The Endocrine Club

The Endocrine Club General endocrinology and diabetes practical points
Chairman/admin :
Abdulqawi Almansari MBBS FACP FACE

Chairman Abdulqawi Almansari MD FACP FACE
Consultant endocrinologist
Myclinic alsafa Jeddah
American board of Endocrinology Diabetes and Metabolism2000
American Board internal Medicine 1998

29/04/2026

Acromegaly Diagnosis
IGF-1>1.3X ULN and clinical signs
OGTT might be additionally useful

Consensus on criteria for acromegaly diagnosis and remission. Pituitary. 2024

29/04/2026

Risk of stroke or CAD in diabetic patients is higher with these factors
Longer duration than 10 years
Uncontrolled DM
microalbuminurea and low GFR
Microvascular complications

29/04/2026

Tight Glycemic Target in Gestational Diabetes Reduces Risks

Diabetes Research and Clinical Practice. April 2026 issue

28/04/2026

A sharp rise in type 2 diabetes among younger populations is signaling a public health emergency, with diagnoses occurring increasingly in patients under 40. This shift often results in a more aggressive disease course and a longer lifetime exposure to complications, including cardiovascular disease and renal failure

Medscape

28/04/2026

A full replacement dosage in an individual who is completely reliant on thyroid hormone is estimated to be 1.6 mcg/kg per day.
ESAP 2025

28/04/2026

35%of people with T2DM have CVD
Based on CAPTURE study

28/04/2026

SGLT2i (Canagliflozin) increased serum phosphorus, which caused normocalcemic Hyperparathyroidism

JCI Insight 2018 Apr 19

28/04/2026

In a 13-year follow-up study on 3,000 young, those who consumed much
more fast-food were found to weigh an average of ~6kg more and have larger waist circumferences than those with the lowest fast food intake.
Front. Endocrinol. Sept 2021

28/04/2026

Work up of hyperaldostronism
Blood samples collected in the morning Aldosterone ,Renin , Potassium
from a seated, ambulatory patient . Most antihypertensive medications( Except potassium sparing diuretics) can be continued during biochemical testing, and posture stimulation is not required
U2D

27/04/2026

Before you add another pill or increase the strength, ask your patient:
"Are you taking your medication regularly?"

27/04/2026

We would advise taking prednisolone immediately on waking, before breakfast to produce a detectable concentrations of prednisolone as early as possible. Currently the package inserts suggest that prednisolone should be taken after breakfast. Whilst this might be appropriate for patient on anti-inflammatory doses, this may not be appropriate for individuals taking replacement therapy.

Endocrine Abstracts (2016) 44 P23

27/04/2026

Albuminurea indicates endothelial damage,and early sign of CKD and CVD
Annual spot urine for albumin is indicated once DM2 is diagnosed ( after 5 years in DM1)

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