The Endocrine Club

20/02/2026

Persistent hormonal imbalance across trimesters conveys elevated risk ofAutism
JCEM Nov 2025

19/02/2026

53 F with recent history of head trauma, The visit after hospital discharge her main concern was she wakes up 4-6 times to urinate.
agreed to do one test only
Urine osmolality came low 145 ( 150-1050)
What is the best SINGLE step ?

19/02/2026

AHA/ACC Guidelines on Aspirin

19/02/2026

Semaglutide increased walking distance in patients with symptomatic peripheral artery disease and type 2 diabetes

Lancet. 2025;405(10489):1580

19/02/2026

Diabetes Management In
Glibenclamide should not be used because of very high risk of hypoglycemia
Others
1- Change to DPP4-I before ramadan
2- Or decrease the dose if once daily at iftar
3- If twice daily give full dose at Iftar and half dose at suhoor

19/02/2026

TSH is the first step to rule out hyperthyroidism so you don’t biopsy an active nodule

19/02/2026

37 M came with Ultrasound report with 1.2 x1 cm left thyroid nodule . what is the most important next step?

18/02/2026

Dairy products have the highest calcium content per serving.

Uptodate

18/02/2026

Diabetes Remission

Current research supports the idea that remission of type 2 diabetes is increasingly achievable.

A 2023 study published in Diabetes Care showed that an intensive low-energy total diet replacement program in Australian primary care led to diabetes remission at 1 year in about half of the participants with recently diagnosed type 2 diabetes, with higher remission rates tracking with greater weight loss. Meanwhile, a September 2025 systematic review and meta-analysis in the same journal pooled 18 nonsurgical randomized controlled trials and found that structured interventions, particularly those producing substantial weight loss, consistently achieved clinically meaningful remission rates. https://mdsc.pe/3ONf464

18/02/2026

In a young (aged

18/02/2026

Artifactual hypoglycemia always should be considered in samples from patients with leukocytosis, severe hemolysis, or erythrocytosis; in such samples, the abundant cells consume glucose after blood collection, leading to a misleadingly low glucose concentration

U2D

18/02/2026

After a median follow-up of four years, the primary outcome (a composite of death from cardiovascular causes, myocardial infarction, or stroke) was not significantly different between Dulaglatide and Tirzepatide

U2D