Alvarez Dental Clinics

Alvarez Dental Clinics General Dentistry, Esthetic Dentistry, Orthodontics, Airway Orthodontics, TMD Specialist

03/10/2025
25/09/2025
12/09/2025

Scientists are starting to suspect that Alzheimer’s disease may not only be an issue of aging brains — it could actually have its roots in the mouth. Growing evidence suggests that chronic gum disease might set off a chain reaction leading to Alzheimer’s.

In a landmark 2019 study, researchers at the University of Louisville identified Porphyromonas gingivalis — the main bacteria behind persistent gum infections — inside the brains of people who had died with Alzheimer’s. Even more striking, the same bacterial toxins were detected in the brains of individuals with no dementia symptoms, hinting that damage could begin many years before memory loss appears.

Animal studies reinforced these concerns: when mice were exposed to this gum bacterium, it didn’t stay confined to the mouth. Instead, it migrated to the brain, elevated amyloid-beta proteins tied to Alzheimer’s, and triggered inflammation. In the same research, a new drug, COR388, was tested — it successfully reduced the bacterial load in the brain and lowered amyloid buildup in mice, raising hopes that such therapies might one day slow or even prevent the disease.

While scientists caution that it’s still too early to confirm gum disease as a direct cause of Alzheimer’s, these discoveries are significant. They turn the old assumption upside down — rather than dementia leading to poor oral hygiene, it may be oral bacteria quietly infiltrating the brain and sparking damage long before memory decline begins.

📄 Research Reference
PMID: 30746447
PMCID: PMC6357742

04/09/2025

🚫 Periapical Lesions: The Silent Damage Hidden in Untreated Dental Abscesses

This skull offers a striking example of the destructive power of untreated dental infections. Around the first molars of both the upper (maxillary) and lower (mandibular) arches, we can clearly see periapical lesions—dark, hollow areas caused by long-standing abscesses.

Periapical lesions form when bacteria from deep dental caries or pulp necrosis spread beyond the root canal into the surrounding bone. Without treatment, the infection causes chronic inflammation, bone resorption, and destruction of surrounding tissues. Over time, this can compromise the stability of the teeth, leading to pain, swelling, tooth loss, and even systemic complications such as cardiovascular disease, diabetes aggravation, or in rare cases, life-threatening sepsis.

What makes this case so impactful is how visibly the lesions have altered the bone structure—an unmistakable reminder of why endodontic treatment or extraction is essential once an abscess is diagnosed.

👉 This image is not just a look into the past, but a lesson for modern dentistry: prevention, early diagnosis, and timely treatment are critical in protecting oral and overall health.

24/08/2025
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31/07/2023

Look at that improvement! 😍✨

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Book your appointment now!

29/03/2022

Address

Quezon City

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm
Saturday 9am - 5pm
Sunday 9am - 5pm

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+639985515081

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