11/11/2025
We work on children, but also on the other end of the age spectrum. Manjeet Singh is researching Alzheimer's Disease in Pakistan and links to cousin marriages (63% of all marriages, a global high). So far, there have been no studies or data from Pakistan on Alzheimer's Disease so Singh wants to study the genes linked to it. His pilot study of 200 volunteers at our field sites and at AKU in Karachi began in May. The elderly volunteers are tested, get MRIs and give blood (for genomic sequencing). Their average age is 68 years. If anyone in your family suffers from Alzheimer's they can become part of his larger study that is in the works. The more we learn about what causes it, the better we can protect ourselves. In India they are discovering, for example, environmental pollution is linked to AD.
Dr Imran Nisar started a weekly research seminar in which one member of the Department of Paediatrics & Child Health, the Infectious Disease Research Lab or the Centre for Bioinformatics and Computational Biology (all run by Paediatrics faculty) share what they are working on. All the researchers attend so they stay in the loop about the work at AKU.