren over deze paddenstoel, wel kunnen wij u verwijzen naar onderstaand wetenschappelijk artikel:

“In vitro treatment of triple-negative breast cancer cells with an extract from the Coriolus Versicolor mushroom changes macrophage properties related to tumorurigenes”. Een studie uitgevoerd in Polen welke ondersteund werd door the National Science Centre (NCN) in Poland (grant no. 2019/03/X/NZ6/00107) en gepubliceerd in december 2024.”

Bron: https://link.springer.com/article/10.1007/s12026-024-09574-6

30/12/2025

Vanuit Terracotta TCM Europe wensen wij u een mooie jaarwisseling en een voorspoedig en gezond 2026.
Ook in 2026 kunt u weer bij ons terecht voor onze voedingssupplementen en advies.

01/12/2025

Onderstaand de integraal overgenomen introductie op een review met als titel:” Medicinal Plants and Mushrooms with Immunomodulatory and Anticancer Properties -A Review on Hong Kong’s Experience.” Een zeer lezenswaardig stuk waarbij tevens wordt aangegeven hoe groot de acceptatie om ons heen is om natuurlijke producten als extra ondersteuning te gebruiken.

“Special plants have enjoyed the genuine trust of people around the world as being good for health, sometimes with special emphases on longevity. Ancient China, in particular, has lists of choice plants to maintain health. Since the Han Dynasty (206 B.C.–220 A.D.) remarkable documentations are available. One special area of intense interest and wisdom is related to infections and epidemics: from clinical presentations and treatment choices to public health measures. When bodily defense was mentioned in those days, although no assumption needs to be raised about immunological activities, it is also clear that advocates’ and narrators’ line of thought could be very near the modern concept of immunology at its most primitive level. Herbal formulations have been listed for the treatment of various infections in epidemics, their indications of use, and ways of preparation, which are handed down to today to facilitate therapeutic and preventive measures. The rich collection of plant items used for infection control have been studied in the laboratory and clinically along the modern directions of immunological activities—first with reference to infection as described in the old days and later diversifying into other immunological areas, notably cancer. This review will first briefly explore medicinal herbs in traditional Chinese medicine that have been studied in modern research platforms to identify their unique influences in some specific cellular and serological tests related to immunological activities. Some of these herbs have been selected in our home-ground to serve our aspirations on cancer treatment and epidemics. Bron: Molecules 2021, 26, 2173. https:// doi.org/10.3390/molecules26082173.”

23/11/2025

Opnieuw een recent artikel met een mooi perspectief voor verder onderzoek en gebruik van paddenstoelen. Het artikel werd in mei 2025 gepubliceerd en heeft als titel: “Critical Review on the Anti-Tumor Activity of Bioactive Compounds from Edible and Medicinal Mushrooms over the Last Five Years.”


Zeer waardevol om te lezen vooral ook omdat er een groot aantal internationale studies werdenverzameld die daarna zorgvuldig voor verder onderzoek werden geselecteerd. Lees alstublieft niet alleen onderstaande abstract - die integraal werd overgenomen -, maar vooral ook punt 4.2. Perspective.

Abstract:
“In recent years, the incidence rate of cancer has been on the rise all over the
world, and the age of cancer patients has shown a younger trend, which seriously endangers patients’ health. Edible/medicinal mushrooms have not only become a new source of nutritional supplements but have also emerged as a promising adjunct to conventional medicine, either by directly or indirectly killing tumor cells and enhancing immunity, or through their use in conjunction with modern cancer therapies to enhance their efficacy or reduce their side-effects, improving patients’ quality of life. Although the anti-cancer potential of edible and medicinal mushrooms has been widely studied in the past, this review focuses on the most recent literature from the last five years, providing an up-to-date and comprehensive summary of the current findings. In this review, we aim to analyze the anti-cancer effects of edible/medicinal mushrooms, including Schizophyllum commune, Trametes versicolor, Grifola frondosa, Ganoderma lucidum, Lentinula edodes, Laetiporus sulphureus, Boletus edulis, and Phellinus igniarius, as well as their potential anti-cancer mechanisms, providing strong theoretical support for the further development of edible/medicinal mushroom anti-cancer products. (Bron: Nutrients 2025, 17, 1887 https://doi.org/10.3390/nu17111887).”

22/11/2025

Morgen een nieuw item over de kracht van paddenstoelen, een artikel over een kritisch review over de laatste vijf jaar (publicatie 2025) Alles wijst op het verder onderzoeken en toepassen van deze natuurproducten met en naast de reguliere geneeskunde.
Vergeet ook de Black Friday aanbieding niet!!