Instituto de Biofísica e Engenharia Biomédica

Instituto de Biofísica e Engenharia Biomédica O Instituto de Biofísica e Engenharia Biomédica da Faculdade de Ciências da Universidade de Lisboa é financiado pela FCT.

The Institute of Biophyisics and Biomedical Engineering in the Faculty of Sciences, University of Lisbon is funded by FCT. Ensino
No âmbito do ensino, o IBEB tem vindo a assegurar, desde 1992, o Mestrado (e Programa Doutoral desde 1996) em biofísica e engenharia biomédica, e a orientar estudantes de doutoramento em áreas ligadas à biofísica. Desta actividade resultaram 56 teses de mestrado e 29 teses de doutoramento. O IBEB formou grande parte dos recursos humanos em Portugal nestas áreas, que têm sido contratados por numerosas instituições nacionais e estrangeiras. O IBEB está actualmente envolvido no ensino de Engenharia Biomédica e Biofísica a todos os niveis de formação universitária:
Na Licenciatura e no Mestrado em Engenharia Biomédica e Biofísica, da responsabilidade do Departamento de Física da FCUL. No Doutoramento (3º ciclo segundo o acordo de Bolonha) em Engenharia Biomédica e Biofísica. Investigação
A investigação no IBEB explora a interface da Engenharia Biomédica com a Biofísica e com a Medicina, com especial destaque para as seguintes áreas:
-imagem molecular e reconstrução de imagem
-aquisição e processamento de sinais electrofisiológicos (electroencefalografia, magnetoencefalografia, electrocardiografia)
-imagens por ressonância magnética nuclear
-estimulação magnética transcraniana
-processamento de imagens médicas
-dinâmica da actividade cerebral e cardíaca
-interface homem-computador

Somos financiados pela Fundação para a Ciência e Tecnologia UIDB/00645/2020 e UIDP/00645/2020.

✨ From October 8th to 11th, students from IBEB/FCUL participated in the 41st Scientific Meeting of the European Society ...
30/10/2025

✨ From October 8th to 11th, students from IBEB/FCUL participated in the 41st Scientific Meeting of the European Society of Magnetic Resonance in Medicine and Biology (ESMRMB 2025) in Marseille, France.

The following research projects were presented:

🗣️ "MRI-Based 3D Modelling of the SOD1 Mouse": Presented by PhD student Leonor de Oliveira Pires (Supervisor: Professor Sofia Fernandes).

🗣️ "Tackling the challenge of improving the automated diagnosis of Autism spectrum disorders: assessing the potential of non-standard brain connectivity metrics, deconvolution approaches and machine learning classifiers for the analysis of intrinsic fMRI data": Presented by PhD student Lucianna Lopes do Couto (Supervisor: Professor Alexandre Andrade).

🗣️ "Partial Volume Effects across Tumor Regions in ASL Perfusion Imaging of Glioblastoma": Presented by Master's student Afonso Simões (developed under the "Bolsas Gulbenkian Novos Talentos" program, with LaSEEB).

👏 A new paper has been published as a result of the Master's dissertation work by student Tiago Silva, supervised by IBE...
22/10/2025

👏 A new paper has been published as a result of the Master's dissertation work by student Tiago Silva, supervised by IBEB's researchers Daniela Godinho and Raquel Conceição.

✨ The paper, titled "Machine and deep learning applied to medical microwave imaging: a scoping review from reconstruction to classification", was published in Progress in Biomedical Engineering by IOP Science. It presents a state-of-the-art review of the use of machine and deep learning for medical microwave imaging. By analysing the latest studies and methodologies, the review addresses the current state of machine learning-enhanced medical microwave imaging and sheds light on its potential for clinical applications.

🔗 Read more at https://iopscience.iop.org/article/10.1088/2516-1091/ae0bd3

✨ IBEB’s PhD student Leonor de Oliveira Pires attended the 8th IEEE Portuguese Meeting on Bioengineering (ENBENG 2025) o...
20/10/2025

✨ IBEB’s PhD student Leonor de Oliveira Pires attended the 8th IEEE Portuguese Meeting on Bioengineering (ENBENG 2025) on 25-26 September 2025 in Aveiro, Portugal.

Leonor de Oliveira Pires presented her poster and contributed paper “Screening the Effects of Tissue Electric Conductivity and Anatomical Variability on Computer Models of tsDCS in SOD1 Mice“, co-authored by IBEB's professor and full member Sofia R. Fernandes.

✨ PhD student Ana Catarina Pelicano and IBEB's researcher Raquel Conceição were interviewed for "Podcast da Radiociência...
17/10/2025

✨ PhD student Ana Catarina Pelicano and IBEB's researcher Raquel Conceição were interviewed for "Podcast da Radiociência" at 18º Congresso do Comitê Português da URSI. Ana Catarina Pelicano talked about her work which earned her the 2nd place in the Best Student Paper Award and professor Raquel Conceição, as Vice-President of Comission K of URSI Portuguese Commitee, talked about student participation in the congress.

🎤 Listen on Spotify: https://open.spotify.com/episode/4LPntX7yrcPFaUJc2IzELz?si=4d7ee1f9cf324114&nd=1&dlsi=d40d2d67a2e4417b

✨ On October 3rd, IBEB welcomed the first-year students of the Bachelor’s Degree in Biomedical Engineering and Biophysic...
16/10/2025

✨ On October 3rd, IBEB welcomed the first-year students of the Bachelor’s Degree in Biomedical Engineering and Biophysics.

