DermNet

The authoritative resource about dermatology and the skin: dermnetnz.org The world's most popular skin website - written and edited by Dermatologists worldwide.

29/10/2025

Have you encountered patients with this condition? Read the case here: https://dermnetnz.org/cases/swollen-painful-palms-following-water-exposure

22/10/2025

Mastocytoma is the name given to a form of cutaneous mastocytosis in which there is a dermal accumulation of mast cells forming one to thee solitary lesions.

Pictured is positive Darier sign where the mastocytoma becomes active and inflamed following rubbing.

Read here: https://dermnetnz.org/topics/mastocytoma

19/10/2025

What is the most common virus associated with hand, foot, and mouth disease? Learn more about the condition on our DermNet page here: https://dermnetnz.org/topics/hand-foot-and-mouth-disease

15/10/2025

Gottron papules are purple papules and plaques over the tops of the small joints of the hands found in dermatomyositis. Read more about other clinical signs and information about the condition here: https://dermnetnz.org/topics/adult-onset-dermatomyositis

12/10/2025

Transient acantholytic dermatosis most often affects Caucasian men over 50 years of age with sundamaged skin (mean age at diagnosis 61 years). It is less common in skin of colour, women, and younger adults.

Risk factors include sun-exposure, sweating, fever, malignancy, and being hospitalised or bedridden. A Grover-like rash has been reported during the febrile phase of COVID-19.

Transient acantholytic dermatosis is increasingly reported with the use of BRAF-inhibitors such as vemurafenib and dabrafenib monotherapy, and cytotoxic chemotherapy drugs.

08/10/2025

The prognosis for oral lichen planus is uncertain. It can clear up within a few months or persist (with or without treatment) for decades. There are often periods of remission and relapse. Read more about the condition on this carousel and dermnet page here: https://dermnetnz.org/topics/oral-lichen-planus

05/10/2025

Lichen simplex results from a chronic ‘itch-scratch cycle’; following repetitive excoriation and scratching, well circumscribed thickened patches develop.

The inciting stimulus for the itch can be due to a variety of reasons:
- Primary lichen simplex develops on normal skin
- Secondary lichen simplex can follow an underlying itchy dermatosis — atopic dermatitis, psoriasis, scabies, xerosis
- Neural-mediated stimulus that triggers itch — brachioradial pruritus, radiculopathy
- Systemic disease associated with pruritus — uraemia, polycythaemia vera, malignancy
- Environmental triggers — heat, sweat, chemical irritants, insect bite.

Read more here: https://dermnetnz.org/topics/lichen-simplex

01/10/2025

Iontophoresis is a procedure in which an electrical current is passed through skin soaked in tap water (not distilled water), normal saline (0.9%), or a solution containing an anticholinergic medication, which allows ionised (charged) particles to cross the normal skin barrier. It reduces sweating and enhances the delivery of drugs and macromolecules into and through the skin. It is safe, effective and inexpensive.

Iontophoresis should not be used by: patients who are epileptic, have heart conditions or pacemakers, a metal implant or pregnant.

Read about iontophoresis here: https://dermnetnz.org/topics/iontophoresis

28/09/2025

What are your differentials for a patient presenting with this? Read the entire clinical case here: https://dermnetnz.org/cases/58-year-old-with-red-tight-skin-on-upper-back

24/09/2025

Topical fluorouracil 5% cream is often abbreviated to 5-FU. The trade name in New Zealand is Efudix™ and it is a prescription medicine. It is a cytotoxic agent or antimetabolite and it is toxic to living cells, especially to certain cancer or precancerous cells.

Fluorouracil is a pyrimidine analogue that irreversibly binds within a cell to thymidylate synthetase. This prevents the incorporation uracil into nuclear RNA, which destroys abnormal cancer cells.

Read more on our dedicated DermNet page: https://dermnetnz.org/topics/5-fluorouracil-cream

21/09/2025

Discoid lupus erythematosus (DLE) is a chronic scarring skin condition. It is the most common form of cutaneous lupus. DLE is typically located on the nose, cheeks, ear lobes, and conchal bowl (Shuster sign, as pictured).

For more information, see https://dermnetnz.org/topics/discoid-lupus-erythematosus

17/09/2025

Read more about Stewart-Treves Syndrome here: https://dermnetnz.org/topics/stewarttreves-syndrome

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DermNet NZ has become a world renowned resource all about the skin. The website is owned by the DermNet New Zealand Trust. It has been HON (Health-on-The-Net) certified since 1996 and is in continuous development to provide information about the skin over any desktop or mobile web browser.

Our mission is to make authoritative information about the skin accessible to anyone in the world with an internet connection.

Dr Amanda Oakley, DermNet's founder, was most recently honoured by being appointed by Her Majesty The Queen as a Companion of the New Zealand Order of Merit in recognition of her services and contribution to Dermatology. She was also awarded the Google Technology Service in the Charitable Sector's Lifetime Service Award at the New Zealand Charities Technology Awards in March 2017 and was a finalist in two categories the New Zealand Woman of Influence awards in June, 2017.