USMLE Qbank

19/12/2025

20/11/2025

A 10-year-old boy with a history of hemophilia A presents with a knee swelling. He has received multiple prior Factor VIII infusions. Lab studies show prolonged aPTT that does not correct on mixing study. Which of the following is the most appropriate next step in management?

A) Repeat high-dose Factor VIII infusion
B) Desmopressin (DDAVP)
C) Recombinant activated Factor VII (rFVIIa)
D) Cryoprecipitate

20/09/2025

It would be a really Bad News for all the IMGs USMLE Test takers.

29/08/2025

A 64-year old man comes to the clinic with cramping pain in his right thigh after walking 2 blocks. The pain goes away once he stops and rests for few minutes. The patient has no history of diabetes, coronary artery disease or stroke although he has a 35-pack years smoking history. Vitals are normal. On examination, the Femoral pulses are normal but the popliteal and dorsalis pedis pulses are diminished in the right leg. He is prescribed low-dose Aspirin and high intensity statin.
Which of the following is the next best step in the management of this patient ?

𝑨. Arteriography followed by a surgical bypass procedure
𝑩. CT Angiography followed by stenting
𝑪. Pentoxifylline
𝑫. Supervised exercise programs
𝑬. Warfarin

27/08/2025

Identify the findings on this Chest Xray of a 1 year old child !

27/08/2025

SA node vs Ventricular vs Skeletal muscle action potential curves.

27/08/2025

A 67-year-old man with a history of chronic obstructive pulmonary disease (COPD) presents with fever, productive cough with yellow sputum, and shortness of breath for 3 days. On examination, his temperature is 38.5°C (101.3°F), blood pressure 120/78 mmHg, pulse 102/min, respiratory rate 24/min, and oxygen saturation 90% on room air. Lung auscultation reveals crackles and bronchial breath sounds over the right lower lung field. A chest X-ray shows consolidation in the right lower lobe.

Which of the following is the most likely causative organism?

A. Mycoplasma pneumoniae
B. Streptococcus pneumoniae
C. Klebsiella pneumoniae
D. Legionella pneumophila
E. Pseudomonas aeruginosa

18/03/2025

A 45-year-old man with HIV is started on an antiretroviral regimen containing tenofovir, emtricitabine, and dolutegravir. Three months later, he presents with new-onset lower back pain and difficulty walking. Lab results show:
• Serum creatinine: 2.1 mg/dL (↑)
• Urinalysis: Proteinuria, normoglycemic glycosuria, phosphaturia
• Serum phosphate: Low
• Bone density scan: Osteomalacia

Which of the following is the most likely cause of this patient’s symptoms?

A. Dolutegravir-induced myopathy
B. Emtricitabine-induced hypersensitivity
C. Tenofovir-induced renal toxicity
D. Immune reconstitution inflammatory syndrome (IRIS)
E. Opportunistic infection-related osteomyelitis

18/03/2025

A 52-year-old right-handed man with a history of medically refractory epilepsy undergoes a specific brain surgery to reduce the frequency of his seizures. After the procedure, neurological examination reveals that when an object is placed in his left hand with his eyes closed, he is unable to name it. However, he can correctly identify and use the object when allowed to manipulate it with his right hand. His ability to name objects placed in his right hand remains intact.

Which of the following best explains this patient’s deficit?

A) Damage to the primary somatosensory cortex
B) Disruption of interhemispheric communication
C) Dysfunction of the left occipital lobe
D) Impaired contralateral motor control
E) Lesion in Wernicke’s area

12/03/2025

A 49-year-old woman comes to the office for evaluation of abnormal uterine bleeding. The patient has irregular me**es for the past 2 years but now she has been bleeding daily for 2 weeks. She also has increased abdominal bloating and pressure. Medical history includes early-stage breast cancer diagnosed at age 45 and managed with tamoxifen for the past 4 years. On examination, there is a midline, immobile pelvic mass at the level of umbilicus. The patient undergo Hysterectomy with Bilateral salphingo-oopherectomy. The final pathology report notes nuclear atypia and numerous mitosis in the affected portion of myometrium. Which of the following is the most likely diagnosis ?
A. Adenomyosis
B. Cervical carcinoma
C. Endometritis
D. Uterine Fibroids
E. Uterine Sarcoma

08/03/2025

Watershed territories of the Brain,
On sequence Fluid Attenuated Inversion Recovery (FLAIR; at the top) and corresponding illustrative cases Diffusion-Weighted Imaging (DWI; below); in blue: cortical watershed, in red.