👥 The visit began with an introduction to IBEB’s three main research lines, presented by coordinators and integrated members Alexandre Andrade, João Coelho, and Hugo Ferreira. Students then had the opportunity to explore the institute’s laboratories and research spaces, gaining a closer look at the technologies and methods used in ongoing projects. The event concluded with engaging presentations by professors and integrated members Nuno Matela, Raquel Conceição, Sofia Fernandes, and Tânia Gonçalves, who shared insights into their research and the exciting work being developed at IBEB.

✨ It was a pleasure to welcome the new students and share with them the research being carried out at IBEB!

✨ On the 26th of September, IBEB attended the European Researchers' Night at Jardim do Príncipe Real presenting two rese...
15/10/2025

✨ On the 26th of September, IBEB attended the European Researchers' Night at Jardim do Príncipe Real presenting two research projects of our institute and in the context of Biomedical Engineering and Biophysics course of the Department of Physics of Faculty of Sciences of University of Lisbon:

🧠 Studying the Brain with Technology: 3D Models and Non-Invasive Electrical Stimulation (presented by researcher Sofia Fernandes and prepared by PhD student Leonor Pires)

👩‍⚕️ Microwave Medical Imaging for Breast Cancer Detection (presented by researchers Daniela Godinho and Raquel Conceição, and PhD student Henrique Lopes, accompanied by PhD student Shaheer Mirza)

🎤 RTP interviewed researcher Sofia Fernandes, an interview that can be watched at https://www.rtp.pt/play/p14264/e878116/portugal-em-direto/1365947 starting at minute 9:11.

✨ The paper “Towards a Less Invasive Treatment for Head and Neck Cancer: Initial Evaluation of Gold Nanoparticle-Mediate...
06/10/2025

✨ The paper “Towards a Less Invasive Treatment for Head and Neck Cancer: Initial Evaluation of Gold Nanoparticle-Mediated Photothermal Therapy” was recently published in the journal Pharmaceutics.

👏 This work, developed by PhD student Mariana Amaral, was carried out under the supervision of IBEB’s full members João Coelho and Hugo Ferreira, in collaboration with Catarina Reis and Manuela Gaspar from Faculdade de Farmácia da Universidade de Lisboa (FFUL).

✨ This study aimed to synthesize and characterize gold nanoparticles (AuNPs), evaluate their safety without laser activation, and assess their efficacy with laser activation. Their physicochemical and photostability over three months and sterility were confirmed. In vitro safety was tested using human non-cancerous and head and neck cancer (HNC) cell lines, while in vivo biocompatibility was evaluated in the hen’s egg chorioallantoic membrane (CAM) model, with no adverse effects observed. Upon laser activation, AuNPs reduced HNC cell viability by 50–70%, including head and neck squamous cell carcinoma (HNSCC) lines. In vivo biodistribution studies showed that AuNPs remained at the injection site for up to one month without toxicity. Overall, the developed AuNP formulation demonstrates stability, biocompatibility, and prolonged local retention, key attributes for effective and targeted PTT. These findings support the potential of AuNP-mediated photothermal therapy as a promising treatment modality for HNC, although further preclinical and clinical studies are needed to optimize treatment parameters.

🔗 Read more at https://doi.org/10.3390/pharmaceutics17101283

✨ On September 25th, the Physics Day took place — a day of lectures promoted by the Department of Physics that brought t...
03/10/2025

✨ On September 25th, the Physics Day took place — a day of lectures promoted by the Department of Physics that brought together PhD students from various fields (Physics, Physics and Astrophysics, and Biomedical Engineering and Biophysics) and companies.

👥 IBEB was represented by several PhD students in Biomedical Engineering and Biophysics who presented their work: Ana Catarina Pelicano, Ana Sofia Verde, Beatriz Antunes, Caio Junior, Duarte Saraiva, Emanuele Bianchi, Henrique Lopes, João Mendes, Muhammad Shaheer Mirza, and Rafael Esteves.

✨ The paper “A computational model of tsDCS effects in SOD1 mice: from MRI-based design to validation” was recently publ...
02/10/2025

✨ The paper “A computational model of tsDCS effects in SOD1 mice: from MRI-based design to validation” was recently published in the journal Computers in Biology and Medicine by PhD student Leonor de Oliveira Pires and IBEB researcher and professor Sofia Rita Fernandes.

👥 The work was developed under the scope of the European consortium DC4MND ("Multidimensional mechanistic investigations of trans spinal direct current stimulation in motor neuron disease"), in collaboration with Bartosz Wasicki and Marcin Bączyk (University of Poznań, Poland), Alireza Abaei, Jelena Scekic-Zahirovic, and Francesco Roselli (University of Ulm, Germany).

✨ The study presents a 3D computational model of a SOD1 mouse (an in vivo model of Amyotrophic Lateral Sclerosis) designed to predict the effects of trans-spinal direct current stimulation (tsDCS).

🔗 Read more at https://www.sciencedirect.com/science/article/pii/S0010482525014349

Endereço

Instituto De Biofísica E Engenharia Biomédica, Faculdade De Ciências Da Universidade De Lisboa. Campo Grande
Lisbon
1749-016

Telefone

+351 217 500 177

Website

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